| Enrolling By Invitation | Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVAR NCT07511660 | Healing Hope International | — |
| Unknown | Autologous ADMSC Transplantation in Patients With POI NCT06132542 | Mongolian National University of Medical Sciences | Phase 1 |
| Completed | The Impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency NCT06117982 | Trio Fertility | Phase 2 |
| Recruiting | Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therap NCT05890417 | University Hospital, Bordeaux | N/A |
| Unknown | The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age NCT05838157 | Sun Yat-sen University | — |
| Unknown | A Multicenter Open-label Clinical Study on the Prevention of Premature Ovarian Failure After HSCT NCT05667428 | First Affiliated Hospital Xi'an Jiaotong University | N/A |
| Unknown | Intra-ovarian Injection of MSC-EVs in Idiopathic Premature Ovarian Failure NCT06202547 | Royan Institute | Phase 1 / Phase 2 |
| Recruiting | The Danish TURNER Cryopreservation Study NCT05740579 | University of Aarhus | N/A |
| Unknown | Brain MRI Imaging Changes and Associated Factors on Cognition Function in Patients With Premature Ovarian Fail NCT06121388 | International Peace Maternity and Child Health Hospital | — |
| Unknown | A Clinical Study of Chinese Herbal Compound TJAOA101 in the Treatment of Premature Ovarian Insufficiency NCT05522634 | Tongji Hospital | EARLY_Phase 1 |
| Active Not Recruiting | Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment. NCT05462379 | MARILIA ALBANEZI BERTOLAZZI | Phase 1 / Phase 2 |
| Active Not Recruiting | The Use of Expandeded Mesenchymal Stromal Cells (MSC) in Premature Ovarian Failure (POF) in Adult Humans NCT04815213 | University of Jordan | Phase 1 |
| Unknown | Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency NCT04922398 | Ahmed Saad | Phase 1 / Phase 2 |
| Recruiting | Is There A Role For Mechanical Stimulation In Ovarian Follicular Activation? NCT04390308 | ART Fertility Clinics LLC | — |
| Active Not Recruiting | Will Autologous Platelet Rich Plasma Able To Restore Ovarian Function? NCT04381299 | ART Fertility Clinics LLC | — |
| Unknown | Levels of Selected Macroelements in Premature Ovarian Insufficiency NCT04800705 | Cengiz Gokcek Women's and Children's Hospital | — |
| Unknown | Levels of Selected Microelements in Premature Ovarian Insufficiency NCT04767451 | Cengiz Gokcek Women's and Children's Hospital | — |
| Completed | Long Term Follow up Patients With Premature Ovarian Failure ex Vivo Gene Therapy NCT04675970 | Ukraine Association of Biobank | — |
| Completed | A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Failure NCT02912104 | International Peace Maternity and Child Health Hospital | Phase 1 |
| Unknown | Ovarian Fragmentation Study (Crespo Medical Team) NCT04306185 | Equipo Juana Crespo | N/A |
| Unknown | Turner Syndrome Minipuberty Study NCT04189406 | Radboud University Medical Center | — |
| Completed | Effects of Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response and Premature Ovarian Insuffi NCT04237909 | Acibadem University | N/A |
| Completed | Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency NCT04149028 | Tanta University | N/A |
| Recruiting | Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients NCT04031456 | Genesis Athens Clinic | Phase 2 / Phase 3 |
| Withdrawn | Very Small Embryonic-like Stem Cells for Ovary NCT03985462 | Fuda Cancer Hospital, Guangzhou | Phase 1 / Phase 2 |
| Unknown | Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation NCT04009473 | Forever Young d.o.o. | Phase 1 / Phase 2 |
| Unknown | Prevention of Chemotherapy-Induced Ovarian Failure With Goserelin in Premenopausal Lymphoma Patients NCT04536467 | Beni-Suef University | Phase 2 |
| Completed | Effects of UCA-PSCs in Women With POF NCT05138367 | Li-jun Ding | Phase 1 |
| Suspended | The Safety and Efficiency Study of Mesenchymal Stem Cell (19#iSCLife®-POI) in Premature Ovarian Insufficiency NCT03816852 | Sclnow Biotechnology Co., Ltd. | Phase 2 |
| Completed | Endocan Levels in Women With Premature Ovarian Insufficiency NCT03924648 | Cengiz Gokcek Women's and Children's Hospital | — |
| Unknown | Prospective Genetic Study in Patients With Ovarian Insufficiency NCT03474120 | The First Affiliated Hospital of Anhui Medical University | — |
| Completed | Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infer NCT04071574 | Lebanese University | Phase 1 / Phase 2 |
| Active Not Recruiting | Preservation of Ovarian Cortex Tissue in Girls With Turner Syndrome NCT03381300 | Radboud University Medical Center | N/A |
| Unknown | Ovarian Histopathology and Laparoscopic Assessment of Premature Ovarian Failure NCT03412487 | Cairo University | N/A |
