| Not Yet Recruiting | Comparison of a 3-step Bonding System (Transbond™ XT) and a 2-step System (GC Ortho Connect™) on Demineralizat NCT07355322 | University Hospital, Montpellier | N/A |
| Completed | Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients NCT07254819 | University of Athens | N/A |
| Recruiting | Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Print NCT06944860 | University of Malaya | N/A |
| Recruiting | Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors NCT06814262 | Virginia Commonwealth University | N/A |
| Not Yet Recruiting | Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients NCT06766097 | University of Athens | N/A |
| Recruiting | The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain NCT06573996 | University of the Pacific | N/A |
| Completed | Evaluation of Taste Sensation Changes During Fixed Orthodontic Treatment NCT06989736 | Biruni University | N/A |
| Completed | Derma Pen as Treatment of Gingivitis Induced by Orthodontics NCT06567405 | Safa Basiouny Alawy | N/A |
| Completed | Assessment of Pain When Removing Metallic Brackets for Orthodontic Patients Using Two Removal Methods NCT06873503 | Damascus University | N/A |
| Recruiting | Evaluation of The Stability of Orthodontic Treatment After First Premolar Extraction Using Combined Retention NCT06502886 | Cairo University | N/A |
| Completed | Evaluation Of Anchorage Control Using Arch Wire Stopper Versus Mini-Screws NCT06416904 | Cairo University | N/A |
| Unknown | Fluoride Delivery to Prevent White Spots During Orthodontic Treatment NCT05005689 | Liverpool University Hospitals NHS Foundation Trust | Phase 4 |
| Completed | Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic NCT05825742 | Koite Health Oy | N/A |
| Completed | Orthodontic Treatment Impact on Life Experience of Adolescents With Fixed Orthodontic Appliances NCT06518733 | Cairo University | — |
| Completed | Efficiency of Rigid Versus Non-rigid Indirect Anchorage During Canine Retraction: A Split Mouth Randomized Stu NCT06554769 | Cairo University | N/A |
| Unknown | Alteration of Taste Among Orthodontic Patients Following Clear Aligners Treatment NCT06124742 | Riyadh Elm University | — |
| Recruiting | Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment NCT05733676 | University of Alberta | N/A |
| Unknown | The Effects of Different Storage Conditions on Removable Retainers NCT05854953 | University of Malaya | N/A |
| Completed | Effectiveness of Methods to Remove Residual Orthodontic Adhevsie NCT05929391 | University of Baghdad | N/A |
| Completed | Using Probiotics to Improve Oral Hygiene During Orthodontic Treatment NCT06641960 | Damascus University | N/A |
| Completed | Evaluation of Two Mini-Implant Lengths in the Infra-Zygomatic Crest Region NCT06293872 | University of Baghdad | N/A |
| Completed | ZnO Nanoparticles Coated Orthodontic Molar Tube NCT06089720 | University of Baghdad | N/A |
| Completed | Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles NCT06124235 | University of Baghdad | Phase 3 |
| Completed | Clinical Effectiveness of the Calcium Chloride (CaCl2) Surface- Treated Orthodontic Mini Implant (OMI) NCT06607536 | Universiti Teknologi Mara | N/A |
| Unknown | Assessment of the Effectiveness of Corticision Combined by Selfligating Bracket System on the Acceleration of NCT05604612 | Al-Azhar University | N/A |
| Unknown | Evaluation of Maxillary Canine Retraction Assisted With Two Different Methods of Low-Intensity Pulsed Ultrasou NCT05692817 | Ammar Kasem Alzoubi | N/A |
| Completed | Chios Mastic Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients NCT05647369 | Iosif Sifakakis | N/A |
| Unknown | Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers NCT05644119 | King Abdulaziz University | N/A |
