| Recruiting | SGLT2 Inhibitors in Geographic Atrophy NCT07174687 | Washington University School of Medicine | Phase 2 |
| Recruiting | 4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800 NCT07024719 | Duke University | N/A |
| Not Yet Recruiting | An Interpretable Fundus Diseases Report Generating System Based On Weakly Labelings NCT06918028 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Enrolling By Invitation | Evaluation of Retinal Parameters in Patients With Epiretinal Membrane After Vitrectomy NCT07165626 | Pomeranian Medical University Szczecin | N/A |
| Active Not Recruiting | Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study NCT06162585 | Nanoscope Therapeutics Inc. | — |
| Completed | Clinical Investigation of a New Version of MAIA Microperimeter on Healthy Subjects and Patients With Retinal P NCT06071546 | Centervue SpA | N/A |
| Completed | Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DM NCT06011798 | Unity Biotechnology, Inc. | Phase 2 |
| Recruiting | Real-world of AI in Diagnosing Retinal Diseases NCT05981950 | Beijing Tongren Hospital | — |
| Active Not Recruiting | Recurrence and Predictive OCT Biomarkers in Quiescent Neovascular AMD NCT06717139 | St. Erik Eye Hospital | — |
| Recruiting | Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical App NCT05724641 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Completed | Evaluation of Diabetic Retinopathy Using Ultra-Widefield Fundus Images Compared With Two-Field Fundus Images NCT05836194 | Ningbo Eye Hospital | — |
| Unknown | Pistachios and Neural Macular Pigment NCT05283941 | Tufts University | N/A |
| Unknown | Evaluating the Safety of the SPECTRALIS CENTAURUS Device NCT04968756 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Long-shaft Vitrectomy Probe in Highly Myopic Eyes NCT04902170 | National Taiwan University Hospital | N/A |
| Completed | Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] NCT04945772 | Nanoscope Therapeutics Inc. | Phase 2 |
| Unknown | AI Classifies Multi-Retinal Diseases NCT04592068 | Beijing Tongren Hospital | — |
| Unknown | Artificial Intelligence System for Assessing Image Quality of Fundus Images and Its Effects on Diagnosis NCT04289064 | Sun Yat-sen University | — |
| Completed | Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravitreal vMCO-I in Patients With Advanced NCT04919473 | Nanoscope Therapeutics Inc. | Phase 1 / Phase 2 |
| Completed | Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD NCT03954626 | Novartis Pharmaceuticals | Phase 3 |
| Completed | Artificial Intelligence for Detecting Retinal Diseases NCT04678375 | Beijing Tongren Hospital | — |
| Completed | Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated NCT02946879 | MeiraGTx UK II Ltd | — |
| Completed | Advanced OCT and Adaptive Optics Imaging in Retinal Disease (The ACAD Study) NCT02828215 | Moorfields Eye Hospital NHS Foundation Trust | — |
| Completed | Efficacy of Ranibizumab Therapy With Aflibercept in Patients With Diabetic Macular Edema NCT02646670 | Instituto de Olhos de Goiania | Phase 4 |
| Completed | Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Pat NCT02543229 | Opthea Limited | Phase 1 |
| Completed | Long-Working Distance OCT for Children NCT02582164 | Duke University | N/A |
| Terminated | X-82 to Treat Age-related Macular Degeneration NCT02348359 | Tyrogenex | Phase 2 |
| Completed | Clinical Evaluation of the RAVI-Guide NCT02196584 | Medical College of Wisconsin | — |
| Recruiting | DISCOVER Study: Microscope-integrated Intraoperative OCT Study NCT02423213 | The Cleveland Clinic | — |
| Completed | Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration NCT02157077 | Centre Hospitalier Intercommunal Creteil | Phase 3 |
| Unknown | An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovasc NCT01521065 | Oraya Therapeutics, Inc. | Phase 2 |
| Completed | Measuring Corneal Cells With Specular Microscopy NCT01792154 | Retina Institute of Hawaii | — |
| Completed | Microcurrent Stimulation to Treat Macular Degeneration NCT01790958 | Retina Institute of Hawaii | — |
| Terminated | GW824575 First Time in Human NCT01551771 | GlaxoSmithKline | Phase 1 |
| Completed | Intravitreal Ranibizumab Combined With Panretinal Photocoagulation in Patients With Proliferative Diabetic Ret NCT01746563 | University of Sao Paulo | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa NCT01399515 | Seoul National University Hospital | Phase 2 |
| Completed | Spectral Domain Optical Coherence Tomography Imaging of the Eyes of Neonates NCT01404247 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 1 |
| Terminated | Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2) NCT01225146 | David M. Brown, M.D. | Phase 1 |
| Completed | High-Dose Lucentis (Ranibizumab 2.0mg) for the Treatment of Nonproliferative Idiopathic Parafoveal Telangiecta NCT01205035 | Eye Center of Northern Colorado, P.C. | Phase 2 |
| Completed | INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD NCT01016873 | Oraya Therapeutics, Inc. | Phase 2 |
| Unknown | Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Seconda NCT01217762 | Oraya Therapeutics, Inc. | Phase 1 |
| Active Not Recruiting | Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations NCT00481546 | University of Pennsylvania | Phase 1 |
| Completed | Genetic Study of Patients Suffering From Congenital Amaurosis of Leber or From an Early Severe Retinal Dystrop NCT00422721 | Nantes University Hospital | N/A |
| Completed | UHR-OCT and HD-OCT for Preretinal Membranes: ICG Versus Membrane Blue NCT00437593 | The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery | N/A |
| Completed | Effect of Levodopa on Human Multifocal Electroretinogram NCT00812760 | Medical University of Vienna | Phase 4 |
| Completed | Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pa NCT00001668 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Central Vein Occlusion Study (CVOS) NCT00000131 | National Eye Institute (NEI) | Phase 3 |