Clinical Trials Directory

Trials / Completed

CompletedNCT05124925

Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.

An Open-label, Non-randomized, Biopsy-based Mechanistic Study on Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Ianalumab in Patients With Sjögren's Syndrome

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
21 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

This study aims at elucidating the mechanism of action of ianalumab in salivary glands and explore relationships with clinical assessments

Detailed description

This is an open-label, non-randomized, biopsy-based mechanistic study on pharmacokinetics, pharmacodynamics, safety and tolerability of ianalumab in patients with Sjögren's syndrome.

Conditions

Interventions

TypeNameDescription
BIOLOGICALIanalumabIanalumab VAY736 150mg/1ml Solution for injection

Timeline

Start date
2022-07-27
Primary completion
2024-06-26
Completion
2026-01-05
First posted
2021-11-18
Last updated
2026-02-02

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT05124925. Inclusion in this directory is not an endorsement.