NCT00512382

The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Wheezing\Coughing Babies

The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Asthmatic/Wheezing Babies Using Impedance and Wheezy Monitoring

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 15 (actual)
• Sponsor: Wolfson Medical Center · Other Government
• Sex: All
• Age: 1 Month – 18 Months
• Healthy volunteers: Accepted

Summary

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor and vice versa.

Detailed description

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor.However, If cough/wheeze precedes GER recordings it points to cough/wheeze being the possible precipitating factor. The recordings will be investigated 1 minute before and one minute after each event.

Conditions

• Asthma
• Cough
• Wheezing

Interventions

Type	Name	Description
DEVICE	WEEM - Wheezy Monitoring	loudspeaker recording (WEEM) is attached externally to the chest simultaneously with PH-Impedance.

Timeline

• Start date: 2007-03-01
• Primary completion: 2011-03-01
• Completion: 2011-09-01
• First posted: 2007-08-07
• Last updated: 2011-09-07

Locations

1 site across 1 country: Israel