Venous Leg Ulcer

149 registered clinical trials studyying Venous Leg Ulcer — 35 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers NCT06930768	NuScience Medical Biologics, LLC	N/A
Not Yet Recruiting	Evaluation of the Efficacy of Hyalomatrix® in the Healing of Chronic Venous Leg Ulcers NCT07335861	NuScience Medical Biologics, LLC	N/A
Not Yet Recruiting	Phase 1 Study of LUT017 Gel to Evaluate Safety and Wound Healing in Adults With Venous Leg Ulcers and Chronic NCT07463365	Antoni Ribas	Phase 1
Not Yet Recruiting	Effect of Photobiomodulation on Healing of Venous Leg Ulcers NCT07123285	University of Nove de Julho	N/A
Recruiting	A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental NCT07364630	BioLab Holdings	Phase 4
Not Yet Recruiting	Cold atmOspheric plaSMa Therapy Versus standArd Wound Care in Diabetic Foot and Venous Leg ulcerS NCT07251426	Olaf Bakker	N/A
Recruiting	PMCF Study of Debridement Pad NCT07255937	Advanced Medical Solutions Ltd.	N/A
Recruiting	CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations NCT07046767	Capsicure, LLC	N/A
Recruiting	Suprasorb®X+PHMB Pro vs Suprasorb®X+PHMB in Treatment of Infected Venous Leg Ulcers NCT07211243	Lohmann & Rauscher	N/A
Recruiting	Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Venous Leg Ulcers NCT07061613	NuScience Medical Biologics, LLC	N/A
Recruiting	Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care NCT07089602	BioLab Holdings	Phase 4
Not Yet Recruiting	COMS for Chronic Ulcers Treatment NCT06528873	Sebastian Probst	Phase 4
Completed	AQUACEL® Ag+ Extra™ vs Cutimed® Sorbact® NCT07308678	ConvaTec Inc.	—
Recruiting	Tissue Repair Gel in Venous Leg Ulcers in AU/US NCT06707103	TR Therapeutics	Phase 3
Recruiting	Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population NCT06544564	BioLab Holdings	N/A
Recruiting	Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC NCT06811909	BioStem Technologies	N/A
Recruiting	Tissue Repair Gel in Venous Leg Ulcers (US) NCT06707090	TR Therapeutics	Phase 3
Recruiting	Evaluating the Durability of Closure for Venous Leg Ulcers NCT06697925	Kerecis Ltd.	—
Active Not Recruiting	Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III) NCT06489028	RHEACELL GmbH & Co. KG	Phase 3
Recruiting	Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard NCT06826339	Tiger Biosciences, LLC.	Phase 4
Enrolling By Invitation	A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers NCT06453187	Integra LifeSciences Corporation	N/A
Completed	Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers NCT06562296	Cellution Biologics	Phase 4
Recruiting	INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone NCT06606210	ConvaTec Inc.	N/A
Recruiting	RCT Exudate Management Cutimed Sorbion Product Range NCT06300762	BSN Medical GmbH	N/A
Enrolling By Invitation	Kerecis Real-World Fish Skin Graft Registry NCT06384183	Kerecis Ltd.	—
Recruiting	Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs NCT06560502	Stability Biologics	N/A
Recruiting	Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Tre NCT06515093	Surgenex	N/A
Enrolling By Invitation	Clinical Registry Collecting Real World Evidence on Wound Care Treatments NCT06328010	Siddhey LLC	—
Completed	FORCEREPAIR - A Wound Exudate Investigation NCT06109844	Bispebjerg Hospital	—
Completed	Time to Heal (Wound, Healing, Dialogue, Nutrition) NCT06255288	Hvidovre University Hospital	N/A
Terminated	PICO Venous Leg Ulcers (VLU) Reimbursement Study NCT06510777	Smith & Nephew, Inc.	N/A