| Completed | Effects of Social Media on Oral Hygiene With Orthodontic Patients NCT06886984 | Karadeniz Technical University | N/A |
| Completed | Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 Malocclusion NCT06403033 | Damascus University | N/A |
| Unknown | Comparison of Precision in Brackets Position in Two Indirect Bonding Materials NCT05483114 | Fundación Universitaria CIEO | N/A |
| Completed | The Validity of Customized Orthodontic Bracket Set up NCT05549089 | Ammar Alubaydi | N/A |
| Unknown | Bracket Failure With a Novel Etchant Paste. A Randomized Clinical Trial NCT05766033 | University of Baghdad | N/A |
| Unknown | Intraoral Maxillary Protraction Technique vs Facemask Using Alt-RAMEC Protocol for Treatment Class III Growing NCT05345756 | Cairo University | N/A |
| Completed | Wear-documentation and Orthodontic Appliance Compliance NCT05213338 | University of Helsinki | N/A |
| Completed | The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients. NCT05651503 | University of Athens | N/A |
| Unknown | Smile Arc Assessment in Orthodontic Patients Following Smile Arc Protection VS MBT Placement Guide Bonding Str NCT05277506 | Cairo University | N/A |
| Unknown | Effect of Moringa Oleifera Mouthwash NCT05191069 | Riphah International University | N/A |
| Completed | Changes in the Upper Airway Volume After Rapid Maxillary Expansion in Adults Using Pure Skeletal Anchorage NCT05831722 | University of Salamanca | — |
| Completed | Quantitative Measurement of ARI NCT05499923 | CMH Lahore Medical College and Institute of Dentistry | N/A |
| Completed | Low Level Laser Therapy Applied in Orthodontic Tooth Movement NCT05695053 | China Medical University Hospital | EARLY_Phase 1 |
| Completed | Assessment of Bacterial Loads of Essix Retainers in Patients Under Retention Therapy NCT04871763 | University of Pavia | N/A |
| Unknown | The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Reten NCT04788550 | University of Malaya | N/A |
| Unknown | Factors Associated With Pain Level Experience in Orthodontic Treatment NCT04834466 | Chia Jung Lee | — |
| Completed | Comparison Between Shear Bond Strength of Different Commercial Metal Bracket Brands: an in Vitro Study NCT05812456 | Future University in Egypt | N/A |
| Unknown | Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodonti NCT04598633 | University of Erlangen-Nürnberg | N/A |
| Completed | Photodynamic Therapy in Patients With Gingivitis NCT04037709 | University of Nove de Julho | N/A |
| Unknown | Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodonti NCT04606186 | University of Erlangen-Nürnberg | N/A |
| Completed | Smartphone Application Based Reminder Therapy in Orthodontic Patients NCT05001490 | Rehman Medical Institute - RMI | N/A |
| Completed | Microbial Colonisation On Vacuum-Formed Retainers Constructed On Conventional Models And Three Dimensional (3D NCT03844425 | University of Malaya | N/A |
| Unknown | The Omission of Pumice Prophylaxis on Bracket Failure Rates Using Self Etch Primers NCT04131855 | University of Malaya | N/A |
| Unknown | Food Reward Circuit Change by Orthodontics NCT05026411 | Bezmialem Vakif University | N/A |
| Terminated | Does Use of the Waterpik Maintain Cleaner Teeth in Patients With Fixed Braces NCT04604262 | York Teaching Hospitals NHS Foundation Trust | N/A |
| Unknown | Influence of Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement and Associated Pain NCT05120102 | Dow University of Health Sciences | N/A |
| Unknown | Evaluation of the Use of Photobiomodulation After the Installation of Elastometric Separators NCT03939988 | University of Nove de Julho | Phase 1 |
| Completed | Effect of Deproteinization on the Shear Bond Strength and Glue Penetration in the Enamel of Orthodontic Bracke NCT05042843 | University Hospital, Montpellier | — |
