NCT04703127

Effectiveness and Tolerability of the On-demand Use of Combined Dapoxetine With Tadalafil and Combined Dapoxetine With Lidocaine 5% Spray in Treatment of Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Alone.

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: Male
• Age: 20 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Therefore, this study will aim to assess the effectiveness and tolerability of the on-demand use of combined dapoxetine with tadalafil and combined dapoxetine with lidocaine 5% spray in treatment of patients with lifelong premature ejaculation and non-responding to dapoxetine alone.

Detailed description

This study will be carried out on 60 patients with lifelong premature ejaculation and non-responding to dapoxetine alone. All patients will be equally divided into 2 groups (30 patients each). Group 1 was given on-demand 30 mg dapoxetine and 10 mg tadalafil 1 h before intercourse. Group 1 was given on-demand 30 mg dapoxetine 1 h before intercourse and apply lidocaine 5% spray on the glans penis 10 minutes the wash before intercourse.

Conditions

• Premature Ejaculation

Interventions

Type	Name	Description
DRUG	Tadalafil and Combined Dapoxietine	Group 1 was given on-demand 30 mg dapoxetine and 10 mg tadalafil 1 h before intercourse.
DRUG	Dapoxietine and Combined Lidocaine 5% Spray	Group 2 was given on-demand 30 mg dapoxetine 1 h before intercourse and apply lidocaine 5% spray on the glans penis 10 minutes the wash before intercourse.

Timeline

• Start date: 2020-03-30
• Primary completion: 2021-01-30
• Completion: 2021-01-30
• First posted: 2021-01-11
• Last updated: 2021-01-11

Locations

1 site across 1 country: Egypt