| Not Yet Recruiting | Low Dose Naltrexone Use in Patients With POTS NCT05363514 | University of Calgary | Phase 4 |
| Recruiting | NC Testing in LC & POTS NCT05914649 | University of Calgary | N/A |
| Recruiting | CAlgary SAlt for POTS NCT05924646 | University of Calgary | N/A |
| Recruiting | Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS) NCT06292104 | University of Texas Southwestern Medical Center | — |
| Completed | Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS NCT06268288 | Mayo Clinic | N/A |
| Completed | Using Mirabegron to Increase BP in Patients With POTS NCT06133075 | Cedars-Sinai Medical Center | Phase 2 |
| Recruiting | The Long COVID-19 Wearable Device Study NCT05741112 | Scripps Translational Science Institute | N/A |
| Completed | A Shared Medical Appointment Intervention for Quality of Life Improvement in POTS NCT05454137 | University of Arizona | N/A |
| Unknown | Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort NCT05481177 | Uniformed Services University of the Health Sciences | Phase 4 |
| Enrolling By Invitation | Effects of Individual Tailored Physical Exercise in Patients With POTS After COVID-19 - a Randomized Controlle NCT05877534 | Karolinska Institutet | N/A |
| Recruiting | Postural Sway and Counterpressure Maneuvers for Pediatric Syncope NCT05633693 | Simon Fraser University | N/A |
| Unknown | Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hy NCT05923840 | New York Medical College | N/A |
| Completed | Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS NCT05633407 | argenx | Phase 2 |
| Recruiting | Paediatric Syncope in the Emergency Department NCT05555771 | Dr. Victoria Claydon | N/A |
| Completed | Breathing Exercises With And Without Aerobic Training In Patients With Postural Orthostatic Tachycardia Syndro NCT05404672 | Riphah International University | N/A |
| Active Not Recruiting | Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome NCT05344599 | Vanderbilt University Medical Center | — |
| Active Not Recruiting | Physical Training in Patients With POTS After Covid-19 NCT05094622 | Karolinska Institutet | N/A |
| Withdrawn | A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS NCT03365414 | University of Alberta | Phase 3 |
| Completed | POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS NCT06054958 | Technical University of Munich | — |
| Recruiting | Compression Garments in the Community With POTS NCT04881318 | University of Calgary | N/A |
| Recruiting | Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome NCT05212129 | Medical College of Wisconsin | N/A |
| Withdrawn | Iron Sucrose in Patients With Iron Deficiency and POTS NCT04855266 | Mayo Clinic | Phase 2 |
| Completed | The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue NCT03674541 | Brigham and Women's Hospital | Phase 2 |
| Completed | Remote Self-training Program for Patients With Postural Orthostatic Tachycardia Syndrome NCT04603157 | Mayo Clinic | N/A |
| Completed | Vagus Nerve Stimulation in Treatment of Postural Orthostatic Tachycardia Syndrome NCT03930914 | University of Oklahoma | N/A |
| Completed | CRI in POTS in Adolescents NCT03974737 | University of Colorado, Denver | — |
| Completed | Effect of Ivabradine on Patients With Postural Orthostatic Tachycardia Syndrome NCT03182725 | University of California, San Diego | Phase 3 |
| Completed | Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAU NCT04875949 | Istituto Clinico Humanitas | N/A |
| Enrolling By Invitation | Autoimmune Basis for Postural Tachycardia Syndrome NCT02725060 | Vanderbilt University Medical Center | N/A |
| Terminated | Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS) NCT01978535 | Mayo Clinic | Phase 1 / Phase 2 |
| Active Not Recruiting | Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome NCT02196376 | Vanderbilt University | — |
| Completed | Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) NCT02171988 | Seoul National University Hospital | Phase 4 |
| Completed | Gabapentin Treatment of Postural Tachycardia Syndrome (PoTS) NCT04345432 | Medstar Health Research Institute | N/A |
| Active Not Recruiting | Transdermal Vagal Stimulation for POTS NCT02281097 | Vanderbilt University | N/A |
| Terminated | High Sodium Diet and External Abdominal Compression in POTS NCT01771484 | Vanderbilt University | Phase 1 |
| Completed | Dietary Salt in Postural Tachycardia Syndrome NCT01547117 | Vanderbilt University | N/A |
| Completed | Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrom NCT01563107 | Vanderbilt University Medical Center | N/A |
| Completed | Tilt Table With Suspected Postural Orthostatic Tachycardia Syndrome (POTS) Subjects NCT01617616 | Wake Forest University Health Sciences | — |
| Terminated | Hemodynamic Response of Neuropathic And Non-Neuropathic POTS Patients To Adrenoreceptor Agonist And Antagonist NCT03070730 | Beth Israel Deaconess Medical Center | Phase 1 / Phase 2 |
| Completed | Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life NCT01367977 | Genetic Disease Investigators | — |
| Active Not Recruiting | Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS) NCT00962728 | Alfredo Gamboa | N/A |
| Unknown | Cardiovascular Effects of Selective I(f)-Channel Blockade NCT00865917 | Hannover Medical School | Phase 2 |
| Completed | Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS),P NCT00728026 | Medical College of Wisconsin | — |
| Active Not Recruiting | Pathophysiology of Orthostatic Intolerance NCT00608725 | Satish R. Raj | N/A |