| Enrolling By Invitation | Automated Manual Lymphatic Drainage Therapy to Improve Glymphatic Function in OSA Patients NCT07301762 | Mayo Clinic | N/A |
| Recruiting | Impact of Muscle Training Device on Non-Severe OSA NCT06910930 | Thammasat University Hospital | N/A |
| Recruiting | The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease NCT07060079 | University College, London | — |
| Recruiting | Diagnosing Obstructive Sleep Apnea Using Electromyography of the Muscles of the Mouth NCT06944782 | University of California, San Diego | — |
| Active Not Recruiting | A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight NCT06649045 | Eli Lilly and Company | Phase 3 |
| Recruiting | Inspire Singapore Study NCT06540716 | Inspire Medical Systems, Inc. | N/A |
| Recruiting | Detecting Heart Rate, Respiration, and Sleep With the Sleeptracker-AI Under-mattress Monitor NCT06110962 | Woolcock Institute of Medical Research | — |
| Recruiting | Lifestyle Changes in PCOS with OSA and NAFLD NCT06591169 | Cairo University | N/A |
| Enrolling By Invitation | Continuation Protocol for Obstructive Sleep Apnea (OSA) NCT06566820 | Apnimed | Phase 3 |
| Completed | Study That Tests AD109 in Patients Taking GLP-1 Drugs NCT06400615 | Apnimed | Phase 2 |
| Recruiting | Reversible Effect of Falling Ventilatory Drive in Drive-dependent OSA NCT06091098 | Brigham and Women's Hospital | N/A |
| Active Not Recruiting | Prevalence of OSA and Diagnostic Accuracy of Type 3 Home Sleep Test in Difficult-to-treat Asthma NCT06916858 | Chulalongkorn University | N/A |
| Recruiting | Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA NCT06091085 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Completed | Hypoxic Burden and Sleepiness in Treated OSA Patients NCT06700837 | Hospices Civils de Lyon | — |
| Completed | Mandibular Advancement Device and Changes in Nocturia NCT05562388 | Fernanda Yanez Regonesi | N/A |
| Unknown | Biomarkers of Dementia in Chronic Sleep and Breathing Disorders NCT06377332 | Woolcock Institute of Medical Research | — |
| Completed | Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea NCT05944965 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Completed | Prospective Study for the Clinical Validation of the Soundi Wearable Medical Device NCT06320795 | Biocubica srl | N/A |
| Unknown | Prevalence of OSA in Patients of ILD NCT06058052 | Assiut University | — |
| Recruiting | Impact of Patient Involvement in Alerts Management of Telemonitoring CPAP NCT05960175 | Asten Sante | N/A |
| Completed | Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study) NCT05813275 | Apnimed | Phase 3 |
| Completed | Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo) NCT05811247 | Apnimed | Phase 3 |
| Unknown | Assessment of Knowledge and Attitude Toward Obstructive Sleep Apnea in Medical Teams NCT05990777 | Assiut University | — |
| Suspended | Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients NCT03647891 | Kaiser Permanente | N/A |
| Completed | Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome NCT05857475 | Mahidol University | N/A |
| Completed | AD816 Crossover Study NCT05793684 | Apnimed | Phase 2 |
| Completed | Ultrasonographic of Diaphragmatic Function in Obstructive Sleep Apnea NCT07370376 | Mansoura University | — |
| Completed | Using an Educational Video to Enhance Adherence of CPAP Therapy in Thai OSA Patients: a Randomised Controlled NCT06684717 | Siriraj Hospital | N/A |
| Completed | Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold NCT05763329 | Chulalongkorn University | Phase 1 / Phase 2 |
| Unknown | Impact of Intermittent Hypoxia on Neutrophil Extracellular Traps NCT05485688 | Taipei Veterans General Hospital, Taiwan | — |
| Completed | Predictability of OSA With a Subjective Screening Scale (OSASSS1) NCT06092710 | Center for Sleep Medicine - Clinique André Renard | — |
| Completed | Attitudes Toward Obstructive Sleep Apnea-Related Cause of Road Traffic Accidents in Thailand Through Well Prep NCT05734742 | Chulalongkorn University | N/A |
| Completed | Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea NCT05881512 | Somnial Inc | N/A |
| Enrolling By Invitation | Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring NCT05462600 | University of California, San Diego | — |
