| Not Yet Recruiting | Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial NCT07314957 | University of Zadar | N/A |
| Not Yet Recruiting | A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems NCT07323563 | RAI Services Company | N/A |
| Not Yet Recruiting | Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking: A Randomized NCT07459621 | Kaiser Permanente | N/A |
| Not Yet Recruiting | Abuse Liability for Eight Electronic Nicotine Products NCT07323511 | RAI Services Company | N/A |
| Recruiting | Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability NCT07476144 | JT International SA | Phase 1 |
| Recruiting | Smoking Cessation Before Bronchoscopy or CT-guided Puncture NCT07322796 | RWTH Aachen University | — |
| Not Yet Recruiting | Abuse Liability for Four Heated Tobacco Product (HTP) Consumables and Two HTP Devices NCT07267195 | RAI Services Company | N/A |
| Recruiting | Abuse Liability for Five Modern Oral Nicotine Products NCT07132814 | RAI Services Company | N/A |
| Recruiting | ACT Lung Health Intervention: Phase Two NCT06945120 | Dana-Farber Cancer Institute | N/A |
| Not Yet Recruiting | Therapeutic Contact Intensity in a Psychological Smoking Cessation Intervention With an App NCT06900985 | University of Santiago de Compostela | N/A |
| Recruiting | Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand NCT07102082 | Roswell Park Cancer Institute | N/A |
| Recruiting | Vape Use Among Younger & Older Smokers NCT07214168 | Abramson Cancer Center at Penn Medicine | — |
| Active Not Recruiting | An Experimental Evaluation of Menthol-Flavored Tobacco Accessories NCT07092501 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | Impact of Smoking on Physical Activity Level in Young Adults NCT07043920 | Saglik Bilimleri Universitesi | — |
| Completed | Effects of E-Cigarette Use on Oxidative Stress and Matrix Degradation NCT07338318 | Ankara Medipol University | — |
| Completed | Tobacco/Nicotine Purchase Patterns Across SES NCT06795997 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home NCT06693700 | Memorial Sloan Kettering Cancer Center | N/A |
| Completed | Effective Ads for Quitting Smoking NCT06485479 | UNC Lineberger Comprehensive Cancer Center | N/A |
| Recruiting | Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction NCT06077240 | Yale University | N/A |
| Recruiting | Switch or Quit R01 NCT06373679 | Medical University of South Carolina | N/A |
| Recruiting | rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings NCT06228235 | West Virginia University | N/A |
| Completed | Human Perception of Odors and Odor Blockers NCT06191419 | Tim McClintock | N/A |
| Recruiting | A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse NCT06118502 | Medical University of South Carolina | N/A |
| Active Not Recruiting | An Interactive Smartphone Application to Motivate Smokers to Quit NCT05799625 | Ottawa Heart Institute Research Corporation | N/A |
| Completed | Translational Research Center in Lung Cancer Disparities (TRACER) Project 2 NCT05490251 | Virginia Commonwealth University | — |
| Unknown | It´s Up To You: Update and Digitalization of a Universal School-based Prevention Intervention for Drug Initiat NCT05950074 | Instituto Europeo de Estudios en Prevención | N/A |
| Active Not Recruiting | Smoking Pattern and Influencing Factors in Hospitalized Patients NCT05959512 | Beijing Normal University | — |
| Recruiting | Take A Break - Rural NCT05790486 | Wake Forest University Health Sciences | N/A |
| Unknown | Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan NCT05484505 | Nazarbayev University | EARLY_Phase 1 |
| Recruiting | Overcoming Nicotine Dependence to Enable Quitting NCT05513872 | Rush University Medical Center | Phase 1 / Phase 2 |
| Recruiting | Health Opportunities and Promoters of Equitable Screening for Lung Cancer NCT05784922 | Massachusetts General Hospital | — |
| Unknown | The Effect of Telephone-Assisted Smoking Cessation Program in Patients Diagnosed With Non-Muscle Invasive Blad NCT05704231 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Completed | Acceptance and Usability of an App Promoting Healthy Behaviours Amongst Young Women at Increased Risk of Breas NCT05460650 | University of Manchester | N/A |
| Enrolling By Invitation | The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluatio NCT05554120 | Maastricht University Medical Center | — |
| Completed | Messages About Reduced Nicotine in Combusted Tobacco Products NCT05506046 | Georgia State University | N/A |
| Unknown | "Juego de LLaves": Study Protocol of a Universal School-based Drug Use Prevention Program (PSIDUP) NCT05442294 | Susana Al-Halabí | N/A |
| Completed | mMe: Motivational Monitoring to Enhance Smoking Cessation Among Cancer Patients NCT05370859 | University of Virginia | — |
| Completed | AAT + tDCS to Reduce Cue-induced Craving and Smoking Behavior NCT05426460 | Cynthia Conklin | N/A |
| Completed | CSD210903: A Study to Determine Subject Puffing Patterns of a Heated Tobacco Product With Four Non-Combusted C NCT05307822 | RAI Services Company | N/A |
| Recruiting | Smoke Free SafeCare: Establishing a Smoke Free Home in CPS-involved Families NCT05000632 | Georgia State University | N/A |
| Completed | CSD201201: Study to Assess Elements of Abuse Liability for Electronic Nicotine Delivery System P12 NCT05210699 | RAI Services Company | N/A |
| Unknown | Smoking Prevention Program in Poland NCT05488743 | Wroclaw Medical University | — |
| Completed | Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure NCT05157048 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | Impact of Nicotine Messaging on Beliefs and Behavior NCT05108649 | Andrew Strasser | N/A |
| Completed | Supporting Smoke-Free Policy Compliance in Public Housing NCT05016505 | Columbia University | N/A |
| Completed | "Natural" and "Organic" Cigarette Descriptors: Association With Expectancies, Subjective Effects, Topography, NCT05468333 | University of Nevada, Reno | N/A |
| Active Not Recruiting | Data Health VET - Data-driven Health Promotion at Vocational Education and Training Schools NCT05308459 | Steno Diabetes Center Copenhagen | N/A |
| Completed | CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted NCT05114863 | RAI Services Company | N/A |
| Unknown | Nurse-led Smoking Cessation Program With Follow-up in Healthy Life Centres: a Randomized Clinical Trial NCT05049174 | Vestre Viken Hospital Trust | N/A |
| Completed | Cigarette Smoking Among Young Adults NCT04340947 | University of Oklahoma | N/A |
| Terminated | Heat-not-burn Tobacco Product to Aid in Switching From Combustible to Noncombustible Nicotine (IQOS) NCT04861428 | University of Pittsburgh | N/A |
| Unknown | Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana NCT04891939 | Ghana Health Services | N/A |
| Completed | Switching to Potential Reduced Exposure Products in Adult Smokers NCT04250727 | Yale University | N/A |
| Completed | Clinical Learning Study for a Mobile Smoking Cessation Program NCT04857515 | Click Therapeutics, Inc. | — |
| Completed | Nurse-led Smoking Cessation With Further Follow-up in Lifestyle Centres - a Randomized Pilot Study NCT04772144 | Vestre Viken Hospital Trust | N/A |
| Completed | CSD210202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems NCT04751461 | RAI Services Company | N/A |
| Active Not Recruiting | Digitally Enhanced Smoking Cessation for High Risk Smokers NCT04691297 | Dana-Farber Cancer Institute | N/A |
| Completed | Health Education and Counseling in Smoking Cessation Behavior, Smoking Decisional Balance, and Self-efficacy NCT05905666 | Taipei Medical University WanFang Hospital | N/A |
| Completed | Smoking Cessation Pilot for People Living With HIV (PLWH) NCT04808609 | Columbia University | N/A |
| Completed | Impact of Smoking and Nicotine on the Risk of Being Infected With COVID-19 NCT04429815 | Central Hospital, Nancy, France | — |
| Completed | C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH) NCT04358705 | Case Comprehensive Cancer Center | N/A |
| Completed | CSD190601: A Study to Determine Subject Puffing Patterns of Electronic Nicotine Delivery Systems in an Ambulat NCT04308434 | RAI Services Company | N/A |
| Completed | CSD190401: A Study to Assess Elements of Abuse Liability for Nicotine-containing Pouch Tobacco Products NCT04372290 | RAI Services Company | N/A |
| Completed | Interventions to Help More Low-income Smokers Quit NCT04311983 | Washington University School of Medicine | N/A |
| Completed | Assessment of Smoking, Vaping, and Alcohol Consumption Behavior NCT04150510 | Pennington Biomedical Research Center | — |
| Completed | Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation NCT03083353 | University of Texas at Austin | EARLY_Phase 1 |
| Completed | A Focus Group Study to Explore Smoking Triggers and Acceptability of Just-in-time Adaptive Intervent NCT05231421 | University of Colorado, Denver | — |
| Completed | CSD190501: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambul NCT04226404 | RAI Services Company | N/A |
| Completed | Varenicline Light Smoking Pilot NCT04089982 | Duke University | Phase 4 |
| Completed | CSD190203: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambul NCT04104152 | RAI Services Company | N/A |
| Completed | Assessment of the Pivot Breath Sensor: Single-Arm Cohort Study NCT04133064 | Jennifer Marler, MD | N/A |
| Completed | Effects of E-Cigarettes in Menthol Smokers NCT05949034 | University of Southern California | N/A |
| Completed | Couples Dynamics and Smoking Cessation NCT03885336 | University of Southern California | — |
| Completed | Effect of Oral pH Changes on Smoking Desire NCT04032236 | Dokuz Eylul University | N/A |
| Completed | Development, Implementation, and Evaluation of School-based Smoking Prevention Education Program Among Non-smo NCT04036474 | National University of Singapore | N/A |
| Completed | Post-Market Surveillance of Tobacco Products NCT04255459 | RAI Services Company | N/A |