NCT01446965

Vest Prevention of Early Sudden Death Trial and VEST Registry

Vest Prevention of Early Sudden Death Trial: Prevention of Sudden Death After Myocardial Infarction Using a LifeVest Wearable Cardioverter-defibrillator (Formerly VEST/PREDICTS)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,348 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study explores the hypothesis that wearable defibrillators can impact mortality by reducing sudden death during the first three months after a heart attack in persons with high risk for life-threatening arrhythmias.

Detailed description

In patients with ventricular dysfunction immediately following myocardial infarction, sudden death may be responsible for up to 50% of total mortality. Wearable defibrillators may reduce sudden death by providing immediate detection and treatment of ventricular arrhythmias. This study is design to demonstrate a reduction in sudden death measured at three months following myocardial infarction among patients who have ventricular dysfunction.

Conditions

• Myocardial Infarction
• Ventricular Dysfunction
• Sudden Death
• Ventricular Tachycardia
• Ventricular Fibrillation

Interventions

Type	Name	Description
DEVICE	wearable defibrillator	LifeVest wearable defibrillator

Timeline

• Start date: 2008-07-01
• Primary completion: 2019-05-31
• Completion: 2019-05-31
• First posted: 2011-10-05
• Last updated: 2021-01-20
• Results posted: 2021-01-20

Locations

71 sites across 3 countries: United States, Germany, Poland