NCT05695053

Low Level Laser Therapy Applied in Orthodontic Tooth Movement

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: China Medical University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.

Conditions

• Orthodontic Appliance Complication

Interventions

Type	Name	Description
DEVICE	Low Level Laser Therapy	Low level laser therapy could provide energy to trigger cell differentiation.
OTHER	Placebo	Placebo

Timeline

• Start date: 2021-08-27
• Primary completion: 2022-08-26
• Completion: 2023-08-26
• First posted: 2023-01-23
• Last updated: 2025-02-13

Locations

1 site across 1 country: Taiwan