| Recruiting | Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor NCT07336173 | Kafrelsheikh University | — |
| Not Yet Recruiting | The Combined Effect of Magnesium, Palmitoylethanolamide, High-Molecular-weight Hyaluronic Acid, Vitamin B6, an NCT07305519 | University of Roma La Sapienza | N/A |
| Recruiting | The Combined First Trimester Screening NCT07015203 | Institute of Health Information and Statistics of the Czech Republic | — |
| Enrolling By Invitation | Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Qualit NCT06687044 | Jun Wei | N/A |
| Recruiting | PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients) NCT07263490 | Copenhagen University Hospital, Hvidovre | — |
| Not Yet Recruiting | Effects of Kangaroo Care on Circadian Rhythm, Growth and Physiological Effects NCT06589349 | Sibel Küçükoğlu | N/A |
| Withdrawn | Calcium Aspirin Multiple Micronutrients (CAMMS) to Reduce Preterm Birth NCT05612984 | Johns Hopkins Bloomberg School of Public Health | Phase 3 |
| Unknown | Cervical Volume and Prediction of Preterm Labor NCT06190496 | Assiut University | — |
| Completed | The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Pr NCT06168149 | Ankara Etlik City Hospital | — |
| Unknown | Cyclin-dependent Kinase Inhibitor 2A (Placental Senescence Marker) on Labor-related Signals NCT05864066 | Assiut University | — |
| Unknown | Adjunctive Vaginal Progesterone in Management of Preterm Labor NCT05997563 | Chulalongkorn University | Phase 4 |
| Unknown | Effect Of Azithromycin in Women at Risk of Preterm Labour NCT05971654 | Beni-Suef University | Phase 2 / Phase 3 |
| Recruiting | Development and Clinical Evaluation of an Innovative Medical Device to Predict Preterm Birth (PrediMAP) NCT05586334 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Fetal Brain Growth - Pilot Study NCT05994443 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Unknown | Labor Status Monitor for Diagnosing True vs False Labor in Preterm Patients NCT06157203 | PreTeL, Inc | — |
| Completed | HUMAN CHORIONIC GONADOTROPIN (HcG) VS MAGNESIUM SULPHATE (MgSo4) AS A TOCOLYTIC AGENT- A RANDOMIZED CONTROLLED NCT05828966 | Shaheed Zulfiqar Ali Bhutto Medical University | N/A |
| Completed | Baby Smell Visual Stimulus Program Cortical and Breast Oxygenation Milk Amount Mother-Infant Attachment NCT06058208 | Selcuk University | N/A |
| Completed | Amniochorionic Membrane Cells in the Maternal Blood as a Biomarker for Preterm Birth NCT04705935 | University of Aarhus | — |
| Terminated | Bryophyllum Pinnatum Treatment of Anxiety Related to Signs of Preterm Birth NCT05110599 | Christian Haslinger | Phase 2 |
| Active Not Recruiting | Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnanc NCT06053697 | University of Liverpool | — |
| Unknown | Aspiration Technique-based Device for Preterm Labor NCT05355649 | Federico II University | N/A |
| Recruiting | Low Dose Antenatal Corticosteroids for Late Preterm Delivery NCT05698966 | Rambam Health Care Campus | N/A |
| Completed | Uterocervical Angle in Prediction of Preterm Labor NCT05632003 | Ain Shams Maternity Hospital | — |
| Active Not Recruiting | MIRACLE of LIFE Study NCT06074601 | Mirvie | — |
| Completed | To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis NCT04831086 | Fundacion Clinic per a la Recerca Biomédica | Phase 3 |
| Recruiting | Maternal Stress on Human Milk and Infant Outcomes NCT04821544 | University of Idaho | N/A |
| Completed | The Association Between Parathyroid Hormone and Preterm Labor NCT05688007 | Ain Shams Maternity Hospital | — |
| Completed | Impact of Suspected Preterm Labour on Cardiometabolic Profile and Neurodevelopment NCT05211297 | Instituto de Investigación Sanitaria Aragón | — |
| Completed | The Cervical Length and Thickness of Cesarean Section Scar With Preterm Labor NCT04554745 | Assiut University | N/A |
| Terminated | Ibuprofen Versus Indomethacin Following Emergent Cerclage Placement NCT04726085 | Woman's | N/A |
| Unknown | The Efficacy of Nifedipine in the Management of Preterm Labor NCT04644354 | Ethem Unal, M.D., PhD, Associate Prof of Surgery & Surgic | — |
| Unknown | Uterocervical Angle and Preterm Labour NCT04532086 | Ain Shams Maternity Hospital | — |
| Active Not Recruiting | Omega-3 Fatty Acids for Smoking Cessation in Pregnancy NCT04417595 | Vanderbilt University Medical Center | Phase 2 |
| Active Not Recruiting | Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs NCT04301518 | Sera Prognostics, Inc. | N/A |
| Completed | Lockdown Impact on Spontaneous Premature Birth in a Level III NICU NCT04605172 | Central Hospital, Nancy, France | — |
| Unknown | Prediction of the Onset of Term and Preterm Labour NCT04590677 | Chelsea and Westminster NHS Foundation Trust | — |