| Recruiting | Long-term Benefits of CPAP or MAD Treatment on the Sleep of OSAS Patients NCT05435794 | ResMed | — |
| Completed | STOP-Bang Score and Factors Predicting Difficult Intubation for Prediction of Difficult Mask Ventilation in Ob NCT06265064 | Khon Kaen University | — |
| Recruiting | Obstructive Sleep Apnea (OSA), Oral Frailty, Dysphagia, Continuous Positive Airway Pressure (CPAP) NCT05977296 | National Cheng-Kung University Hospital | N/A |
| Recruiting | The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA NCT05254431 | VA Office of Research and Development | N/A |
| Completed | CBCT Analysis of the Craniofacial Architecture in Young, Non-overweight Apneic Adult Phenotype NCT06022679 | Centre Hospitalier Universitaire de Liege | — |
| Completed | TUCSON Study: Tackling Underlying Causes of Sleep Related Nocturia Nocturia NCT05404828 | University Hospital, Ghent | — |
| Completed | Effect of Opioids on Central Control of Ventilation in Children With Obstructive Sleep Apnea NCT05051189 | Baylor College of Medicine | EARLY_Phase 1 |
| Active Not Recruiting | Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation NCT04950894 | LivaNova | N/A |
| Recruiting | Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? NCT05094271 | University of California, San Diego | Phase 1 |
| Completed | Changes of the Upper Airway Volume After Orthognathic Surgery NCT05060133 | Lund University Hospital | — |
| Completed | COPD Circuit Exercise NCT05395390 | Texas A&M University | N/A |
| Unknown | Impact of Breathing Route on CPAP Effectiveness to Treat Obstructive Sleep Apnea NCT05272761 | University of Sao Paulo General Hospital | — |
| Completed | Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea NCT04639193 | University of California, San Diego | Phase 2 |
| Unknown | Telemedicine and Humidification for Cpap IN Osas Key Treatment (THINK Study) NCT04300166 | Andrea Romigi | N/A |
| Completed | Predictors of OSA in Patients With COPD NCT05605431 | Cairo University | — |
| Unknown | Comparison for Oral Negative Pressure Therapy and CPAP for OSA Under Sleep Endoscopy Assistance: A Randomized NCT04626700 | Chang Gung Memorial Hospital | N/A |
| Completed | Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea NCT04874727 | Manhattan Beach Orthodontics | — |
| Unknown | The Association Between Sleep Duration and Sleep Disorders and Proteinuria in Children NCT03933046 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | Age and Sleep Apnea Syndrome NCT03885440 | Taipei Veterans General Hospital, Taiwan | — |
| Completed | Validation of a Portable Sleep Device in Patients With Co-existing Medical Illnesses NCT03930316 | Chinese University of Hong Kong | N/A |
| Completed | Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI NCT03664765 | VA Office of Research and Development | N/A |
| Unknown | Evaluation of the Multidimensional Dyspnea Profile (MDP) NCT04090671 | Institut für Pneumologie Hagen Ambrock eV | N/A |
| Unknown | Could HRV be a Valuable Predictor for CPAP Adherence? NCT03721445 | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | — |
| Completed | Efficacy of HFNC as an Alternative to CPAP Therapy in Surgical Patients With Suspected Moderate to Severe OSA NCT05075668 | Changi General Hospital | N/A |
| Completed | Mouth Breathing Habits Improvement Intervention NCT05404438 | National Yang Ming Chiao Tung University | N/A |
| Completed | Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases NCT04903639 | Benha University | — |
| Completed | Evaluation of Left Ventricular Function and Therapeutic Effect of CPAP in Patients With OSAS by 3D STE NCT04957004 | Peking University Third Hospital | — |
| Unknown | Donepezil, Residual Excessive Daytime Sleepiness, Obstructive Sleep Apnea NCT03299257 | Associação Fundo de Incentivo à Pesquisa | Phase 4 |
| Unknown | Maxillomandibular Advancement in the Treatment of Obstructive Sleep Apnea NCT03796078 | Centro Medico Teknon | N/A |
| Completed | OSA Recurrence in CPAP Withdrawal NCT03472612 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | Impact of OSA on Outcomes in Acute Coronary Syndrome NCT03793582 | MetroHealth Medical Center | — |
| Unknown | "Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients NCT03295019 | You First Services | N/A |
