Trials / Completed
CompletedNCT02575768
Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease
Reduced Myocardial Flow Reserve in Exertional Angina With Severe Aortic Stenosis and Normal Coronary Arteries: Insight From Prospective Observational Adenosine-stress Cardiac Magnetic Resonance Imaging Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 104 (actual)
- Sponsor
- Samsung Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Exertional angina is common symptom in patients with severe aortic stenosis (AS) without obstructive coronary artery disease (CAD). Although reduced myocardial flow reserve is one of the proposed explanations for angina, little is known about the pathophysiology. This study aimed that adenosine-stress cardiac magnetic resonance can be used for the assessment of myocardial perfusion reserve and suggest the pathophysiology of development of angina in patients with severe AS without obstructive CAD.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Adenosine-stress cardiac magnetic resonance imaging | undergoing adenosine-stress cardiac magnetic resonance imaging |
Timeline
- Start date
- 2012-06-01
- Primary completion
- 2015-04-01
- Completion
- 2015-04-01
- First posted
- 2015-10-15
- Last updated
- 2015-10-15
Source: ClinicalTrials.gov record NCT02575768. Inclusion in this directory is not an endorsement.