| Not Yet Recruiting | Male Pelvic Floor Muscle Rehabilitation Exercises NCT07451808 | Dream Video LLC | N/A |
| Recruiting | The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation NCT07442396 | Uskudar University | N/A |
| Not Yet Recruiting | Vagus Nerve Stimulation in Premature Ejaculation NCT07300774 | Bahçeşehir University | N/A |
| Not Yet Recruiting | Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Ra NCT07236632 | Benha University | N/A |
| Recruiting | Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Rep NCT07434271 | Kadence Bio | Phase 2 |
| Not Yet Recruiting | Comparison of the Efficacy and Safety of Dapoxetine, Kegel Exercises, and Acupuncture in the Treatment of Prem NCT07067970 | Medipol University | N/A |
| Not Yet Recruiting | Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination NCT07057011 | South Valley University | N/A |
| Recruiting | Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial NCT06570135 | Xijing Hospital | N/A |
| Completed | THE IMPACT OF VITAMIN B12 TREATMENT ON EJACULATORY FUNCTIONS IN MEN: SYMPTOMATIC RELIEF AND IMPROVED OUTCOMES NCT07036497 | OZGUR EKICI | — |
| Not Yet Recruiting | Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men NCT06571318 | Herbolab India Pvt. Ltd. | N/A |
| Active Not Recruiting | Safety and Efficacy of Botulinum Toxin-A Injection Into Ischiocavernosus Muscle for Premature Ejaculation NCT06851598 | Abdallah Mohamed Abdallah Mohamed Elgendy | Phase 2 / Phase 3 |
| Not Yet Recruiting | Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature Ejaculation NCT05052879 | EMS | Phase 3 |
| Recruiting | Ejaculatory and Orgasmic Dysfunction Registry NCT06605469 | Charitable Union for the Research and Education of Peyronie's Disease | — |
| Recruiting | Development and Validation of an Anxiety Disorder Prediction Model for Premature Ejaculation Patients NCT06677814 | Xijing Hospital | — |
| Unknown | The Study on the Effectiveness and Safety of Electroacupuncture at ST36 in Treating Primary Premature Ejaculat NCT06172855 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | N/A |
| Unknown | The Safety of Dapoxetine/Tadalafil Combination Therapy NCT03177746 | Neutec Ar-Ge San ve Tic A.Ş | Phase 4 |
| Unknown | Sildenafil Added Effect in Dapoxetine Non-responding Mono-symptomatic Premature Ejaculation (PE) NCT05556083 | Al-Azhar University | Phase 2 |
| Completed | A Comparative Study of Selective Dorsal Neurectomy, Pulsed Radiofrequency Neuromodulation, and Intragranular H NCT06777199 | Ahmed Hamdy Ahmed | N/A |
| Completed | The Prevalence of Erectile Dysfunction (ED) and Premature Ejaculation (PE) in Poland NCT05462171 | Jagiellonian University | — |
| Recruiting | Effectiveness and Safety of TENS Therapy for Premature Ejaculation NCT06425224 | Boston Medical Group | Phase 3 |
| Unknown | Precise Use of Lidocaine Cream to Treat Primary Premature Ejaculation NCT05749614 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Effect of Respiratory Exercises On The Intravaginal Ejaculation Latency Time NCT05517694 | Bahçeşehir University | N/A |
| Completed | Transcutaneous Electrical Nerve Stimulation for the Treatment of Premature Ejaculation NCT06570512 | Cairo University | N/A |
| Unknown | Combined On-demand Sildenafil Citrate and Tramadol Hydrochloride for Treatment of Premature Ejaculation NCT05183334 | Assiut University | Phase 4 |
| Recruiting | Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation. NCT06425211 | Boston Medical Group | N/A |
| Completed | The Effect of Behavioral Therapy Given to Men and Their Partners' NCT05964608 | University of Gaziantep | N/A |
| Unknown | Erectile Dysfunction, Psychological Disorders, and Sexual Performance Among Men Seeking Medical Help for Ferti NCT04941690 | The First Hospital of Jilin University | — |