| Terminated | Effect of Orofacial Myofunctional Therapy on Mouth Air Leak in Patients With Sleep Apnea Treated With CPAP NCT05432908 | University of Sao Paulo General Hospital | N/A |
| Completed | Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea Syndrome NCT04179942 | Mansoura University | N/A |
| Completed | Efficacy of a Novel MAD in OSA NCT03196583 | Mauro Manconi | N/A |
| Completed | Telemedicine for CPAP Therapy Control in OSA NCT03051724 | Hospital Clinic of Barcelona | N/A |
| Unknown | Long Follow up on Patients With Obstructive Sleep Apnea That Undergo Diagnosis and Surgical Treatment NCT02976207 | Hillel Yaffe Medical Center | — |
| Unknown | The Effect of Exercise on Systemic Inflammation in Veterans With COPD and OSA NCT03431103 | Salem Veterans Affairs Medical Center | N/A |
| Unknown | Evaluation in Patients With Obstructive Sleep Apnea That Had Undergone Diagnosis and Surgical Treatment NCT02977338 | Hillel Yaffe Medical Center | — |
| Completed | Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station NCT02856633 | Cloud DX Inc. | — |
| Completed | Validity of a Vibrating Postural Device for the Treatment of Positional Obstructive Sleep Apnea (Postural) NCT03336515 | Hospital Universitario Araba | N/A |
| Completed | Dimethyl Fumarate for Obstructive Sleep Apnea NCT02438137 | University of Michigan | Phase 2 |
| Completed | A Cross Over Case Control Study of a Vibration Positional Device for Treatment of OSA NCT02613975 | Chinese University of Hong Kong | N/A |
| Completed | PSG Versus Oxim-capnography to Setup Home NIV NCT02444806 | Guy's and St Thomas' NHS Foundation Trust | Phase 2 |
| Unknown | The Role of Endothelium A and EGFR Receptor in Fibrocytes From Asthma With Obstructive Sleep Apnea NCT02749565 | Chang Gung Memorial Hospital | — |
| Completed | Evaluation of the Cardiovascular Effects of the MAS in the Treatment of Obstructive Sleep Apnea NCT02320877 | University Hospital, Antwerp | N/A |
| Completed | Sham CPAP vs. Straight CPAP for Chronic Cough NCT03172130 | Krishna M. Sundar | N/A |
| Completed | Non-Inferiority Study of the FRESCA Mask Versus Existing CPAP Mask for Treatment of Obstructive Sleep Apnea NCT02387476 | FRESCA Medical | N/A |
| Completed | A Post-Market Clinical Trial for Access and Visualization of the Oropharynx, Hypopharynx and Larynx During Tra NCT02262247 | Medrobotics Corporation | — |
| Completed | Exhaled NO as a Biomarker of Gestational OSA and Persistence Postpartum NCT02100943 | Wake Forest University Health Sciences | — |
| Completed | Telemonitoring of CPAP Therapy in Apoplexy Patients With OSA NCT01986452 | Institut für Pneumologie Hagen Ambrock eV | N/A |
| Completed | Continuous Positive Airway Pressure (CPAP) for Primary Care NCT02459548 | Hospital Universitario Araba | N/A |
| Completed | Follow-up of Patients With Obstructive Sleep Apnea in Primary Care. NCT01918449 | Sociedad Española de Neumología y Cirugía Torácica | N/A |
| Completed | Ambulatory Versus Conventional Approach Diagnosing OSA NCT01828216 | Chinese University of Hong Kong | N/A |
| Completed | A Simplified Questionnaire to Detect OSA in COPD Patients NCT01801761 | Chang Gung Memorial Hospital | — |
| Completed | Sleep Apnea and Vascular Function NCT01717339 | Mayo Clinic | N/A |
| Completed | Effect of Rocuronium on the Acute Hypoxic Ventilatory Response in Patients With Obstructive Sleep Apnea NCT01672606 | Malin Jonsson Fagerlund | N/A |
| Completed | Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients NCT01601977 | Patrick Murphy | Phase 2 / Phase 3 |
| Completed | Nasal Pillows vs. Nasal Masks at High CPAP Pressure NCT01690923 | ResMed | N/A |
| Unknown | Efficacy of Adjustable Thermoplastic Oral Appliances in Patient With OSA NCT01466309 | Mahidol University | N/A |
| Completed | Continuous Positive Airway Pressure Use in Asthma With Moderate to Severe Obstructive Sleep Apnea Patients NCT01383564 | Chinese University of Hong Kong | N/A |
| Completed | Randomized Study of Provent Versus Sham Device to Treat Obstructive Sleep Apnea NCT00772044 | Ventus Medical, Inc. | Phase 4 |
| Completed | Adherence to CPAP in Patients With OSA. Ten Year Follow up NCT03644121 | Maugeri Foundation | — |