NCT03985462

Very Small Embryonic-like Stem Cells for Ovary

Autologous Very Small Embryonic-like Stem Cells(VSELs) for Premature Ovarian Failure

• Status: Withdrawn
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Fuda Cancer Hospital, Guangzhou · Academic / Other
• Sex: Female
• Age: 30 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is the safety and efficacy of autologous very small embryonic-like stem cells(VSELs) to premature ovarian failure.

Detailed description

Premature ovarian failure is diagnosed by blood femal hormones test of follicle stimulating hormone (FSH, \> 40 IU/L)、luteinizing hormon (LH, \> 40 IU/L)、estradiol (E2, \> 100pg/mL) and/or amenorrhea before the age of 40. VSELs come from the patient's periperal blood, and will be injected in bilateral oviducts, followed-up by hormone testing and menstrual conditions.

Conditions

• Stem Cell Transplant Complications
• Premature Ovarian Failure

Interventions

Type	Name	Description
BIOLOGICAL	very small embryonic-like stem cell	Mononuclear cells were collected from peripheral blood of each patient using a machine, VSELs were isolated, and each group was injected according to different numbers after activation

Timeline

• Start date: 2019-07-03
• Primary completion: 2020-05-30
• Completion: 2020-06-30
• First posted: 2019-06-13
• Last updated: 2020-10-19

Locations

1 site across 1 country: China