| Completed | Evaluation of Fixed Mandibular Retainer Using 3D Printed Positioning Tray Versus Direct Bonding Technique NCT03572179 | Raghda Alaa | N/A |
| Completed | Proteomics and Orthodontic Root Resorption NCT04291443 | University of Baghdad | N/A |
| Completed | L Brevis for Traumatic Oral Lesions in Orthodontic Patients NCT04398511 | Universidade de Passo Fundo | Phase 2 |
| Completed | Comparison of Different Methods of Controlling Pain During Debonding of Orthodontic Brackets NCT05104190 | Armed Forces Institute of Dentistry, Pakistan | N/A |
| Unknown | Root Proximity During Mini-Screw Insertion Using a Digital Three-Dimensional Printed Guide NCT03653078 | Cairo University | N/A |
| Unknown | Miniscrews Primary Stability NCT03696511 | University of Genova | N/A |
| Unknown | Accuracy of Digital Three-Dimensional Root Position Prediction Via Digitized Models NCT03552640 | Cairo University | — |
| Completed | Photobiomodulation and Root Resorption NCT04044989 | University of Gaziantep | N/A |
| Unknown | Chairside Time and Bond Failure of Non Custom Versus Custom Base Orthodontic Attachments During Indirect Bondi NCT03365232 | Cairo University | N/A |
| Unknown | Chairside Time and Accuracy of Indirect Bonding of Orthodontic Attachments Using Double Versus Single Transfer NCT03362034 | Cairo University | N/A |
| Completed | The Role of Paracetamol-caffeine and Laser Irradiation on Controlling Pain and Discomfort During Orthodontic T NCT03400111 | Damascus University | N/A |
| Completed | Control of Pain From Braces With Patient Advice Sheets NCT03159520 | University of Dundee | N/A |
| Completed | Motivational Interview and Orthodontic Patients NCT04871373 | Universidad Iberoamericana | N/A |
| Completed | Evaluation of Periodontal Ligament Distraction Using a Modified Surgical Technique for Retraction of Maxillary NCT03535285 | Cairo University | N/A |
| Completed | Bond Failure of Two Types of Molar Buccal Tubes NCT03476161 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | Scalpel Versus Laser Gingivectomy in Orthodontic Patients in the Management of Periodontal Health NCT03514316 | University of Rome Tor Vergata | N/A |
| Completed | A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the E NCT05710874 | University Hospital, Ghent | N/A |
| Completed | The Effect of Using Mobile Applications for Improving Oral Hygiene NCT03109769 | Riyadh Colleges of Dentistry and Pharmacy | N/A |
| Completed | Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans NCT03004196 | Peoples University, Bhanpur, Bhopal | Phase 1 / Phase 2 |
| Completed | Effectiveness of Low Frequency Vibration on the Rate of Canine Retraction NCT05818527 | mohamed abdelmotaleb | N/A |
| Completed | Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion NCT03976635 | Damascus University | N/A |
| Completed | Comparison of Arch Expansion Changes Between Passive Self-ligating and Conventional Brackets NCT03363620 | CES University | Phase 3 |
| Completed | Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device NCT02427763 | Universidade Positivo | EARLY_Phase 1 |
| Unknown | Efficacy of a Novel Fluoride Varnish in Preventing WSL During/After Treatment With Fixed Orthodontic Appliance NCT03725020 | Malmö University | N/A |
| Unknown | Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment NCT02001311 | King Abdulaziz University | Phase 1 |
| Completed | Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response NCT03804034 | Institucion Universitaria Colegios de Colombia | N/A |
| Completed | Stability of Maxillary Anterior Teeth After Two Years of Retention in Adolescents Comparing Two Bonded and a V NCT04616755 | Kronoberg County Council | N/A |
| Completed | SPACE MAINTAINERS EFFECTS ON ORAL MİCROFLORA NCT04749654 | TC Erciyes University | N/A |
| Completed | Evaluation of the Sandblasting on the Rebonding Strength NCT04606043 | Damascus University | N/A |