| Not Yet Recruiting | Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG NCT07348991 | I.M. Sechenov First Moscow State Medical University | — |
| Not Yet Recruiting | Longitudinal Validation of CIRC Technologies NCT07081711 | The Cleveland Clinic | — |
| Recruiting | Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest NCT07174986 | Gabriel Riva | Phase 2 / Phase 3 |
| Not Yet Recruiting | Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active People NCT07014579 | University of Leicester | — |
| Recruiting | Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest NCT06672159 | St. Olavs Hospital | N/A |
| Recruiting | Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT- NCT06745778 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Active Not Recruiting | Assessment of a Chronically Implanted Parasternally Delivered EV-ICD Lead (ASCEND EV) Study NCT06592001 | AtaCor Medical, Inc. | N/A |
| Not Yet Recruiting | The OSIRIS ECPR Trial NCT06805344 | General University Hospital, Prague | N/A |
| Recruiting | Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest NCT06071910 | Queen Mary University of London | N/A |
| Recruiting | Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm NCT06281977 | Ottawa Heart Institute Research Corporation | Phase 3 |
| Enrolling By Invitation | Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT) NCT06964152 | University of California, San Diego | N/A |
| Not Yet Recruiting | MAgnetic Resonance Imaging-guided implanTation of Cardioverter DEFibrillators NCT06269692 | Central Hospital, Nancy, France | N/A |
| Recruiting | Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2 NCT06025123 | Karolinska Institutet | N/A |
| Completed | Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study NCT05791032 | AtaCor Medical, Inc. | N/A |
| Recruiting | Epinephrine Dose: Optimal Versus Standard Evaluation Trial NCT03826524 | Unity Health Toronto | Phase 4 |
| Active Not Recruiting | Assessment of Combined CCM and ICD Device in HFrEF NCT05855135 | Impulse Dynamics | N/A |
| Unknown | VectOr ChAnge defibriLlatIon in Refractory Shockable rhyThms NCT05926973 | Thames Valley Air Ambulance | — |
| Recruiting | ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacin NCT06324682 | University Hospital of Ferrara | — |
| Withdrawn | Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT) NCT05236920 | University of Alabama at Birmingham | N/A |
| Recruiting | Development of CIRC Technologies NCT05654272 | The Cleveland Clinic | — |
| Unknown | Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest NCT05325385 | University Hospital Southampton NHS Foundation Trust | — |
| Unknown | Risk Stratification of VT / VF After Myocardial Infarction Based on Cardiac MRI 2 NCT05226234 | Central Hospital, Nancy, France | — |
| Completed | Sensing and Defibrillation With a Commercially Available ICD Coupled With a Parasternal Extravascular Lead (SE NCT05352776 | AtaCor Medical, Inc. | N/A |
| Completed | Parasternal Access for ShockS and Pacing With an acUtely Placed Less-invasive Lead for EV-ICD (PASS PULL EV-IC NCT05099289 | AtaCor Medical, Inc. | N/A |
| Unknown | GANGlion Stellate Block for Treatment of Electric storRm (GANGSTER Trial) NCT05078684 | Institute for Clinical and Experimental Medicine | Phase 3 |
| Unknown | Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias NCT01013714 | University of California, Los Angeles | Phase 3 |
| Unknown | Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Cardiopulmona NCT04392258 | Ruhr University of Bochum | — |
| Completed | Cardiac Rehab Retrospective Review (CR3) NCT04675957 | Medical University of Graz | — |
| Completed | Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm NCT04691089 | French Defence Health Service | — |
| Completed | Vektor vMap™ Clinical Validation Study NCT04559061 | Vektor Medical | — |
| Unknown | Gut Microbiome and Ventricular Arrhythmias NCT04466072 | North Florida Foundation for Research and Education | — |
| Unknown | Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective NCT04580992 | Universitair Ziekenhuis Brussel | — |
| Recruiting | A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation NCT04576130 | Rigshospitalet, Denmark | N/A |
| Unknown | Better Mechanistic Understanding of and Risk Stratification for Ventricular Tachyarrhythmias Through ECGI NCT04548804 | Maastricht University Medical Center | N/A |