Unknown	The Impact of Frequenting a Social Leg Program on Therapeutic Adherence and Venous Leg Ulcer Wound Healing Out NCT04370106	School of Health Sciences Geneva	N/A
Unknown	Laser Therapy for Venous Leg Ulcers NCT06135246	Ahram Canadian University	N/A
Completed	Diagnostics in the Leg Ulcer Pathway NCT06181708	Imperial College London	—
Completed	Evaluation of the Efficacy of Multilayer Compression & UrgoStart Plus NCT06007703	Gloucestershire Hospitals NHS Foundation Trust	—
Unknown	Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION) NCT05772507	Laboratoires URGO	N/A
Recruiting	Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds NCT06236750	MiMedx Group, Inc.	N/A
Completed	Investigation of the Clinical Performance of Biatain Fiber Ag on Venous Leg Ulcers NCT05873257	Coloplast A/S	N/A
Completed	The Effect of Different Types of Music on Pain and Anxiety During Wound Care Procedures in Patients With Venou NCT07287254	Izmir Katip Celebi University	N/A
Active Not Recruiting	Air Cold Atmospheric Pressure Plasma Treatment for Acceleration of Venous Ulcer Healing NCT05894096	Clinica Universidad de Navarra, Universidad de Navarra	N/A
Completed	Preliminary Investigation of a Smart Compression Therapy Prototype NCT05610241	DeRoyal Industries, Inc.	N/A
Recruiting	The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study NCT05489588	W.L.Gore & Associates	N/A
Completed	Clinical Performance and Cost Effectiveness of Biatain® Silicone Compared With Standard of Care NCT05786612	Coloplast A/S	N/A
Completed	Intermittent Pneumatic Compression of the Thigh NCT05659394	Huntleigh Healthcare Ltd	N/A
Unknown	Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Ve NCT05707169	Mansoura University	N/A
Recruiting	Phase Ⅱ Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Venous Leg NCT05319106	ShiCang Yu	N/A
Completed	Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds NCT05619237	Chester Ho, MD	N/A
Completed	AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Perio NCT05892341	ConvaTec Inc.	N/A
Recruiting	A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam NCT05608317	Molnlycke Health Care AB	N/A
Recruiting	A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dre NCT05588583	Molnlycke Health Care AB	N/A
Recruiting	A Study of XSTEM-VLU in Patients With Difficult-to-heal Venous Leg Ulcers NCT05549609	Xintela AB	Phase 1 / Phase 2
Active Not Recruiting	The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study NCT05409976	W.L.Gore & Associates	N/A
Completed	Suprasorb® A + Ag in the Treatment of Wounds at Risk of Infection and Infected Wounds NCT05646121	Lohmann & Rauscher	—
Completed	Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous Leg Ulcers NCT05974982	Jinnah Postgraduate Medical Centre	Phase 1
Terminated	Efficacy Study for Geko Device in VLU Patients (Canada) NCT05057793	Firstkind Ltd	N/A
Unknown	A Study to Evaluate ENERGI-F703 GEL in Venous Leg Ulcer NCT04078555	Energenesis Biomedical Co., Ltd.	Phase 2
Unknown	Clinical Evaluation in Real Life of TLC-NOSF Dressings in the Local Treatment of Chronic Wounds (DFU and VLU) NCT06135987	Laboratoires URGO	—
Withdrawn	The Avelle® Negative Pressure Wound Therapy System on Chronic Wounds NCT05666570	ConvaTec Inc.	—
Unknown	DETEC® Esterase for Screening Wound Infection at Point of Care NCT04614870	Progenitec Inc.	—
Completed	Omeza Combination Therapy With Standard of Care to Standard of Care Alone for Chronic Venous Leg Ulcers NCT05291169	Omeza, LLC	N/A
