NCT01909960

Flow MRI in Normal Pressure Hydrocephalus

Benefit of Flow Magnetic Resonance Imaging in the Management of Normal Pressure Hydrocephalus

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 144 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Normal pressure hydrocephalus diagnosis based on quantitative study of cerebro-spinal fluid and blood flow by phase contrast magnetic resonance imaging.

Conditions

• Normal Pressure Hydrocephalus

Interventions

Type	Name	Description
OTHER	Flow imaging	Quantitative flow study was performed by 2D phase-contrast velocity-encoded cine MRI (repetition/echo time, 15/7 ms; field of view = 140 x 140 mm²; matrix size = 256 x 128, flip angle = 25 degrees,one excitation, slice thickness = 5 mm). Cerebrospinal fluid and blood flows are measured with a velocity-encoding value of 5-10 cm/s and 80 cm/s respectively. Peripheral gating was used to cover the entire cardiac cycle with retrospective cardiac synchronization of 32 quantitative flow-encoded images per cycle. Clinical examination consists in Larson's score and MMSE

Timeline

• Start date: 2012-05-03
• Primary completion: 2018-09-01
• Completion: 2018-09-01
• First posted: 2013-07-29
• Last updated: 2018-08-10

Locations

2 sites across 1 country: France