| Not Yet Recruiting | Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery NCT07354698 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Phase 4 |
| Recruiting | Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid NCT07140757 | M.D. Anderson Cancer Center | — |
| Recruiting | A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer. NCT06791005 | Second Affiliated Hospital of Xi'an Jiaotong University | Phase 3 |
| Recruiting | Ultrasound-guided Thermal Ablation for Papillary Thyroid Carcinoma NCT06733740 | Chinese PLA General Hospital | — |
| Recruiting | A Study of Online Follow-up in Patients With Papillary Thyroid Cancer NCT06800482 | West China Hospital | N/A |
| Recruiting | Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples NCT06133374 | University of Calgary | — |
| Recruiting | The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma NCT06316895 | Chinese PLA General Hospital | — |
| Completed | Molecular Analysis for Precision Surgery in Thyroid Cancer Trial NCT06235814 | University of California, Los Angeles | N/A |
| Recruiting | Prediction of Lymph Node Metastasis in Patients With Thyroid Malignancy by a New Scale NCT06286631 | Second Affiliated Hospital of Xi'an Jiaotong University | — |
| Recruiting | Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of Patients NCT06468696 | Second Affiliated Hospital of Xi'an Jiaotong University | N/A |
| Recruiting | Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC NCT05668962 | Massachusetts General Hospital | Phase 2 |
| Terminated | Oral AMXT 1501 Dicaprate in Combination With IV DFMO NCT05500508 | Aminex Therapeutics, Inc. | Phase 1 / Phase 2 |
| Completed | Radiofrequency Ablation of Papillary Thyroid Microcarcinoma NCT05132205 | Johns Hopkins University | N/A |
| Completed | Oxidative Stress and Mitochondrial TERT in Papillary Thyroid Cancer. NCT05752669 | Istituto Auxologico Italiano | — |
| Active Not Recruiting | Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid NCT04948437 | National Taiwan University Hospital | — |
| Recruiting | Targeted Therapy to Increase RAI Uptake in Metastatic DTC NCT05024929 | Children's Hospital of Philadelphia | — |
| Unknown | A Clinical Study of Transaxillary Endoscopic and Open Thyroidectomy for PTC NCT05545852 | Nanfang Hospital, Southern Medical University | N/A |
| Completed | A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors NCT04731467 | Famewave Ltd. | Phase 1 / Phase 2 |
| Active Not Recruiting | Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer NCT04624477 | University Health Network, Toronto | — |
| Unknown | Percentage of BRAFV600E Alleles and Outcome in Thyroid Carcinoma NCT04664413 | University of Salerno | — |
| Active Not Recruiting | PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer NCT04544111 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Unknown | The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma NCT04076514 | Assiut University | — |
| Completed | Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation NCT04129411 | Mayo Clinic | N/A |
| Completed | Papillary Thyroid Cancer and Central Lymp Node Dissection NCT05873283 | Başakşehir Çam & Sakura City Hospital | — |
| Unknown | Treatment Efficacy and Safety of Low-dose Radioiodine Ablation for Intermediate-risk Differentiated Thyroid Ca NCT04354324 | Zhujiang Hospital | N/A |
| Active Not Recruiting | A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nerv NCT03899792 | Eli Lilly and Company | Phase 1 / Phase 2 |
| Recruiting | Definition of Mutational Profile of Papillary Thyroid Tumors by Mass-ARRAY NCT05766098 | Istituto Auxologico Italiano | — |
| Terminated | A Study to Try to Bring Back Radioiodine Sensitivity in Patients With Advanced Thyroid Cancer. NCT03469011 | AHS Cancer Control Alberta | Phase 1 |
| Terminated | Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer NCT03630120 | H. Lee Moffitt Cancer Center and Research Institute | Phase 2 |
| Completed | Precision Thyroid Cancer Surgery With Molecular Fluorescent Guided Imaging NCT03470259 | University Medical Center Groningen | Phase 1 |
| Unknown | Evaluation of Accuracy of One-Step Nucleic Acid Amplification (OSNA) in Diagnosis of Lymph Node Metastases of NCT03889769 | University of Cagliari | — |
| Active Not Recruiting | Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (T NCT02568267 | Hoffmann-La Roche | Phase 2 |
| Completed | Clinical Validation of a Predictive Model for the Presence of Cervical Lymph Node Metastasis in Papillary Thyr NCT02442661 | University of Colorado, Denver | — |
| Completed | More Than 50% of Unifocal cN0 T1b/Small T2 Papillary Thyroid Carcinoma May Require Completion Thyroidectomy if NCT06439745 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Predictive MRI Metrics for Tumor Aggressiveness in Papillary Thyroid Cancer NCT02178345 | Memorial Sloan Kettering Cancer Center | — |
| Unknown | Comparative Analysis Between Bipolar Device and Conventional Tie & Suture Technique in Thyroidectomy NCT02140476 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | N/A |
| Terminated | Percutaneous Ethanol Injection for Primary Papillary Thyroid Microcarcinoma NCT01974284 | Yale University | N/A |
| Completed | Image-guided Thermal Ablation vs. Lobectomy for Solitary Papillary Thyroid Microcarcinoma NCT06325787 | Chinese PLA General Hospital | N/A |
| Completed | Dabrafenib With or Without Trametinib in Treating Patients With Advanced Differentiated Thyroid Cancer NCT01723202 | Bhavana Konda | Phase 2 |
| Completed | Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liv NCT01502410 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer Treatment NCT01441154 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | CT Detection of Metastatic Lymphadenopathy in Papillary Thyroid Cancer NCT03359668 | University Health Network, Toronto | N/A |
| Completed | A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid T NCT01100619 | Exelixis | Phase 1 |
| Unknown | Pilot 99mTechnetium-MIBI Single Photon Emission Computed Tomography - Computed Tomography (SPECT-CT) in Papill NCT00984191 | Chulalongkorn University | N/A |
| Completed | Sutent Adjunctive Treatment of Differentiated Thyroid Cancer NCT00668811 | Medstar Health Research Institute | Phase 2 |
| Completed | Study of XL281 in Adults With Solid Tumors NCT00451880 | Exelixis | Phase 1 |
| Completed | The Incidence of Postoperative Re-stratification for Recurrence in Well-differentiated Thyroid Cancer - A Sing NCT04500925 | Tel-Aviv Sourasky Medical Center | — |
| Completed | Prophylactic Central Neck Dissection for Papillary Thyroid Cancer NCT01510002 | Jagiellonian University | N/A |
| Recruiting | Studies on Tumors of the Thyroid NCT00001160 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Overdiagnosis of Thyroid Cancer in the Marne and Ardennes Departments of France From 1975 to 2014 NCT03623516 | CHU de Reims | — |
| Approved For Marketing | Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation NCT03906331 | Eli Lilly and Company | — |