Active Not Recruiting	Geko™ Cross Therapy Registry - Wound NCT05007301	Firstkind Ltd	—
Recruiting	MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers NCT04647240	Merakris Therapeutics	Phase 2
Unknown	Combined Electromagnetic Field and a Plantar Resistance Exercise With Venous Leg Ulcer NCT05410613	Mona Mohamed Taha	N/A
Completed	ChitoCare Medical Wound Healing Gel PMCF Study on Healing of Chronic Wounds NCT05570877	Primex ehf	N/A
Unknown	DETEC® pH Point of Care Wound Diagnostic Test NCT04614038	Progenitec Inc.	—
Terminated	An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a NCT05494450	Molnlycke Health Care AB	N/A
Completed	Efficacy and Safety of URGOBD001 Compression System NCT05158764	Laboratoires URGO	N/A
Unknown	Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in NCT05165459	Szeged University	N/A
Recruiting	Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center NCT04920253	Medaxis, LLC	N/A
Completed	Lymphovenous Bypass Manage Venous Leg Ulcers NCT05068258	National Taiwan University Hospital	N/A
Completed	Safety and Tolerability of Single and Multiple Doses of SoftOx Biofilm Eradicator (SBE) in Chronic Leg Wounds NCT05710094	SoftOx Solutions AS	Phase 1
Unknown	Clinical Investigation of Sorbact® Dressings NCT05089890	ABIGO Medical AB	N/A
Completed	Clinical Trial Enzyme Application Targeting Venous Leg Ulcers NCT04956900	SolasCure Limited	Phase 2
Terminated	Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Di NCT04927702	Acera Surgical, Inc.	N/A
Completed	Confirm Safety and Performance of Avance Solo and Avance Solo Adapt NPWT Systems NCT04753294	Molnlycke Health Care AB	N/A
Unknown	Clinical Study Of Affinity Versus SOC In The Management Of VLUs NCT04901013	Organogenesis	N/A
Terminated	PLASOMA Efficacy & Technology Health (PETH) Study NCT04922463	Plasmacure	N/A
Completed	PLASOMA Ultimate Safety & Efficacy Study NCT04828304	Plasmacure	N/A
Unknown	HM242-Solution vs Comparator NCT04902612	B. Braun Ltd. Centre of Excellence Infection Control	N/A
Terminated	HM242-Gel vs Comparator NCT04902651	B. Braun Ltd. Centre of Excellence Infection Control	N/A
Completed	A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lowe NCT04817228	MediWound Ltd	Phase 2
Unknown	Effect of rhGM-CSF on the Healing of Venous Leg Ulcers NCT04823962	Reponex Pharmaceuticals A/S	Phase 2
Recruiting	Finnish Venous Ulcer Study (FINNULCER Study) NCT04737941	Oulu University Hospital	N/A
Completed	Feasibility and Tolerance Study for the Treatment of Varicose Ulcers by Cyanoacrylate Glue (ETUVVE) NCT04714749	Clinique Pasteur	N/A
Unknown	Gene Expression in Chronic Venous Leg Ulcers NCT05134597	University of Catanzaro	—
Unknown	Helium Neon Laser Versus Gallium Arsenide Laser NCT04689620	Mahmoud Awad Ramadan Elkholy	N/A
Unknown	Efficacy and Safety of a New Compression System URGO BD001 in the Treatment of VLU (FREEDOM) NCT04613687	Laboratoires URGO	N/A
Terminated	A Multicentre European Study to Evaluate Granulox® Used in the Treatment Pathway of Predominantly Chronic Veno NCT04181320	Molnlycke Health Care AB	N/A
Unknown	The Omeza Protocol for Chronic Ulcers NCT04198441	Omeza, LLC	N/A
Completed	The Impact of a Pluridisciplinary Education Program on Venous Leg Ulcer Size Reduction NCT04019340	School of Health Sciences Geneva	N/A
Terminated	Debritom - Micro Water Jet Technology and Wound Healing NCT04240574	Stephanie Wu	N/A
