Trials / Completed
CompletedNCT01792154
Measuring Corneal Cells With Specular Microscopy
Specular Photomicrograpic Assessment of the Effect of Anti-VEGF Intravitreal Injections on Corneal Thickness and Endothelial Cell Density and Morphology
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (actual)
- Sponsor
- Retina Institute of Hawaii · Academic / Other
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Accepted
Summary
Assess changes in the corneal cell count using Specular Microscopy following tretments with Anti-VEGF injections
Detailed description
Patients with active Wet AMD often receive intraocular Anti-VEGF injections such as Macugen, Lucentis and Avastin on a monthly basis for an extended period of time. While these medications are very effective at controlling the Choroidal Neovascularization associated with this disease, the impact of monthly intravigtreal Anti-VEGF injections on the viability of corneal endothelial cells has yet to be fully characterized. The availability of CESM as a diagnostic test that can be performed quickly and painlessly in the clinic offers a method of tracking corneal endothelial cell count in this patient population.
Conditions
Timeline
- Start date
- 2012-08-01
- Primary completion
- 2012-11-01
- Completion
- 2012-11-01
- First posted
- 2013-02-15
- Last updated
- 2013-02-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01792154. Inclusion in this directory is not an endorsement.