NCT07336173

Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor

Role of Uterine Artery Doppler Indices and Sonographic Measurement of Uterocervical Angle in Predicting Preterm Labor

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 47 (estimated)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to evaluate the role of uterine artery doppler indices and uterocervical angle measurement in prediction of preterm labor .The main question it aims to answer is: Does combination of both uterine artery doppler indices and uterocervical angle measurement increase sensitivity and specificity for prediction of established preterm labor ? Participants already performing uterine artery doppler as part of their regular antenatal care .measurement of anterior uterocervical angle will be added between 24 to 34 weeks gestation to predict preterm labor in candidates .

Detailed description

In this study the aim is to evaluate the combined predictive value of both uterine artery doppler and uterocervical angle measurement in a prospective cohort study design to predict preterm labor . The abnormal mid-trimester uterine artery resistance, pulsatility index and diastolic notching measured with Doppler sonography is known to be predictive for preeclampsia and, hence, for iatrogenic Preterm labor. It will be measured via trans abdominal approach. The measurement of UCA in the second trimester of pregnancy is strongly associated with the occurrence of spontaneous Preterm labor and will be measured via transvaginal approach . Both measurement will be conducted between 24 to 34 weeks gestational .

Conditions

• Preterm Labor

Interventions

Type	Name	Description
DEVICE	Ultrasound	Trans abdominal ultrasound will be used to measure uterine artery doppler indices Trans vaginal ultrasound will be used to measure anterior uterocervical angle

Timeline

• Start date: 2026-01-15
• Primary completion: 2026-04-01
• Completion: 2026-06-01
• First posted: 2026-01-13
• Last updated: 2026-01-20

Locations

1 site across 1 country: Egypt