| Recruiting | Sensory Outcomes in Active Substance Users NCT06639438 | Boston Medical Center | — |
| Enrolling By Invitation | Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care NCT06469177 | Nova Scotia Health Authority | N/A |
| Recruiting | Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. NCT06291363 | Ciusss de L'Est de l'Île de Montréal | Phase 4 |
| Unknown | A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders. NCT05995873 | MindLight, LLC | N/A |
| Recruiting | Influence of Nociception Level Monitor (NOL) Guided Analgesic Delivery on Robot-assisted Colorectal Surgery NCT05662371 | University of Southern Denmark | N/A |
| Active Not Recruiting | Patient Utilization of Opioid Destruction Bags in the Post-op Period NCT05875857 | University of Nebraska | N/A |
| Unknown | Pigtail or Chest Tube Placement After Uniportal Video-assisted Thoracoscopic Surgery NCT06050551 | National Cheng-Kung University Hospital | N/A |
| Unknown | Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids NCT05752799 | G.Gennimatas General Hospital | N/A |
| Completed | Observational Study on the Incorporation of Opioids and Their Metabolites Into Hair of Pediatric Patients NCT05740657 | University of Zurich | — |
| Active Not Recruiting | Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement NCT05283980 | Beth Israel Deaconess Medical Center | Phase 2 / Phase 3 |
| Unknown | Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol NCT05242081 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Completed | Pecto-Intercostal Fascial Plane Block Study NCT04928339 | University of Wisconsin, Madison | Phase 4 |
| Completed | Opioid Modulation and Neural Reward Activation in Healthy Adults NCT04854551 | University of Colorado, Denver | Phase 1 / Phase 2 |
| Unknown | Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing NCT04564729 | Brigham and Women's Hospital | N/A |
| Unknown | Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder NCT04275258 | University of Washington | N/A |
| Completed | Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in NCT04219397 | Indiana University | N/A |
| Completed | Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery NCT04081545 | Christine Oryhan | Phase 3 |
| Completed | Comparing Post-Operative Analgesic Effects of PCAM With Dexmedetomidine 1 mcg/ml vs PCAM With Dexmedetomidine NCT05288738 | Universiti Kebangsaan Malaysia Medical Centre | Phase 4 |
| Completed | An Opioid Prescribing Nudge NCT04069403 | Duke University | N/A |
| Completed | Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery NCT03959969 | Medstar Health Research Institute | N/A |
| Completed | Effect of Opioid Shortage on Drug Selection NCT04099030 | Wake Forest University Health Sciences | — |
| Completed | Application of Economics & Social Psychology to Improve Opioid Prescribing Safety (AESOPS): R21 Pilot Phase NCT03773484 | University of Southern California | N/A |
| Completed | Analgesia aNd caNcer recUrrence Lung cAncer Resection NCT04656769 | University of Turin, Italy | — |
| Recruiting | Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes NCT03923374 | Senthil Sadhasivam | — |
| Completed | Nurses' Knowledge and Attitude About Opioids NCT04252443 | European University of Lefke | N/A |
| Completed | Enhancing Medication-based Analgesia in Humans NCT02901275 | Johns Hopkins University | Phase 2 |
| Completed | EMR Defaults to Nudge Opioid Prescribing NCT04155229 | University of California, San Francisco | N/A |
| Terminated | Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac S NCT02747875 | Andrew Waberski | N/A |
| Completed | the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Bl NCT02653144 | Montefiore Medical Center | Phase 4 |
| Completed | The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back NCT02483468 | Medical University of South Carolina | Phase 2 / Phase 3 |
| Completed | EHR-Based Medication Complete Communication Strategy to Promote Safe Opioid Use NCT02431793 | Northwestern University | N/A |
| Completed | Controlled Substance Treatment Agreements in an Internal Medicine Residents' Clinic NCT02244099 | Ohio State University | N/A |
| Completed | Phone Interview to Prevent Recurring Opioid Overdoses NCT02282306 | University of Cincinnati | N/A |
| Completed | Prescribing Opioid Pain Relievers in the Emergency Department: Understanding and Optimizing the Encounter NCT02299024 | Northwestern University | N/A |
| Completed | Anesthesia for Vascular Access Devices NCT04749069 | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | N/A |
| Unknown | Paracetamol for Cancer Pain NCT01313247 | Haraldsplass Deaconess Hospital | Phase 4 |