| Recruiting | Fatigue in Sjögren's Syndrome: 3 Therapeutic Strategies NCT06875102 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Recruiting | TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE NCT07153276 | University of Sao Paulo General Hospital | Phase 4 |
| Not Yet Recruiting | Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases NCT07301164 | Peking University Third Hospital | EARLY_Phase 1 |
| Recruiting | AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Ritux NCT06991114 | Artiva Biotherapeutics, Inc. | Phase 2 |
| Recruiting | Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases NCT06828042 | Peking University Third Hospital | Phase 1 / Phase 2 |
| Active Not Recruiting | Photodynamic Treatment as Part of Oral Healthcare on Persons With Sjögren's Syndrome NCT06877546 | Koite Health Oy | N/A |
| Completed | Temporomandibular Joint Dysfunction in Sjögren's Syndrome NCT07248306 | Pamukkale University | — |
| Completed | "Validity and Reliability of Pelvic Floor Distress Inventory-20 in Primary Sjögren's Syndrome" NCT07248436 | Pamukkale University | — |
| Not Yet Recruiting | Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined with Immunosuppressants in the Treatment of R NCT06821659 | Peking University Third Hospital | Phase 1 / Phase 2 |
| Enrolling By Invitation | "Core Stabilization Strenght and Pelvic Floor Functions in Primary Sjogren's" NCT06879444 | Pamukkale University | — |
| Recruiting | BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases NCT06794008 | Peking University People's Hospital | Phase 2 |
| Not Yet Recruiting | Ultrasonic COmparison of Salivary Glands in Autoimmune Diseases (COUGAR) NCT06680310 | University Hospital, Brest | — |
| Completed | Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Treatment Method for Sjogren's Syndrome (SS) NCT06626477 | Abilion Medical Systems AB | N/A |
| Recruiting | Rare AutoImmune SElf-management Programme Development NCT06642870 | University of the West of England | — |
| Active Not Recruiting | Comparing Efficacy of Autologous Serum Eye Drops With and Without Insulin in Autoimmune Dry Eye: A Randomized NCT06931041 | Instituto de Oftalmología Fundación Conde de Valenciana | Phase 3 |
| Recruiting | Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimm NCT07249060 | Hospital Universitario Araba | — |
| Active Not Recruiting | Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome NCT05349214 | Novartis Pharmaceuticals | Phase 3 |
| Active Not Recruiting | Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome NCT05350072 | Novartis Pharmaceuticals | Phase 3 |
| Completed | Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships NCT05124925 | Novartis Pharmaceuticals | Phase 2 |
| Terminated | A Study to Evaluate the Safety, Tolerability and Efficacy of MHV370 in Participants With Sjogren's Syndrome (S NCT04988087 | Novartis Pharmaceuticals | Phase 2 |
| Completed | The Feasibility of Multispectral Optoacoustic Tomography in Different Diseases NCT06740175 | University Medical Center Groningen | N/A |
| Recruiting | Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorde NCT03816345 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndro NCT03865888 | Pavly Moawd | Phase 3 |
| Unknown | Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis NCT03839069 | National Taiwan University Hospital | N/A |
| Withdrawn | Pregnancy and Medically Assisted Conception in Rare Diseases NCT02450396 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye NCT02257957 | Universidad Nacional de Colombia | Phase 3 |
| Completed | Green Tea Lozenges for the Management of Dry Mouth NCT01647737 | Augusta University | Phase 1 / Phase 2 |
| Completed | Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops NCT01850979 | University of Sao Paulo General Hospital | Phase 4 |
| Unknown | Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular Dysfunction NCT02132585 | University of Roma La Sapienza | — |