| Completed | Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 ) NCT03700125 | Barts & The London NHS Trust | N/A |
| Completed | DOuble SEquential External Defibrillation for Refractory VF NCT04080986 | Sunnybrook Health Sciences Centre | N/A |
| Terminated | Advanced Reperfusion Strategies for Refractory Cardiac Arrest NCT03880565 | University of Minnesota | N/A |
| Terminated | Unpinning Termination Therapy for VT/VF NCT03871231 | Cardialen, Inc. | N/A |
| Terminated | Real Time Amplitude Spectrum Area to Guide Defibrillation NCT03237910 | Mario Negri Institute for Pharmacological Research | N/A |
| Unknown | Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrill NCT03963271 | Maastricht University Medical Center | — |
| Unknown | Post-marketing Registration Study of Nifekalant Hydrochloride (NIF) Injection NCT03853369 | Sichuan Baili Pharmaceutical Co., Ltd. | — |
| Unknown | Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection. NCT03855826 | Sichuan Baili Pharmaceutical Co., Ltd. | Phase 4 |
| Unknown | Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Res NCT03715556 | University of Sao Paulo General Hospital | Phase 3 |
| Completed | Acute Feasibility Investigation of a New S-ICD Electrode NCT03802110 | Boston Scientific Corporation | N/A |
| Completed | Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System. NCT04011631 | SMART Clinical Products BV | N/A |
| Completed | DOuble SEquential External Defibrillation for Refractory VF Pilot Study NCT03249948 | Sunnybrook Health Sciences Centre | N/A |
| Terminated | ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arres NCT03119571 | University of Minnesota | N/A |
| Recruiting | In-hospital Stellate Ganglion Block for Arrhythmic Storm NCT05720936 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Completed | Arrhythmias in Post-Myocardial Infarction Patients NCT03231826 | Tampere University | — |
| Completed | Emotional Regulation in Patients With Implanted Automatic Defibrillator NCT04235881 | Instituto de Investigación Hospital Universitario La Paz | N/A |
| Withdrawn | Effect of Right Ventricular Lead Position on Defibrillation Threshold NCT02844127 | OhioHealth | N/A |
| Unknown | International Electrical Storm Registry NCT02882139 | Università Politecnica delle Marche | — |
| Completed | Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death NCT03248557 | Hospital San Carlos, Madrid | — |
| Unknown | Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions NCT02982473 | Universitätsmedizin Mannheim | — |
| Completed | To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients NCT01665755 | Singapore General Hospital | N/A |
| Completed | Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction NCT02433379 | Boston Scientific Corporation | N/A |
| Completed | PREVENTION-ACHD Risk Score NCT03957824 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Austrian Wearable Cardioverter Defibrillator Registry NCT02816047 | Medical University of Graz | — |
| Completed | SD01 Registry (SD01 ICD Lead) NCT02014675 | Biotronik SE & Co. KG | — |
| Completed | Safety and Performance Study of the RELIANCE 4-Front Passive Fixation Lead NCT01856491 | Boston Scientific Corporation | N/A |
| Completed | Recognizing Ventricular Fibrillation From an Area of a Mobile Phone NCT01824212 | North Karelia Central Hospital | — |
| Unknown | Italian Registry On Multipoint Left Ventricular Pacing NCT02606071 | University of Rome Tor Vergata | — |
| Completed | SD01 Master Study (Safety and Efficacy Study) NCT01836497 | Biotronik SE & Co. KG | — |
| Unknown | A Feasibility Study on Prediction of an ICD Shock by ICD-derived Data NCT01822145 | Princess Margaret Hospital, Hong Kong | — |
| Completed | DF4 Master Study (Safety and Efficacy Study) NCT01790841 | Biotronik SE & Co. KG | — |
| Completed | The Use of Mobile Phones in Out of Hospital Cardiac Arrest to Increase Bystander CPR NCT01789554 | Karolinska Institutet | N/A |
| Completed | Physicians in Training and Critical Care Nurses Performance in Medical Code Events: Effect of Simulation-Based NCT02707185 | St. Luke's-Roosevelt Hospital Center | N/A |
| Completed | Circulating Biomarkers and Ventricular Tachyarrhythmia NCT01892462 | Ochsner Health System | — |
