NCT02257957

Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Universidad Nacional de Colombia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Dry eye is a chronic condition that decreases function and affect visual function with severe discapacity until now treatments are based in artificial eye drops. Platelet rich plasma has emerged as a strategy for cellular restoration, the purpose of this study is to evaluate their effects in lacrimal production and safety of this intervention in patients with severe dry eye.

Detailed description

Dry eye is a chronic condition that decreases function and affect visual function with severe discapacity until now treatments are based in artificial eye drops. Platelet rich plasma has emerged as a strategy for cellular restoration, the purpose of this study is to evaluate their effects in lacrimal production and safety of this intervention in patients with severe dry eye.

Conditions

• Dry Eye
• Sjogren Syndrome

Interventions

Type	Name	Description
DRUG	PRP injection
DRUG	Standard care Hyaluronic acid eye drops	: 15 patients with diagnosis of severe dry eye will receive standard of care treatment ( Hyaluronic acid eye drops 5 times per day). Objective measurements as corneal staining, Shirmer , BUT, and VA, will be determinate as subjective measurements as OSDI and treatment compliance will be evaluated at day 0-30,60 and 90

Timeline

• Start date: 2014-11-30
• Primary completion: 2015-09-30
• Completion: 2016-04-20
• First posted: 2014-10-07
• Last updated: 2021-08-24
• Results posted: 2021-08-24