| Not Yet Recruiting | Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland NCT06426004 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Not Yet Recruiting | Non-invasive Diagnostics of Shunt Obstruction in Adult Hydrocephalus NCT07172841 | Göteborg University | N/A |
| Recruiting | White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH) NCT07103681 | Imperial College London | — |
| Recruiting | Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus NCT06498960 | CereVasc Inc | N/A |
| Recruiting | Proteinopathies Expression in Skin of Neurodegenerative Disorders NCT06528964 | Universidad Autonoma de San Luis Potosí | — |
| Recruiting | European Study of Prodromal iNPH NCT05910944 | Johan Virhammar | — |
| Recruiting | Neurosurgical Outcome Network NCT06724029 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Unknown | Normal Pressure Hydrocephalus Biomarkers Investigation NCT05562596 | University of Roma La Sapienza | — |
| Completed | The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH NCT06857136 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Recruiting | Identifying Gait Changes From a CSF Tap Test Using a Smart Insole in iNPH NCT06722768 | Yonsei University | — |
| Unknown | Normal Pressure Hydrocephalus and Sleep Apnea NCT04471740 | University of Valencia | N/A |
| Terminated | A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synuc NCT04020198 | Stony Brook University | — |
| Unknown | Adjustable Gravitational vs. Adjustable Differential Pressure Valves in iNPH NCT04434053 | Military University Hospital, Prague | N/A |
| Unknown | Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH NCT03877107 | EssaiClinique_PL-HPN | N/A |
| Unknown | Brain Network Activation in Patients With Movement Disorders NCT03269201 | Sheba Medical Center | — |
| Completed | Neurology Inpatient Clinical Education Trial NCT03826056 | Dartmouth-Hitchcock Medical Center | N/A |
| Terminated | CPT-3 in Normal Pressure Hydrocephalus NCT03521518 | Vanderbilt University Medical Center | — |
| Unknown | Acetazolamide for Treating NPH in Shunt-candidates Patients NCT03779594 | Rabin Medical Center | Phase 2 |
| Completed | The Usage of Telemetric Prechamber Sensor Reservoir in Management of Normal Pressure Hydrocephalus. Comparisso NCT06629168 | University Hospital Hradec Kralove | — |
| Unknown | The Brain Structure and Neural Network Changing the Before and After Ventriculo-peritoneal Shunting in the Nor NCT03092804 | Peking Union Medical College Hospital | — |
| Unknown | Endoscopic Third Ventriculostomy Versus Ventriculo-peritoneal Shunting in Idiopathic Normal Pressure Hydroceph NCT03245138 | University Medicine Greifswald | N/A |
| Completed | Cerebrospinal Fluid Proteome in Hydrocephalus NCT02016352 | University Hospital, Toulouse | N/A |
| Completed | A Randomized Cross-over Study for Normal Pressure Hydrocephalus NCT01798641 | Johns Hopkins University | N/A |
| Unknown | Flow MRI in Normal Pressure Hydrocephalus NCT01909960 | Centre Hospitalier Universitaire, Amiens | N/A |
| Unknown | Computerised Testing of Cognitive Response to Cerebrospinal Fluid Shunting in Idiopathic Normal Pressure Hydro NCT01618500 | Umeå University | — |
| Terminated | Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure Hydrocephalus NCT01092546 | GE Healthcare | Phase 3 |
| Completed | PET Imaging of Brain Amyloid in Normal Pressure Hydrocephalus NCT01053312 | GE Healthcare | Phase 3 |
| Withdrawn | ShuntCheck Accuracy in Detecting Shunt Obstruction Normal Pressure Hydrocephalus (NPH) Patients NCT00793416 | NeuroDx Development | Phase 4 |
| Terminated | Conservative Versus Surgical Management of Idiopathic Normal Pressure Hydrocephalus (INPH) NCT00727142 | University College London Hospitals | N/A |
| Completed | Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus NCT00600795 | Vanderbilt University Medical Center | — |
| Completed | Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH) NCT01265251 | Umeå University | — |
| Terminated | Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus NCT00613886 | University of California, Irvine | N/A |
| Completed | Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery NCT01815775 | Centre Hospitalier Universitaire, Amiens | EARLY_Phase 1 |
| Terminated | Anterior Pituitary Function in Patients With Hydrocephalus NCT00149721 | Johns Hopkins University | N/A |
| Completed | Normal Pressure Hydrocephalus (NPH) Registry NCT00233701 | Codman & Shurtleff | — |
| Unknown | European Study on Prediction of Outcome in Patients With Idiopathic Normal Pressure Hydrocephalus NCT00874198 | International Neuroscience Institute Hannover | N/A |
| Completed | A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System. NCT00196196 | Codman & Shurtleff | Phase 3 |