| Completed | Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defib NCT01594112 | Biotronik SE & Co. KG | — |
| Completed | DF4 Connector System Post-Approval Study NCT01638897 | Medtronic | — |
| Completed | The Leiden Nonischemic Cardiomyopathy Study NCT01940081 | Leiden University Medical Center | — |
| Completed | Study of the Wearable Defibrillator in Heart-Failure Patients NCT01326624 | Zoll Medical Corporation | — |
| Terminated | LifeVest Post-CABG Registry NCT01448005 | Zoll Medical Corporation | — |
| Completed | Evaluation of Depolarization and Repolarisation Activity During Cardiac Arrhythmia Using a Novel Monophasic Ac NCT01254474 | University Hospital, Bordeaux | N/A |
| Recruiting | Registry of Device Implantation NCT03360227 | Klinik für Kardiologie, Pneumologie und Angiologie | — |
| Unknown | Arrhythmia Genetics in the NEtherlandS NCT03007199 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Terminated | Influence of Mild Therapeutic Hypothermia on Leukocyte Count NCT00520520 | Charite University, Berlin, Germany | — |
| Completed | Shockless Implant Evaluation NCT00800384 | Boston Scientific Corporation | N/A |
| Completed | Comparison of Right Ventricular Septal and Right Ventricular Apical Pacing in Patients Receiving a CRT-D Devic NCT00833352 | Guidant Corporation | N/A |
| Completed | The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock NCT00787800 | Mayo Clinic | Phase 4 |
| Terminated | European Health Economic Trial on Home Monitoring in ICD and CRT-D Patients (EuroEco) NCT00776087 | Biotronik SE & Co. KG | N/A |
| Completed | Septal Positioning of Ventricular Implanted Cardioverter Defibrillator (ICD) Leads NCT00745745 | Abbott Medical Devices | N/A |
| Terminated | Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans NCT00846417 | Emory University | — |
| Completed | Vest Prevention of Early Sudden Death Trial and VEST Registry NCT01446965 | University of California, San Francisco | N/A |
| Completed | Feature Assessment Study for Indications Based Programming NCT00711893 | Boston Scientific Corporation | — |
| Completed | Medtronic Genetic Arrhythmia Markers for Early Detection (GAME Study) NCT00664807 | Medtronic Corporate Technologies and New Ventures | — |
| Completed | SAFEty of Two Strategies of ICD Management at Implantation NCT00661037 | Boston Scientific Corporation | — |
| Completed | Impact of Ventricular Pacing in Unselected ICD/CRT-D Patients NCT01169896 | LivaNova | — |
| Completed | Left Ventricular Capture Management Study NCT01089634 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Completed | Influence of Home Monitoring on the Clinical Status of Heart Failure Patients With an Impaired Left Ventricula NCT00538356 | Biotronik SE & Co. KG | Phase 4 |
| Completed | DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients. NCT00478933 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Unknown | DIagnostics, Fatty Acids and Vitamin D in SCA NCT02886273 | Helse Stavanger HF | — |
| Terminated | Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial NCT00401882 | David Haines, MD | Phase 2 |
| Completed | Benefits of Implantable Cardioverter Defibrillator Follow-up Using Remote Monitoring NCT00989417 | Biotronik SE & Co. KG | N/A |
| Completed | A Randomized Trial of Remote Monitoring of Implantable Cardioverter Defibrillators Versus Quarterly Device Int NCT00606567 | Duke University | N/A |
| Completed | Further Acute Research of a Subcutaneous Implantable Defibrillator (S-ICD) System NCT00399217 | Boston Scientific Corporation | — |
| Completed | CONNECT Study - Clinical Evaluation Of Remote NotificatioN to rEduCe Time to Clinical Decision NCT00402246 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Completed | Automatic External Defibrillation Monitoring in Cardiac Arrest NCT00382928 | Foundation for Atlanta Veterans Education and Research, Inc. | Phase 1 |
| Terminated | Pediatric Lead Extractability and Survival Evaluation (PLEASE) NCT00335036 | Charles Berul | N/A |
| Completed | SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival NCT00535106 | New York City Fire Department | N/A |
| Completed | Canadian Registry of ICD Implant Testing Procedures NCT00848341 | Guidant Corporation | — |
| Completed | First Arrhythmia Collection of Transvenous and Simultaneous Subcutaneous Implantable Defibrillator Data NCT01161589 | Boston Scientific Corporation | — |
| Completed | Medications and the Risk of Sudden Cardiac Death NCT00241800 | Vanderbilt University Medical Center | — |
| Completed | AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute" NCT00139542 | Fire Brigade Of Paris Emergency Medicine Dept | Phase 3 |
| Terminated | OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy D NCT00277524 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Completed | Double Blind Placebo Controlled Dose Ranging Study of the Efficacy and Safety of SSR149744c 100 or 300 mg for NCT00232297 | Sanofi | Phase 2 |
| Completed | Septal - Success Rate and Clinical Outcome of Septal Implant of Ventricular Defibrillation Lead NCT00180297 | Boston Scientific Corporation | N/A |
| Completed | Leader - Evaluation of Endotak Reliance NCT00180349 | Boston Scientific Corporation | — |
| Unknown | High Low Biphasic Energy Defibrillation (HiLoBED) NCT00429611 | Singapore General Hospital | Phase 3 |
| Completed | Safety and Efficacy Study of RENEWAL 4 AVT NCT00180336 | Boston Scientific Corporation | Phase 2 / Phase 3 |
| Completed | ADVANCE-D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (ICD) The NCT00147277 | Medtronic Cardiac Rhythm and Heart Failure | Phase 4 |
| Completed | ADVANCE CRT - D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (IC NCT00147290 | Medtronic Cardiac Rhythm and Heart Failure | Phase 4 |
| Completed | INSIGHTS ICD Registry NCT00279968 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Completed | Remote Follow-up of Patients Receiving Implantable Cardioverter Defibrillator for Prophylactic Therapy NCT00401466 | Biotronik SE & Co. KG | Phase 4 |
| Completed | MAVRIC VR ICD Registry NCT00270933 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Completed | DAVID II (Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial II) NCT00187187 | Abbott Medical Devices | N/A |
| Completed | Prognostic Significance of T Wave Alternans NCT00006501 | Columbia University | — |
| Completed | Electrophysiological Effects of Late PCI After MI NCT00119847 | University of Maryland, Baltimore | N/A |
| Completed | INSURE: INcidence Free SUrvival Before and After Implantable Cardioverter Defibrillator (ICD) Replacement NCT00180440 | Guidant Corporation | — |
| Completed | OPERA: French Observational Study on Patients Implanted With a Guidant PRIZM or Vitality Defibrillator NCT00180375 | Boston Scientific Corporation | — |
| Completed | VERRARI - "Are Ventricular Arrhythmic Episodes Reduced by Rate Response in ICDs?" NCT00180427 | Guidant Corporation | Phase 4 |
| Completed | DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study NCT00157820 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Completed | Public Access Defibrillation (PAD) Community Trial NCT00004560 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Fatty Acid Antiarrhythmia Trial (FAAT) NCT00004559 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Antiarrhythmic Effects of N-3 Fatty Acids NCT00004558 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation NCT00387803 | Boston Scientific Corporation | Phase 2 / Phase 3 |
| Completed | Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation NCT00173615 | National Taiwan University Hospital | — |
| Completed | Failure of Chronically Implanted Defibrillator Leads -Incidence and Management NCT00614718 | University Hospital, Basel, Switzerland | — |
| Completed | Antiarrhythmics Versus Implantable Defibrillators (AVID) NCT00000531 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Linkage Study of Long QT Syndrome In An Amish Kindred NCT00005250 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) NCT00000464 | University of Washington | Phase 3 |
| Completed | Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) NCT00000518 | University of Utah | Phase 3 |
| Completed | Evaluation of SC-V Versus Conventional CPR NCT00000502 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Beta-Blocker Heart Attack Trial (BHAT) NCT00000492 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Unknown | Out-of Hospital Resuscitation Study NCT00196248 | Deutsches Herzzentrum Muenchen | — |
| Unknown | Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological NCT00176176 | Heidelberg University | N/A |