| Withdrawn | Indomethacin for Tocolysis of Preterm Labor NCT01869361 | MetroHealth Medical Center | EARLY_Phase 1 |
| Unknown | Transabdominal Cervical Length Predict Preterm Labor During Routine Antenatal Screening NCT04313673 | Karadeniz Technical University | — |
| Completed | Analyze Changes in Respiratory Rate When Using the Scare Respirator NCT04584814 | Pontificia Universidad Catolica de Chile | N/A |
| Completed | The Effect of Facilitated Tucking After Vaginal Delivery on Late Preterm Stress, Comfort and Physiological Par NCT05430321 | Istanbul University - Cerrahpasa | N/A |
| Unknown | The FLIP-1 Study: Vaginal Lactobacillus Supplementation in Women at High Risk of Preterm Birth NCT03992534 | Imperial College London | Phase 1 |
| Recruiting | Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA NCT04047849 | Woman's | Phase 4 |
| Completed | Oral Dydrogesterone in the Management of Preterm Labor NCT03935152 | Chulalongkorn University | Phase 4 |
| Unknown | Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening NCT03837288 | Ain Shams University | N/A |
| Completed | Uterocervical Angle in Patients With Preterm Premature Rupture of the Membranes NCT04095507 | Nefise Nazlı YENIGUL | N/A |
| Completed | Uterocervical Angle in Idiopathic Polyhydramnios NCT03828695 | Nefise Nazlı YENIGUL | N/A |
| Completed | Vaginal Progesterone for the Prolongation of Pregnancy After Arrested Pre-term Labor NCT02430233 | HaEmek Medical Center, Israel | Phase 4 |
| Completed | Multichannel EMG Diagnosing True Preterm Labor NCT03785795 | PreTeL, Inc | — |
| Unknown | Correlation Between Maternal Vitamin D Level And Preterm Birth NCT03638037 | Ain Shams Maternity Hospital | — |
| Completed | Diagnostic Tests in the Context of Threatened Preterm Labour NCT03608995 | University Hospital, Clermont-Ferrand | N/A |
| Unknown | UTEROCERVİCAL ANGLE MEASUREMENT IN SPONTANEOUS PRETERM BIRTH (UAMSPB) NCT03623685 | Istanbul Medeniyet University | N/A |
| Completed | Biomarkers in Obstetrical Complications NCT03480139 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Completed | Interest of a Vaginal Swab in Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth NCT03401255 | Nantes University Hospital | — |
| Unknown | Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor NCT03610841 | Recep Tayyip Erdogan University Training and Research Hospital | — |
| Unknown | PoC Study of OBE022 in Threatened Preterm Labour NCT03369262 | ObsEva SA | Phase 2 |
| Unknown | Study on Prevention, Treatment and Mechanism of Preterm Labor for Chinese Pregnant Women ≥35 Years Old NCT03210415 | Ministry of Science and Technology of the People´s Republic of China | — |
| Completed | Oral Versus Parental Progesterone in the Management of Preterm Labor NCT03343795 | Assiut University | Phase 4 |
| Unknown | Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour. NCT03205020 | mona nematallah | — |
| Completed | Vaginal Progesterone Supplementation in the Management of Preterm Labor NCT03202836 | Chulalongkorn University | N/A |
| Completed | Group Antenatal/Postnatal Care in Rwanda NCT03154177 | University of California, San Francisco | N/A |
| Unknown | Extended-spectrum β-lactamase -Producing Enterobacteriaceae (ESBL) Vertical Transmission in Women With Preterm NCT03251885 | Western Galilee Hospital-Nahariya | — |
| Unknown | The Impact of Cervical Cerclage or Vaginal Progesterone on Vaginal Microbiome Distribution NCT03253016 | Western Galilee Hospital-Nahariya | N/A |
| Completed | Ultrasonographic Evaluation of Fetal Adrenal Gland in Cases of Threatened Preterm Labor NCT03251794 | Assiut University | — |
| Suspended | Electrical Inhibition of Human Preterm Contractions NCT02983240 | e-Bio Corp | N/A |
| Unknown | Magnesium Effect on Embryonal PR Interval NCT03047304 | Rambam Health Care Campus | N/A |
| Completed | This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary NCT04296591 | Karadeniz Technical University | — |
| Completed | Progestrone and Doppler Indices NCT03292939 | Kasr El Aini Hospital | Phase 2 / Phase 3 |
| Completed | Strengthening Facility-based Intrapartum/Immediate Newborn Care to Reduce Mortality of Preterm Infants in Migo NCT03112018 | University of California, San Francisco | N/A |
| Unknown | Different Types of Progesterone in the Prevention of Preterm Labor NCT03537287 | Ain Shams University | Phase 2 |
| Completed | Intramuscular Hydroxyprogesterone Caproate and Placenta Previa NCT03130504 | Assiut University | Phase 2 |
| Unknown | Use of Pessary in Case of Cervical Insufficiency and Short Cervix NCT03096691 | Zeynep Kamil Maternity and Pediatric Research and Training Hospital | N/A |