| Completed | Brain Networks Implicated in Lifelong Premature Ejaculation Patients NCT04850703 | Moises Domingo | Phase 1 / Phase 2 |
| Recruiting | Transcutaneous Posterior Tibial Nerve Stimulation for Premature Ejaculation NCT04207723 | Boston Medical Group | N/A |
| Unknown | Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile Dysfunctio NCT04361305 | Yan-Ping Huang | Phase 3 |
| Unknown | Effectiveness and Tolerability of the On-demand Use of Combined Dapoxetine With Tadalafil and Combined Dapoxet NCT04703127 | Sohag University | Phase 3 |
| Completed | Evaluation of the Safety and Effectiveness of the vPatch Device NCT03942367 | Virility Medical Ltd. | N/A |
| Unknown | A Multicenter Case-control Study of Risk Factors for Premature Ejaculation in China's Shaanxi Province NCT04235192 | Xijing Hospital | — |
| Completed | Efficacy of App and Electronic Device in the Treatment of Premature Ejaculation NCT04012437 | Instituto Sexológico Murciano | N/A |
| Completed | Chronotype and Premature Ejaculation NCT04841395 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Unknown | Effect of Tamsulosin on PE Compared With Paroxetine Hydrochloride NCT03879746 | Assiut University | Phase 3 |
| Completed | Evaluation of the Clinical Efficacy and Safety of Dapoxetine, Combined Dapoxetine With Folic Acid and Combined NCT04085354 | Sohag University | Phase 3 |
| Completed | PSD502 in Subjects With Premature Ejaculation NCT03578783 | Plethora Solutions Ltd | Phase 2 |
| Unknown | Investigation of the Changes of Brain Structure and Function in Premature Ejaculation Patients and the Effects NCT03583112 | Xidian University | N/A |
| Completed | Efficacy of a New Behavioral Treatment for Premature Ejaculation Using a Masturbation Aid Device: Star-Stop 3. NCT03304808 | Instituto Sexológico Murciano | N/A |
| Completed | TPTNS for Treating Patients With Premature Ejaculation NCT03204890 | Boston Medical Group | N/A |
| Completed | IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT), Patient Reported Outcomes and Safety in Men With NCT03055806 | Ixchelsis Limited | Phase 2 |
| Unknown | Effects of Proxelan Somministration in Patients With Chronic Prostatitis NCT03629769 | University of Pisa | Phase 3 |
| Unknown | Safety & Feasibility of Functional Electrical Stimulation for The Treatment of Premature Ejaculation NCT03177226 | Virility Medical Ltd. | N/A |
| Unknown | Discontinuation of Dapoxetine Treatment in Patients With Premature Ejaculation NCT03018743 | Pusan National University Hospital | — |
| Completed | Safety Demonstration of Increasing Intensities of Electrical Stimulation Delivered to The Bulbospongiosus Musc NCT03174470 | Virility Medical Ltd. | N/A |
| Completed | Effect of Exercise on Premature Ejaculation NCT02984592 | Ankara Training and Research Hospital | — |
| Completed | The Efficacy and Safety of Dapoxetine/Sildenafil Combination Therapy NCT02939495 | Neutec Ar-Ge San ve Tic A.Ş | Phase 4 |
| Completed | Glans Penis Augmentation by Hyaluronic Acid for Treatment of Premature Ejaculation NCT03459833 | Cairo University | Phase 3 |
| Completed | A Study to Evaluate Efficacy of Investigational Product HeezOn Ultra -1/ HeezOn Ultra-2 on Male Sexual Health NCT02794454 | Vedic Lifesciences Pvt. Ltd. | N/A |
| Terminated | Consultations Reason for Genital, Urinary or Psychological Humans in General Practice NCT02378779 | University Hospital, Brest | N/A |
| Unknown | A Phase 2 Study of On-demand Therapy With Clomipramine and Sildenafil Combination in Premature Ejaculation NCT02571101 | CTC Bio, Inc. | Phase 2 |
