| Recruiting | CLEAR-AS: CT-FFR-Guided Revascularization in Patients With Severe Aortic Stenosis NCT07469371 | Yan'an Affiliated Hospital of Kunming Medical University | N/A |
| Not Yet Recruiting | Application of TAVI at Experienced Interventional Cardiac Centers Without On-site Cardiac Surgery (ATLAS Study NCT06818006 | University of Alberta | Phase 4 |
| Recruiting | Safety and Efficacy of the RENATUS® Transcatheter Aortic Valve System for the Treatment of Severe Aortic Steno NCT07414342 | Beijing Balance Medical Technology Co., Ltd | N/A |
| Recruiting | Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR NCT07309029 | Atlantic Health System | — |
| Recruiting | Navitor Japan Study NCT07193888 | Abbott Medical Devices | — |
| Recruiting | A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System NCT07194265 | Anteris Technologies Ltd. | N/A |
| Recruiting | Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI) NCT06898086 | Rede Optimus Hospitalar SA | N/A |
| Completed | Alwide Plus China Post-market Clinical Investigation NCT07304427 | Shanghai MicroPort CardioFlow Medtech Co., Ltd. | — |
| Recruiting | Act on Quality of Life in Patients With aortIc Stenosis NCT06477042 | Hospices Civils de Lyon | — |
| Enrolling By Invitation | Observational Study Relating to the Long-term Follow-up of Patients with Severe Aortic Stenosis Evaluated for NCT06679517 | University Hospital of Ferrara | — |
| Unknown | VARC-TAVI VALVE IMPLANTATION) NCT06177392 | Hospital Universitario La Paz | N/A |
| Recruiting | Comparison of a Single Versus Double Perclose Technique for TAVR NCT06173115 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Effica NCT06136429 | Pan Xiangbin | N/A |
| Unknown | Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR NCT06015997 | Jordan Collaborating Cardiology Group | — |
| Completed | Prevalence of Cusp Asymmetry, Coronary Ostial Eccentricity in Patients Undergoing Trans Catheter Aortic Valve NCT06834828 | Ain Shams University | — |
| Recruiting | Aspirin vs Clopidogrel After TAVR NCT05493657 | Yonsei University | N/A |
| Completed | SAvvyWire™ EFficacy and SafEty in Transcatheter Aortic Valve Implantation Procedures (SAFE-TAVI) NCT05492383 | Opsens, Inc. | N/A |
| Recruiting | Safety and Performance Study of the Optimum Transcatheter Aortic Valve NCT04076150 | Thubrikar Aortic Valve, Inc. | N/A |
| Recruiting | Colibri Transcatheter Aortic Heart Valve System Study NCT04029844 | Colibri Heart Valve LLC | N/A |
| Completed | Intravenous Iron Supplement for Iron Deficiency in Patients With Severe Aortic Stenosis NCT04206228 | Oslo University Hospital | Phase 2 |
| Completed | Improved HRV, Inflammation Markers and Endothelial Function After TAVI NCT04286893 | University Medical Centre Ljubljana | — |
| Unknown | Evaluate the Transcatheter Artificial Aortic Valve and Transcatheter Artificial Heart Values Delivery System NCT03788590 | Ningbo Jenscare Biotechnology Co., Ltd. | N/A |
| Completed | CONFIDENCE Registry to Assess Safety and Performance of Portico System to Treat Patients With Severe Aortic St NCT03752866 | Abbott Medical Devices | N/A |
| Terminated | Safety and Efficacy of SYM-SV/DS-002 in Patients With Severe Aortic Stenosis NCT03004599 | Medico's Hirata Inc. | N/A |
| Unknown | Primary Non-invasive Cardiac Computed Tomography Versus Routine Invasive Angiography Prior to TAVI NCT03291925 | BC Centre for Improved Cardiovascular Health | N/A |
| Unknown | Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study NCT03280433 | Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. | — |
| Withdrawn | HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON CANADA NCT02159794 | HLT Inc. | N/A |
| Completed | HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON NCT02157142 | HLT Inc. | N/A |
| Completed | Open-label, Randomized Trial in Participants Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs NCT01651780 | The Medicines Company | Phase 3 |
| Completed | Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis Wit NCT01675440 | Medtronic Cardiovascular | — |
| Completed | Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease NCT02575768 | Samsung Medical Center | — |
| Active Not Recruiting | Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic St NCT01586910 | Medtronic Cardiovascular | N/A |
| Completed | Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic NCT01531374 | Medtronic Cardiovascular | N/A |
| Completed | Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Ste NCT01240902 | Medtronic Cardiovascular | N/A |
| Completed | SOURCE XT REGISTRY NCT01238497 | Edwards Lifesciences | — |
| Completed | CoreValve Advance International Post Market Study NCT01074658 | Medtronic Cardiac Rhythm and Heart Failure | — |
| Completed | Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressin in Valve-Replacement NCT01994330 | Pontificia Universidad Catolica de Chile | Phase 4 |