Clinical Trials Directory

Trials / Completed

CompletedNCT04249661

Differential Effects of Bacteria Colonising Venous Leg Ulcers on Pain and Healing Rates

Status
Completed
Phase
Study type
Observational
Enrollment
100 (actual)
Sponsor
University Hospital of Limerick · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This Study aims to identify whether venous leg ulcers which are colonised by Pseudomonas Aeruginosa cause more pain than those which are not and if this bacteria affects healing time. This may determine how venous ulcer infections are treated in order to improve symtomatology and quality of life for patients with these chronic wounds.

Detailed description

Pseudomonas is a gram-negative bacillus which commonly colonises lower limb venous ulcers. It produces exotoxins and elastase as well as forming biofilms within chronic wounds. Its effects on venous ulcer healing are debated. The objective of this study is to examine the effects on Pseudomonas Aeruginosa colonisation on the pain expereinces and healing rates of venous leg ulcers.

Conditions

Timeline

Start date
2020-01-09
Primary completion
2023-12-14
Completion
2023-12-14
First posted
2020-01-31
Last updated
2023-12-15

Locations

1 site across 1 country: Ireland

Source: ClinicalTrials.gov record NCT04249661. Inclusion in this directory is not an endorsement.