| Completed | Research and Clinical Value of New Classification for Premature Ejaculation: Multi-Center Research NCT02572037 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | The Impact and Benefit of Physical Activity on Premature Ejaculation NCT02844998 | Ankara Training and Research Hospital | N/A |
| Completed | IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT) and Patient Reported Outcomes in Men With Prematu NCT02232425 | Ixchelsis Limited | Phase 2 |
| Completed | A New Treatment for Premature Ejaculation? NCT02297152 | Instituto Sexológico Murciano | N/A |
| Completed | Primary Premature Ejaculation Genetics NCT02109302 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Unknown | Efficacy of Promescent Lidocaine Spray in Men With Premature Ejaculation NCT02241460 | Eugene Y Rhee, MD | Phase 3 |
| Unknown | Safety and Efficacy of Silodosin in the Treatment of Premature Ejaculation NCT02581826 | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | Phase 2 |
| Terminated | A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation NCT01917006 | Allergan | Phase 2 |
| Unknown | Male Reproductive Health of Floating Population: a Large-Scale Survey in Dongguan NCT01901029 | First Affiliated Hospital, Sun Yat-Sen University | — |
| Unknown | Management of Sexual Dysfunction With Bioresonance Technique NCT02028013 | Man Clinic for Andrology, Male Infertility and Sexual Dysfunction | — |
| Unknown | Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation NCT01798667 | Dong-A Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Trial of PED-1 in Male Patients With Premature Ejaculation NCT01439984 | Symyoo | Phase 3 |
| Completed | Safety, Tolerability, Pharmacokinetics and Efficacy of YHD1044 NCT01419470 | Yuhan Corporation | Phase 1 / Phase 2 |
| Completed | Phase 2 Trial of PED-1 and PED-2 in Male Patients With Premature Ejaculation NCT01203202 | Symyoo | Phase 2 |
| Completed | A Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment of Premature Ejaculation NCT01184105 | Plethora Solutions Ltd | Phase 1 |
| Completed | A Study To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Oral Doses of GSK55 NCT01021553 | GlaxoSmithKline | Phase 2 |
| Completed | A Safety and Tolerability Study of Administration of PSD502 NCT01183208 | Plethora Solutions Ltd | Phase 1 |
| Terminated | Study to Evaluate Efficacy and Safety in Male Subjects With Premature Ejaculation NCT00983736 | Bausch Health Americas, Inc. | Phase 3 |
| Terminated | Study to Evaluate Efficacy and Safety in Males Subjects With Premature Ejaculation NCT00983151 | Bausch Health Americas, Inc. | Phase 3 |
| Completed | Proof of Mechanism in ELT NCT00861484 | GlaxoSmithKline | Phase 1 |
| Completed | Efficacy and Safety of Paroxetine Daily Doses of 15 mg and 20 mg in the Treatment of Premature Ejaculation NCT01024491 | MorePharma Corporation | Phase 3 |
| Unknown | Safety and Efficacy of Escitalopram in the Treatment of Premature Ejaculation NCT00656552 | Cairo University | EARLY_Phase 1 |
| Completed | FTIH Study With GSK958108 NCT00664365 | GlaxoSmithKline | Phase 1 |
| Completed | Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation NCT00556478 | Plethora Solutions Ltd | Phase 2 / Phase 3 |
| Completed | A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296. NCT00549211 | GlaxoSmithKline | Phase 1 |
| Terminated | A Study To Assess The Pharmacokinetics Of Different Modified Release Formulations Of GSK221149 In Healthy Adul NCT00449709 | GlaxoSmithKline | Phase 1 |
| Completed | A Study On Concentrations Of 16448 In Blood And The Safety Of This Compound In Healthy Males With Premature Ej NCT00537459 | GlaxoSmithKline | Phase 2 |
| Completed | Exploratory Study of Pagoclone in Men With Premature Ejaculation. NCT00370981 | Endo Pharmaceuticals | Phase 2 |