| Recruiting | A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation R NCT06671015 | Yale University | N/A |
| Withdrawn | Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Re NCT05884411 | VA Office of Research and Development | N/A |
| Recruiting | Neuromodulation of Inflammation and Endothelial Function NCT05230732 | University of Oklahoma | N/A |
| Completed | Effects of Postural Balance Exercises in Patients With Heart Failure NCT04937790 | Giresun University | N/A |
| Enrolling By Invitation | A Registry-based Cluster Randomized Trial to Compare the Effect of Spironolactone vs. Eplerenone on Clinical O NCT03984591 | Bispebjerg Hospital | Phase 4 |
| Completed | Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchro NCT04065893 | Universitätsklinikum Köln | — |
| Unknown | Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure NCT03871699 | Hospital Moinhos de Vento | Phase 4 |
| Suspended | How is COGNItive Function Affected by Cardiac Resynchronisation Therapy? NCT03755570 | Royal Cornwall Hospitals Trust | — |
| Completed | Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI) NCT04019314 | Mayo Clinic | N/A |
| Terminated | ECG for Programming in CRT NCT03936608 | Washington University School of Medicine | N/A |
| Terminated | Iron in Patients With Cardiovascular Disease NCT03991000 | Dr. med. Mahir Karakas | Phase 3 |
| Unknown | Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Reduced Ejection Fraction NCT03041610 | Charles University, Czech Republic | N/A |
| Unknown | Effectiveness of a Repetitive Use of 24-hour Levosimendan Infusions in Patients With Severe Systolic Heart Fai NCT03764722 | Collegium Medicum w Bydgoszczy | Phase 4 |
| Completed | Study of Dapansutrile Capsules in Heart Failure NCT03534297 | Olatec Therapeutics LLC | Phase 1 |
| Completed | Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart) NCT03446313 | University of California, San Francisco | N/A |
| Completed | Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality NCT03036462 | Universitätsklinikum Hamburg-Eppendorf | Phase 4 |
| Terminated | My Research Legacy Pilot Study NCT02958098 | American Heart Association | — |
| Completed | Junctional AV Ablation in CRT-D: JAVA-CRT NCT02946853 | University of Rochester | N/A |
| Unknown | GutHeart: Targeting Gut Microbiota to Treat Heart Failure NCT02637167 | Oslo University Hospital | Phase 2 |
| Unknown | Manipal Heart Failure Registry (MHFR) NCT03157219 | Manipal University | — |
| Unknown | Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidis NCT02316743 | Université de Sherbrooke | Phase 4 |
| Completed | Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy NCT01640769 | Libin Cardiovascular Institute of Alberta | N/A |
| Completed | A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs) NCT02026102 | University of Colorado, Denver | N/A |
| Completed | A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart Failure NCT02084992 | Tufts Medical Center | N/A |
| Completed | Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure Patients NCT02156583 | Thomas Jefferson University | — |
| Completed | Platelet Inhibition in Patients With Systolic Heart Failure NCT01765400 | University of Nebraska | Phase 4 |
| Completed | Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory Support NCT01932294 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failure NCT01814319 | University of Cincinnati | Phase 2 |
| Terminated | MIRACLE EF Clinical Study NCT01735916 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Completed | Bilateral Surgical Resection of Carotid Bodies in Patients With Systolic Heart Failure NCT01782677 | Noblewell | N/A |
| Completed | Effect of Nitrate-rich Beetroot Juice on Exercise Performance in Heart Failure Patients NCT02223403 | Brooke Army Medical Center | N/A |
| Completed | Surgical Removal of Carotid Body in Patients With Systolic Heart Failure NCT01653821 | Noblewell | N/A |
| Unknown | Reversal of Cardiomyopathy by Suppression of Frequent Premature Ventricular Complexes NCT01566344 | Maastricht University Medical Center | N/A |
| Terminated | Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systo NCT01646515 | Seoul National University Hospital | Phase 3 |
| Completed | Spinal Cord Stimulation For Heart Failure NCT01362725 | Abbott Medical Devices | Phase 2 / Phase 3 |
| Completed | Heart Failure (HF) Outpatient Monitoring Evaluation (HOME) Study NCT01347567 | Alere San Diego | N/A |
| Completed | Hair Cortisol and Testosterone in Heart Failure NCT01139697 | Meir Medical Center | — |
| Withdrawn | Pilot Study Using Echocardiography to Evaluate Patients With Heart Failure and Dyssynchrony Who Have a CRT-D D NCT01127334 | University of Mississippi Medical Center | — |
| Completed | Clinical Value of Heart Rate Variability Indexes to Predict Outcomes After Exercise Training in Chronic Heart NCT02903225 | Universidad de la Republica | Phase 4 |
| Unknown | DECIDE-HF: Heart Rate Variability in Heart Failure Patients NCT00949676 | Medtronic BRC | — |
| Completed | Comparison of Right Ventricular Septal and Right Ventricular Apical Pacing in Patients Receiving a CRT-D Devic NCT00833352 | Guidant Corporation | N/A |
| Completed | Psychosocial Patterns and Prognosis in Patients With Heart Failure NCT00709241 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Surgical Sympathetic Blockade in Heart Failure NCT01224899 | University of Sao Paulo | Phase 1 |
| Unknown | Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy NCT00348530 | Medical University of Silesia | Phase 4 |
| Unknown | Essential Hypotension and Allostasis Registry NCT02018497 | CES University | — |