| Unknown | Human Amniotic Epithelial Cells Treatment for Ovarian Insufficiency NCT03207412 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Unknown | Second Step Protocol in Poor Ovarian Responder (POR) NCT03480412 | Università degli Studi 'G. d'Annunzio' Chieti e Pescara | — |
| Completed | Inovium Ovarian Rejuvenation Trials NCT03178695 | Ascendance Biomedical | Phase 1 |
| Unknown | Single Follicular Dexarelix for LH Suppression During Ovarian Stimulation in Oocyte Donors. NCT03861715 | Assisting Nature | — |
| Completed | Filgrastim for Premature Ovarian Insufficiency NCT02783937 | South Valley University | Phase 4 |
| Terminated | Autologous Bone Marrow Transplantation for Premature Ovarian Insufficiency NCT02779374 | South Valley University | N/A |
| Completed | Rejuvenation of Premature Ovarian Failure With Stem Cells NCT02696889 | University of Illinois at Chicago | N/A |
| Completed | Transplantation of HUC-MSCs With Injectable Collagen Scaffold for POF NCT02644447 | Chinese Academy of Sciences | Phase 1 / Phase 2 |
| Unknown | Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure ( NCT02603744 | Royan Institute | Phase 1 / Phase 2 |
| Unknown | Autologous Bone Marrow-Derived Stem Cell Transplantation in Patients With Premature Ovarian Failure (POF) NCT03069209 | Stem Cells Arabia | Phase 1 / Phase 2 |
| Unknown | Autologous Stem Cells Transplantation in Patients With Idiopathic and Drug Induced Premature Ovarian Failure NCT02043743 | El-Rayadh Fertility Centre | Phase 1 / Phase 2 |
| Unknown | Effects of ADSC Therapy in Women With POF NCT01853501 | Nanjing University | Phase 4 |
| Unknown | Stem Cell Therapy Combined Hormone Replacement Therapy in Patients With Premature Ovarian Failure NCT01742533 | Shenzhen Beike Bio-Technology Co., Ltd. | Phase 1 / Phase 2 |
| Completed | "It is a Real" The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure NCT02372474 | Al-Azhar University | Phase 1 / Phase 2 |
| Unknown | Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure NCT02062931 | Sayed Bakry | Phase 1 / Phase 2 |
| Completed | Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure NCT02151890 | Al-Azhar University | Phase 1 / Phase 2 |
| Completed | Blood Spot Self-administered Test and Assay NCT03840824 | University of Pennsylvania | — |
| Terminated | The Natural History of Reproductive and Overall Health in Girls and Women With a Pre-Mutation in the FMR1 Gene NCT01187524 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Withdrawn | The Use of DHEA in Women With Premature Ovarian Failure NCT01129947 | Virginia Center for Reproductive Medicine | EARLY_Phase 1 |
| Terminated | Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF) NCT00948857 | David H. Barad | Phase 2 / Phase 3 |
| Active Not Recruiting | Ovarian Reserve After Cancer: Longitudinal Effects NCT02467231 | University of Pennsylvania | — |
| Completed | Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism NCT00837616 | Nemours Children's Clinic | Phase 4 |
| Unknown | Inactive FSH in Galactosemia NCT00619333 | Maastricht University Medical Center | N/A |
| Completed | Modified Natural Cycle Offers a Chance of Pregnancy in Patients With Poor Response and High Basal FSH NCT00417157 | Eugonia | — |
| Withdrawn | Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure NCT00370019 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 |
| Completed | X-Chromosome Inactivation Status and Premature Ovarian Failure NCT00295087 | University of Pittsburgh | — |
| Unknown | 'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologis NCT00119925 | Radboud University Medical Center | N/A |
| Unknown | Premature Ovarian Failure (Genetic and Physiopathologic Analysis) NCT00780897 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders NCT00417066 | Eugonia | Phase 4 |
| Completed | GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients NCT00429494 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failur NCT00732693 | University of Edinburgh | Phase 4 |
| Completed | Estrogen Treatment (Oral vs. Patches) in Turner Syndrome NCT00140998 | Nemours Children's Clinic | Phase 3 |
| Completed | Feasibility Study for Development of an Early Test for Ovarian Failure NCT00006156 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | N/A |
| Completed | Hormone Replacement in Young Women With Premature Ovarian Failure NCT00001951 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 |
| Completed | Steroid Therapy in Autoimmune Premature Ovarian Failure NCT00001306 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Completed | Ovarian Follicle Function in Patients With Primary Ovarian Failure NCT00001275 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |