NCT01510002

Prophylactic Central Neck Dissection for Papillary Thyroid Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 640 (actual)
• Sponsor: Jagiellonian University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether prophylactic central neck dissection is beneficial for patients with papillary thyroid cancer staged preoperatively as node negative.

Detailed description

Several respected organizations have recently recommended that total thyroidectomy plus prophylactic central neck dissection should be the standard operation for papillary thyroid cancer. However, it is still unclear if this approach has any benefit on survival or locoregional control of the disease. In addition, potential advantages of this more aggressive surgical approach should outweigh the risk of morbidity. The purpose of this retrospective cohort study is to determine whether prophylactic central neck dissection is beneficial for patients with papillary thyroid cancer staged preoperatively as node negative. In this study outcomes of total thyroidectomy versus this plus prophylactic central neck dissection for papillary thyroid cancer are compared in a 10-year follow-up. Patients operated between 1993 and 1997 (n=282) underwent total thyroidectomy alone, whereas patients operated between 1998 and 2002 (n=358) underwent total thyroidectomy plus prophylactic central neck dissection.

Conditions

• Papillary Thyroid Cancer

Interventions

Type	Name	Description
PROCEDURE	Total thyroidectomy	Extracapsular total thyroidectomy
PROCEDURE	Total thyroidectomy + prophylactic central neck dissection	Extracapsular total thyroidectomy plus prophylactic central neck dissection

Timeline

• Start date: 1993-01-01
• Primary completion: 2011-09-01
• Completion: 2011-12-01
• First posted: 2012-01-13
• Last updated: 2012-01-13

Locations

1 site across 1 country: Poland