Completed	Differential Effects of Bacteria Colonising Venous Leg Ulcers on Pain and Healing Rates NCT04249661	University Hospital of Limerick	—
Completed	A Study to Evaluate the Safety and the Efficacy of EscharEx (EX-02 Formulation) in Debridement of Venous Leg U NCT03588130	MediWound Ltd	Phase 2
Terminated	A Comparative Evaluation of a MPS Dressing and a CMC Dressing on Subjects With Lower Extremity Venous Ulcers NCT03903692	Medline Industries	N/A
Completed	Cyanoacrylate Closure for Treatment of Venous Leg Ulcers NCT04011371	Sunnybrook Health Sciences Centre	N/A
Unknown	DEep VEin Lesion OPtimisation (DEVELOP) Trial NCT03640689	National University of Ireland, Galway, Ireland	N/A
Withdrawn	Evaluation of Cirvo™ Mobile Compression Device for Treatment of Venous Leg Ulcers NCT03544788	Radial Medical, Inc.	N/A
Withdrawn	Pilot Study Comparing Negative Pressure Dressings to Conventional Dressings NCT03450616	Northwell Health	N/A
Unknown	Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulc NCT03667937	University of Malaga	Phase 4
Completed	Leg Ulcers Standards of Care Enhancement NCT04689009	Emoled	N/A
Unknown	Impact of Venotrain UlcerteC Venous Compression Device in the Treatment of Venous Ulcers in Daily Practice NCT03736941	Fondation Hôpital Saint-Joseph	N/A
Completed	SkinTE® in the Treatment of Venous Leg Wounds NCT03881267	PolarityTE	N/A
Completed	Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds NCT03662997	Molnlycke Health Care AB	N/A
Active Not Recruiting	Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers NCT03796793	University of Miami	N/A
Completed	Subjects With Non-Healing Venous Leg Ulcers Treated With Standard Care Plus Cryopreserved Human Umbilical Cord NCT03818828	BioTissue Holdings, Inc	Phase 2
Completed	DermaRep™ Device in the Treatment of Venous Leg Ulcers NCT03699072	Biovotec AS	N/A
Unknown	Management of Infection Risk in Non-comparative Trial (MINT) NCT03670329	Laboratoires URGO	N/A
Unknown	Early Glue Saphenous Vein Ablation With Compression Versus Compression Alone in the Healing of the Venous Ulce NCT03666754	Mahidol University	N/A
Completed	The Effect of Manual Lymphatic Drainage NCT04461132	Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey	N/A
Completed	VLU Dressing Study NCT03621592	University of Miami	N/A
Recruiting	Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers NCT03716167	Wake Forest University Health Sciences	N/A
Terminated	A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in El NCT04577183	RedDress Ltd.	N/A
Unknown	Assessment of the Evolution of Wound Biomarkers in Venous Leg Ulcers Treated With KLOX Biophotonic System NCT03593369	KLOX Technologies Inc.	N/A
Active Not Recruiting	Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial) NCT03250247	Washington University School of Medicine	N/A
Completed	Study to Evaluate Safety and Efficacy of GrafixPL for the Treatment of Venous Leg Ulcers NCT03629236	Osiris Therapeutics	N/A
Completed	Clinical Effectiveness of DermACELL AWM in Subjects With Chronic Venous Leg Ulcers NCT03589586	LifeNet Health	N/A
Completed	Efficacy Study for Geko Device in VLU Patients NCT03396731	Firstkind Ltd	N/A
Completed	Electrostimulation in Patients with Leg Ulcers NCT06849024	Centro Universitario de Tonalá	N/A
Completed	Pressure and Temperature Sensor for Therapeutic Compression Garments NCT03461549	Northwestern University	—
Unknown	Non Contrast MRI in Lower Extremity NCT04995432	Chang Gung Memorial Hospital	—
Completed	DURAFIBER Ag Post-Market Clinical Follow-Up NCT03277131	Smith & Nephew, Inc.	N/A
