| Recruiting | Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for NCT07405476 | Emory University | Phase 2 |
| Recruiting | Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer NCT07407647 | Ohio State University Comprehensive Cancer Center | Phase 2 |
| Not Yet Recruiting | Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma NCT07363863 | Sohag University | — |
| Recruiting | A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in R NCT06424522 | Ohio State University Comprehensive Cancer Center | N/A |
| Recruiting | Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays NCT07283939 | Alliance for Clinical Trials in Oncology | N/A |
| Recruiting | PET-imaging of Two Vartumabs in Patients With Solid Tumors NCT06645808 | Var2 Pharmaceuticals | EARLY_Phase 1 |
| Recruiting | Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer NCT06965166 | Mayo Clinic | — |
| Active Not Recruiting | A Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophy NCT06662643 | Zhongnan Hospital | N/A |
| Unknown | Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma NCT05685680 | Sohag University | N/A |
| Recruiting | Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma NCT04749108 | Institut du Cancer de Montpellier - Val d'Aurelle | Phase 2 / Phase 3 |
| Completed | Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced NCT04505553 | University of Washington | Phase 2 |
| Unknown | Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253 NCT04848311 | Nanfang Hospital, Southern Medical University | N/A |
| Active Not Recruiting | Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiatio NCT04713618 | Ohio State University Comprehensive Cancer Center | — |
| Completed | Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survi NCT04205955 | SWOG Cancer Research Network | Phase 2 |
| Unknown | PR in Endoscopic LAR for Rectal Cancer NCT04078828 | Southwest Hospital, China | N/A |
| Terminated | Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Lo NCT04066894 | M.D. Anderson Cancer Center | Phase 2 |
| Unknown | COLOR III Trial: Transanal vs Laparoscopic TME NCT02736942 | Amsterdam UMC, location VUmc | Phase 3 |
| Terminated | Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay NCT02797405 | Centre Leon Berard | N/A |
| Unknown | Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer NCT02817126 | Fudan University | N/A |
| Active Not Recruiting | Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy NCT02432963 | City of Hope Medical Center | Phase 1 |
| Unknown | Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer NCT02770911 | Fujian Medical University | Phase 3 |
| Completed | Neoadjuvant Treatment for Advanced Rectal Carcinoma NCT02551237 | UNICANCER | Phase 3 |
| Active Not Recruiting | Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymph NCT02465060 | National Cancer Institute (NCI) | Phase 2 |
| Unknown | IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment NCT02268006 | Institute of Oncology Ljubljana | Phase 2 |
| Unknown | Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum NCT01899547 | Fujian Medical University | N/A |
| Completed | Phase II Study of Up-front Chemotherapy and Neo-adjuvant Short-course Radiotherapy for Resectable Rectal Carci NCT02000050 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | Phase 2 |
| Completed | PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study NCT01751516 | UNC Lineberger Comprehensive Cancer Center | — |
| Completed | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcar NCT01372007 | University Hospital, Ghent | Phase 3 |
| Completed | Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma NCT01333709 | Institut du Cancer de Montpellier - Val d'Aurelle | Phase 2 |
| Terminated | Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia NCT01111292 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Unknown | Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting NCT01227239 | Japan Clinical Cancer Research Organization | Phase 1 / Phase 2 |
| Unknown | Resource-Sparing Curative Treatment for Rectal Cancer NCT01459328 | International Atomic Energy Agency | Phase 3 |
| Completed | Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma NCT00682786 | Washington University School of Medicine | Phase 2 |
| Active Not Recruiting | Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial) NCT01696981 | National Cancer Institute (NCI) | N/A |