Trials / Completed
CompletedNCT04065893
Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 65 (actual)
- Sponsor
- Universitätsklinikum Köln · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
Cardiac resynchronization therapy reduces mortality in patients with systolic heart failure and left bundle branch block. Reduced biventricular pacing can lead to therapy failure. Most effective mortality reduction was seen with a BiV pacing above 98%. Reduced BiV pacing is a common phenomenon with potential impact on CRT-response and pts' prognosis. Frequent ventricular ectopy may be associated with attenuated benefit from CRT. The investigators sought to systematically assess the effect of ventricular arrhythmia treatment on BiV pacing.
Conditions
- Systolic Heart Failure
- Ventricular Premature Complexes
- Ventricular Tachycardia
- Cardiac Resynchronization Therapy
- Reduced Biventricular Pacing
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Catheter ablation of ventricular arrhythmia | PVC or VT ablation |
| DRUG | Intensified medical therapy | Dosage increase / new onset of Betablocker / medical antiarrhythmic medication according to guideline and clinical practice |
Timeline
- Start date
- 2020-09-01
- Primary completion
- 2021-08-01
- Completion
- 2021-08-01
- First posted
- 2019-08-22
- Last updated
- 2021-11-15
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT04065893. Inclusion in this directory is not an endorsement.