| Not Yet Recruiting | Steroid Treatment for Severe Acute Respiratory Infection (STAR) Trial NCT07199192 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 4 |
| Suspended | Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19 NCT04386070 | University of Birmingham | Phase 3 |
| Withdrawn | A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Comp NCT04838847 | CureVac | Phase 3 |
| Terminated | COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV NCT04860258 | CureVac | Phase 3 |
| Completed | Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT) NCT04636671 | University of Trieste | Phase 3 |
| Completed | Communication in ICU During COVID-19 NCT04602351 | NMC Specialty Hospital | — |
| Completed | Safety and Tolerability of COVID-19 Vaccine (ABNCoV2) NCT04839146 | Radboud University Medical Center | Phase 1 |
| Completed | A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19 NCT04674189 | CureVac | Phase 3 |
| Terminated | Ivermectin in Adults With Severe COVID-19. NCT04602507 | CES University | Phase 2 |
| Completed | COVID-19 Health Professional Impact Study NCT04527432 | The Royal Wolverhampton Hospitals NHS Trust | N/A |
| Completed | LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID- NCT04402957 | Arch Biopartners Inc. | Phase 2 |
| Completed | COVID-19-Related Health and Practices Among Dental Hygienists NCT04542915 | American Dental Association | — |
| Completed | A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healt NCT04515147 | CureVac | Phase 2 |
| Unknown | Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-8 NCT04480333 | Biomed Industries, Inc. | Phase 1 |
| Completed | Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19 NCT04470544 | Alan Bryce | Phase 2 |
| Completed | COVID-19 Seroprevalence Study in French Guiana NCT04490850 | Institut Pasteur | N/A |
| Completed | A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Respons NCT04444700 | University of Sao Paulo General Hospital | Phase 3 |
| Completed | Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tübingen Children NCT04581889 | University Hospital Tuebingen | — |
| Unknown | Northeast COVID-19 and Pregnancy Study Group NCT04462367 | Instituto Materno Infantil Prof. Fernando Figueira | — |
| Terminated | Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2 NCT04320511 | Corewell Health East | — |
| Unknown | Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 NCT04433949 | Emory University | Phase 3 |
| Unknown | Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration NCT04627623 | Medical University of Silesia | — |
| Completed | A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVI NCT04449276 | CureVac | Phase 1 |
| Completed | Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease NCT04376684 | GlaxoSmithKline | Phase 2 |
| Completed | A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 NCT04402060 | Apellis Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Completed | COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss NCT04395144 | Hôpital de Verdun | N/A |
| Completed | Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection NCT04357730 | Denver Health and Hospital Authority | Phase 2 |
| Completed | Obesity and Mortality of Critically Ill Patients With COVID-19 NCT04425213 | Central Hospital, Nancy, France | — |
| Completed | Study of the Pathogenesis of Olfactory Disorders in COVID-19 NCT04366934 | Institut Pasteur | — |
| Completed | Ivermectin, Aspirin, Dexamethasone and Enoxaparin as Treatment of Covid 19 NCT04425863 | Eurnekian Public Hospital | — |
| Completed | Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19 NCT04745442 | Maimónides Biomedical Research Institute of Córdoba | Phase 2 |
| Completed | Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial NCT04324463 | Population Health Research Institute | Phase 3 |
| Terminated | Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVI NCT04335786 | Radboud University Medical Center | Phase 4 |
| Completed | Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial) NCT04315896 | National Institute of Respiratory Diseases, Mexico | Phase 3 |
| Completed | Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial) NCT04318015 | National Institute of Respiratory Diseases, Mexico | Phase 3 |
| Withdrawn | Intermediate IND Severe Illness COVID-19 CP NCT04411602 | Henry Ford Health System | Phase 1 |
| Unknown | Covid-19 and Diabetes in West of Algeria NCT04412746 | Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen | — |
| Completed | Household Transmission Investigation Study for COVID-19 in Tropical Regions NCT04328129 | Institut Pasteur | N/A |
| Recruiting | Randomised Evaluation of COVID-19 Therapy NCT04381936 | University of Oxford | Phase 3 |
| Completed | Effect of Early Implementation of Prone Positioning NCT06287554 | Zulekha Hospitals | — |
| Unknown | Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19 NCT04381819 | Oslo University Hospital | — |
| Completed | Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure NCT03225807 | Intermountain Health Care, Inc. | — |
| Completed | Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS NCT03465085 | Beni-Suef University | Phase 3 |
| Completed | Collection of Convalescent SARS Plasma by Apheresis NCT00342524 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | Contamination During Removal of Two Different Personal Protective Systems NCT00150475 | Queen's University | N/A |
| Completed | Study of Alferon® LDO (Low Dose Oral) in Normal Volunteers NCT00215826 | AIM ImmunoTech Inc. | Phase 2 |
| Withdrawn | Evaluation and Treatment of Severe Acute Respiratory Syndrome (SARS) NCT00073086 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Withdrawn | The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes NCT00172263 | National Taiwan University Hospital | N/A |
| Unknown | A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / NCT00578825 | Hospital Authority, Hong Kong | N/A |