Completed	Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU) NCT03257254	Boston Scientific Corporation	—
Completed	Dose-response Relationship Study of S42909 on Leg Ulcer Healing NCT03077165	Ilkos Therapeutic Inc.	Phase 2
Withdrawn	Intermittent Pneumatic Compression of the Foot vs Geko Plus R-2 Neuromuscular Electrostimulation Device in Ven NCT02912858	Firstkind Ltd	N/A
Withdrawn	Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs NCT02988063	OhioHealth	Phase 4
Withdrawn	A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patient NCT01982318	Tissue Therapies Ltd.	Phase 2 / Phase 3
Active Not Recruiting	Efficacy of TR 987, Beta-1,3-1,6-D-glucan, in the Treatment of Chronic Venous Insufficiency Ulcers NCT03154619	SerenaGroup, Inc.	Phase 2
Completed	Investigation to Evaluate the Efficacy and Safety of Exufiber Versus Aquacel Extra in Moderately or Strongly E NCT02921750	Molnlycke Health Care AB	N/A
Completed	Geko Venous Leg Ulcer Study NCT02482038	Firstkind Ltd	N/A
Completed	A Study in Patients With Venous Leg Ulcers and Measuring the Effects of Using Geko™ Device NCT02884323	Firstkind Ltd	N/A
Terminated	VLU Non-Inferiority Study Comparing a Dual Action Pneumatic Compression Device to Multi-Layer Bandaging NCT02680834	Tactile Medical	N/A
Completed	EUREKA Italy - Evaluation of Real-life Use of KLOX BioPhotonic System in Chronic Wounds Management NCT03021811	KLOX Technologies Inc.	N/A
Completed	Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers NCT02652572	Xequel Bio, Inc.	Phase 1
Terminated	Aspirin for Venous Ulcers: Randomised Trial (AVURT) NCT02333123	St George's, University of London	Phase 2
Completed	Low Dose Aspirin for Venous Leg Ulcers NCT02158806	University of Auckland, New Zealand	Phase 3
Completed	Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ul NCT02395302	Tactile Medical	N/A
Terminated	Clinical Study to Assess Efficacy and Safety of a New Compression System in the Management of Venous Leg Ulcer NCT02782689	Thuasne	N/A
Completed	Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison o NCT02104180	Mylan Inc.	N/A
Terminated	A Cohort Trial Comparing AutoloGel Therapy to Usual and Customary Care in Venous Leg Ulcers NCT01817543	Cytomedix	N/A
Completed	Early Venous Reflux Ablation Ulcer Trial NCT03286140	Imperial College London	N/A
Unknown	Safety Study Providing 12 Months Follow-up From First Exposure to HP802-247 in Subjects With Venous Leg Ulcer NCT01658618	Healthpoint	—
Completed	Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous NCT01552447	MiMedx Group, Inc.	N/A
Unknown	Trial of Compassionate Use of hp802-247 to Treat Venous Leg Ulcers in Subjects Who Have Failed Multiple Other NCT01320605	Atlantic Health System	Phase 2
Completed	Long-Term Follow-Up to the DEVO Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers NCT01891760	Shire Regenerative Medicine, Inc.	Phase 3
Completed	Trial on the Efficacy of Prontosan Wound Irrigation Solution and Prontosan Wound Gel NCT01153633	B. Braun Ltd. Centre of Excellence Infection Control	Phase 4
Completed	Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers NCT00909870	Organogenesis	Phase 3
Completed	Safety Follow-Up to HP 802-247-09-015 NCT00900029	Healthpoint	—
Completed	Dose Finding Study of HP802-247 in Venous Leg Ulcers NCT00852995	Healthpoint	Phase 2
Completed	Evaluation of Bilayered Cellular Matrix (OrCel) for the Treatment of Venous Ulcers NCT00270946	Ortec International	N/A