| Completed | Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow NCT02591004 | Kasr El Aini Hospital | Phase 2 / Phase 3 |
| Withdrawn | Effectiveness of ACS in Extreme Preemies NCT02351310 | Pediatrix | Phase 3 |
| Completed | Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Bei NCT02536352 | Johns Hopkins University | EARLY_Phase 1 |
| Withdrawn | Group B Streptococcus (GBS) Infection and in Preterm Labor Women Conceived Through IVF NCT03122704 | Manh Tuong Ho | N/A |
| Completed | Efficacy and Safety of MgSO4 as Tocolytics Compared to Ritodrine in Preterm Labor NCT02538718 | Seoul National University Hospital | N/A |
| Completed | Comparison Between Natural Progesterone and Vaginal Pessary for the Prevention of Spontaneous Preterm Birth NCT02511574 | University of Sao Paulo | Phase 4 |
| Completed | Maternal Serum Homocysteine Levels and Uterine Artery Pulsatility Indices in Preterm Labor NCT03440281 | Benha University | — |
| Completed | Prediction of Preterm Labor in Asymptomatic High Risk Women NCT03334877 | Zagazig University | — |
| Terminated | Nifedipine or Nifedipine Plus Indomethacin for Treatment of Acute Preterm Labor NCT02438371 | The University of Texas Health Science Center, Houston | Phase 4 |
| Terminated | A Phase 2 Study of OBE001 Versus Placebo in the Delay of Preterm Birth NCT02326142 | ObsEva SA | Phase 2 |
| Completed | Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor NCT03171675 | Ain Shams University | — |
| Completed | Impact of the PREEMI Package on Neonatal Mortality NCT03923023 | University of Alabama at Birmingham | — |
| Completed | Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor NCT02262481 | Chulalongkorn University | N/A |
| Unknown | Nanovectors to Prevent Placental Passage of Tocolytic Agents NCT02199756 | The University of Texas Health Science Center, Houston | — |
| Completed | Nifedipine for Acute Tocolysis of Preterm Labor NCT02132533 | University of Texas Southwestern Medical Center | Phase 3 |
| Unknown | Nifedipine Pharmacokinetics and Pharmacodynamics When Used as a Tocolytic in Acute Threatened Preterm Labour NCT02068404 | Chantal Csajka | Phase 4 |
| Unknown | Utrogestan Versus Nifedipine as Tocolysis for Preterm Labor: a Randomised Controlled Trial NCT01985594 | nor zila hassan malek | Phase 2 |
| Completed | Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery NCT02521688 | Ain Shams University | — |
| Unknown | Preterm Labor Prediction by Cervical Contour in Ultrasound NCT01912508 | Meir Medical Center | — |
| Recruiting | Prospective Data Bank Creation to Study Vaginal Conditions NCT01829204 | Texas Tech University Health Sciences Center | — |
| Completed | Development of Pharmacokinetics Model in Pregnancy Women and Fetus NCT01916330 | Seoul National University Hospital | — |
| Completed | Biomarkers Associated With Spontaneous Preterm Birth Less Than 32 Wks Gestation NCT02317315 | Ranjith Kamity, MD | — |
| Completed | Screening To Obviate Preterm Birth NCT01868308 | University of Pennsylvania | — |
| Unknown | Pilot Study Testing a New Strategy for Management of Spontaneous Preterm Birth NCT02108886 | Université de Sherbrooke | Phase 2 |
| Unknown | Role of Serum Total Antioxidant Level in Preterm Labor NCT01518816 | Ain Shams Maternity Hospital | — |
| Completed | Two Methods of Diagnosing Preterm Labor NCT01431885 | University of California, San Francisco | N/A |
| Withdrawn | Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor NCT01406197 | St. Joseph's Hospital and Medical Center, Phoenix | N/A |
| Completed | Individualized Dosing of Nifedipine For Tocolysis in Preterm Labor NCT02090920 | Indiana University | — |
| Unknown | Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy NCT01281319 | Promyco Diagnostics | — |
| Completed | The Effect of Antenatal Corticosteroids on the Fetal Thymus - a Possible Role in Fetal Immune Programming NCT03057717 | Unity Health Toronto | N/A |
| Completed | Phospholipase A2 Producing Bacteria and Pre-Term Labor NCT00855543 | CAMC Health System | — |
| Completed | The Biomarker Study NCT01148654 | University of Pennsylvania | — |
| Terminated | Extended Release Nifedipine Treatment as Maintenance Tocolysis to Prevent Preterm Delivery NCT00525486 | The Baruch Padeh Medical Center, Poriya | N/A |
| Terminated | Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women NCT03715530 | Mark Santillan | N/A |
| Completed | Tocolysis for Preterm Labor NCT00811057 | University of Mississippi Medical Center | N/A |
| Completed | Establishment of a Perinatal Database and a Bank of Biological Materials NCT00339235 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |