Clinical Trials Directory

Trials / Conditions / Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

137 registered clinical trials studyying Non-alcoholic Steatohepatitis19 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingA Safety, Tolerability, Pharmacokinetics/Pharmacodynamics Study of HEC169584 Capsules in Healthy Subjects
NCT07099118
Sunshine Lake Pharma Co., Ltd.Phase 1
RecruitingEffect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
NCT06138821
Pichamol Jirapinyo, MD, MPHN/A
CompletedSafety, Tolerability, and Pharmacokinetics of ACT500 in Healthy Adult Participants
NCT06716905
Xiamen Amoytop Biotech Co., Ltd.Phase 1
RecruitingIdentification of Liver Fibrosis Biomarkers
NCT06819917
Roche Diagnostics GmbH
Not Yet RecruitingStudy of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for
NCT06160271
Central Hospital, Nancy, FrancePhase 2
RecruitingEffect of Alternate Day Fasting Over Standard Medical Management Alone to Reverse Non-alcoholic Steatohepatiti
NCT06676813
Institute of Liver and Biliary Sciences, IndiaN/A
Enrolling By InvitationReducing Non-Alcoholic Steatohepatitis
NCT06519448
Military University Hospital, PragueN/A
CompletedUltrasound and Attenuation Imaging
NCT06552377
Hywel Dda Health Board
CompletedClinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis
NCT06105060
Beni-Suef UniversityEARLY_Phase 1
CompletedA Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)
NCT06052566
Merck Sharp & Dohme LLCPhase 1
WithdrawnAssessment of Fatty Liver With Thermo-acoustic Device
NCT04302051
Medical College of Wisconsin
UnknownEffect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory
NCT05751720
Dr Adnan AghaPhase 1 / Phase 2
CompletedStudy to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH
NCT06054815
NeuroBo Pharmaceuticals Inc.Phase 2
RecruitingEfficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjec
NCT06569524
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.Phase 2
RecruitingA Study of INI-822 in Healthy Volunteers and Participants with Non-alcoholic Steatohepatitis (NASH) or Presume
NCT05945537
Inipharm Australia Pty LtdPhase 1
Unknownthe Efficacy and Safety of Diosmin on Non-diabetic Patients With Non-alcoholic Steatohepatitis.
NCT05942547
Tanta UniversityPhase 3
CompletedA Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD9550 Following Single Ascending Dose Ad
NCT05848440
AstraZenecaPhase 1
CompletedA Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic I
NCT05835180
Sagimet Biosciences Inc.Phase 1
RecruitingInAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
NCT05463796
Dana-Farber Cancer Institute
RecruitingSynbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis
NCT05821010
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Phase 2
CompletedA Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combinatio
NCT05766709
Novo Nordisk A/SPhase 1
CompletedPhase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH
NCT06297434
J2H BiotechPhase 2
TerminatedA Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants
NCT05668936
AstraZenecaPhase 1
CompletedInvestigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females
NCT06308874
J2H BiotechPhase 1
RecruitingCHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome
NCT05623150
Institut National de la Santé Et de la Recherche Médicale, France
UnknownComparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcohol
NCT05605158
Tanta UniversityPhase 3
Active Not RecruitingStudy to Evaluate the Safety, Tolerability, and Efficacy of ASC41 Tablets in Adult Patients With NASH
NCT05462353
Gannex Pharma Co., Ltd.Phase 2
RecruitingSoluble Fibre Supplementation in NAFLD
NCT05480696
McMaster UniversityPhase 2
Active Not RecruitingComparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuric
NCT05574036
Tanta UniversityPhase 2
UnknownOmics-based Predictors of NAFLD/Potential NASH
NCT05301231
National Research Centre, Egypt
UnknownFirst-in-Human Study of GM-60106 in Healthy Adults and Otherwise Healthy Adults With an Increased Body Mass In
NCT05517564
JD Bioscience Inc.Phase 1
CompletedEfficacy and Safety of Dapagliflozin in Patients with Non-alcoholic Steatohepatitis
NCT05254626
Cairo UniversityPhase 2
UnknownFecal Microbiota Transplantation for the Treatment of Non-Alcoholic Steatohepatitis
NCT03803540
Puerta de Hierro University HospitalPhase 1
CompletedNutritional Cognitive Behavioral Therapy Feasibility Study in NAFLD and NASH
NCT05357248
Better TherapeuticsN/A
CompletedA Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy
NCT05294458
AstraZenecaPhase 1
CompletedEffect of Adjustable Intragastric Balloon in Obese Non-alcoholic Fatty Liver Disease
NCT04182646
Asian Institute of Gastroenterology, IndiaN/A
CompletedA Study to Assess the Safety and Tolerability of LB-P6 and LB-P8 in Healthy Participants
NCT05053165
LISCure BiosciencesPhase 1
CompletedA Safety, Tolerability, Efficacy, and Pharmacokinetics Study of HEC96719 in Subjects With Non-Cirrhotic Non-Al
NCT05397379
Sunshine Lake Pharma Co., Ltd.Phase 2
Active Not RecruitingThe Effect of Aerobic and Resistant Exercise Training in Patients With Non-Alcoholic Steatohepatitis
NCT05065593
Hacettepe UniversityN/A
Active Not RecruitingComparative Study Between Obeticholic Acid Versus Vitamin E in Patients with Non-alcoholic Steatohepatitis
NCT05573204
Tanta UniversityPhase 2
CompletedResearch Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non
NCT05016882
Novo Nordisk A/SPhase 2
UnknownMLCT Oil for Fatty Liver - PASS Trial
NCT05217745
National University Hospital, SingaporeN/A
CompletedStudy of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis
NCT04669158
Stanford UniversityPhase 1 / Phase 2
CompletedMobile Health Delivered Lifestyle Intervention Program in Patients With NASH
NCT04872777
Milton S. Hershey Medical CenterN/A
RecruitingEndoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
NCT05728697
Brigham and Women's Hospital
CompletedThe Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of HEC88473 in Healthy Subjects
NCT04829123
Dongguan HEC Biopharmaceutical R&D Co., Ltd.Phase 1
CompletedA 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy V
NCT04931147
Redx Pharma LtdPhase 1
Active Not RecruitingResearch Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
NCT04822181
Novo Nordisk A/SPhase 3
UnknownPlant Stanols and Liver Inflammation in Overweight and Obese Children
NCT04783116
Maastricht University Medical CenterN/A
CompletedPediatric Liver Fat Quantification (LFQ) Phase 2 Pilot Study
NCT04800094
Philips Clinical & Medical Affairs GlobalN/A
CompletedA Research Study Looking at How the Medicine NNC0194-0499 Behaves in Japanese and Non-Asian Men
NCT04722653
Novo Nordisk A/SPhase 1
WithdrawnSafety and Tolerability of Yaq-001 in Patients With Non-Alcoholic Steatohepatitis
NCT03962608
Yaqrit LtdN/A
Recruiting"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors
NCT04690972
Institut National de la Santé Et de la Recherche Médicale, France
CompletedClinical Performance of LIVERFASt Test Compared w/ Liver Biopsy in Patients w/ NAFLD.
NCT04579874
Fibronostics USA, IncN/A
CompletedUltrasound-Based Liver Fat Quantification (LFQ) Pilot Study
NCT04657523
Philips Clinical & Medical Affairs GlobalN/A
RecruitingIntegrated Diagnostics for Early Diagnosis of Liver Disease
NCT04666402
Manchester University NHS Foundation Trust
RecruitingThe Olmsted NAFLD Epidemiology Study (TONES)
NCT04365855
Mayo ClinicN/A
TerminatedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participa
NCT04171765
Genentech, Inc.Phase 2
CompletedThe Role of Immune Semaphorins in NAFLD
NCT04573543
University Hospital for Infectious Diseases, Croatia
CompletedInvestigate Safety, Tolerability, PK/PK of J2H 1702 in Healthy Males
NCT06308861
J2H BiotechPhase 1
CompletedThe Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Subjects
NCT04422496
Sunshine Lake Pharma Co., Ltd.Phase 1
UnknownHyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease
NCT06176079
Michael Ohliger, MD PhD
UnknownTo Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patien
NCT03950505
Yonsei UniversityPhase 4
CompletedStudy of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NAS
NCT04202354
Arrowhead PharmaceuticalsPhase 1 / Phase 2
TerminatedA Randomized, Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Pr
NCT04378010
Enanta Pharmaceuticals, IncPhase 2
CompletedVitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (P
NCT04198805
Naga P. ChalasaniPhase 2
WithdrawnNASH-FITTER: Nonalcoholic Steatohepatitis Fitness Intervention Treatment Targeting Endothelial Dysfunction Rev
NCT03864835
Milton S. Hershey Medical CenterN/A
CompletedA Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693,
NCT04142424
AstraZenecaPhase 1
CompletedGlucagon Resistance in Patients With NAFLD
NCT04042142
University of AarhusN/A
CompletedEfficacy and Safety of Montelukast in Non Alcoholic Steatohepatitis (NASH)
NCT04537780
Tanta UniversityPhase 4
RecruitingNon-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD
NCT03884075
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Phase 2
CompletedA Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alc
NCT03969719
PfizerPhase 2
TerminatedElafibranor, PK and Safety in Children and Adolescents 8 to 17 Years of Age With Non Alcoholic Steatohepatitis
NCT03883607
GenfitPhase 2
CompletedA Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage
NCT03987451
Novo Nordisk A/SPhase 2
CompletedSaroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis
NCT03863574
Zydus Therapeutics Inc.Phase 2
CompletedEffect of Patient Demographics, Comorbidities, and Medications on Severity of NASH Fibrosis
NCT05357352
Methodist Health System
WithdrawnAssessment of the Safety and Effect of SAR425899 Versus Placebo for the Treatment of Non-alcoholic Fatty Liver
NCT03437720
SanofiPhase 2
UnknownInvestigation on the Role of Gut-liver Axis for Non-alcoholic Steatohepatitis Through Bariatric Surgery
NCT04501042
National Taiwan University Hospital
CompletedStructured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver
NCT03839082
University of MichiganN/A
CompletedSafety, Tolerability, Pharmacokinetics and Efficacy of EYP001a in Patients With Nonalcoholic Steatohepatitis (
NCT03812029
Enyo PharmaPhase 2
CompletedBariatric Surgery Versus Non-alcoholic Steato-hepatitis
NCT03524365
Catholic University of the Sacred HeartN/A
CompletedAn Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis
NCT03656068
Pinnacle Clinical Research, PLLCPhase 2
CompletedExpanding Donor Pool for Live Donor Liver Transplantation: Utilization of Donors With NASH After Optimization
NCT04571957
Institute of Liver and Biliary Sciences, India
RecruitingPrognostic Significance of Fatty Liver Disease in Bariatric Patients
NCT03535142
Esbjerg Hospital - University Hospital of Southern DenmarkN/A
CompletedTherapeutic And Dietary Effects Of The Sublimated Mare's Milk Supplement In Patients With Non-Alcoholic Steato
NCT03664596
Medical Centre Hospital of the President's Affairs Administration, Republic of KazakhstanN/A
Completed2-Week Study In People With Nonalcoholic Fatty Liver Disease
NCT03513588
PfizerPhase 1
CompletedTechnical Validation of MR Biomarkers of Obesity-Associated NAFLD
NCT03674528
University of Wisconsin, Madison
CompletedA Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alco
NCT03421431
Enanta Pharmaceuticals, IncPhase 2
UnknownThe Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Non-alcoholic Fatty
NCT03734510
National Nutrition and Food Technology InstituteN/A
CompletedCoffee Consumption and NASH in the French Population.
NCT03432377
Versailles Hospital
RecruitingEuropean Paediatric Non-Alcoholic Fatty Liver Disease Registry (EU-PNAFLD)
NCT04190849
Cambridge University Hospitals NHS Foundation Trust
UnknownEfficacy and Safety of Berberine in Non-alcoholic Steatohepatitis
NCT03198572
Fudan UniversityPhase 4
CompletedRepeatability and Reproducibility of Multiparametric MRI
NCT03743272
Perspectum
UnknownThe Effects of Hesperidin and Flaxseed on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver
NCT03377153
National Nutrition and Food Technology InstituteN/A
UnknownThe Effects of Hesperidin on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease
NCT03377140
National Nutrition and Food Technology InstituteN/A
CompletedEUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and Obesity
NCT02880189
Mayo ClinicN/A
CompletedInvestigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placeb
NCT02970942
Novo Nordisk A/SPhase 2
TerminatedVolixibat (SHP626) in the Treatment of Adults With Nonalcoholic Steatohepatitis (NASH)
NCT02787304
Mirum Pharmaceuticals, Inc.Phase 2
CompletedPhase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)
NCT02912260
Madrigal Pharmaceuticals, Inc.Phase 2
CompletedEmricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension
NCT02960204
HistogenPhase 2
CompletedA Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH
NCT02784444
Cirius Therapeutics, Inc.Phase 2
CompletedAssessing Kids for Liver Inflammation and Fibrosis Using Non-invasive MRI
NCT03198104
Perspectum
UnknownFecal Microbiota Therapy Versus Standard Therapy in NASH Related Cirrhosis.
NCT02721264
Institute of Liver and Biliary Sciences, IndiaN/A
CompletedOpen-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects
NCT02681055
MediciNovaPhase 2
CompletedEmricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis
NCT02686762
Conatus Pharmaceuticals Inc.Phase 2
UnknownAtorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis
NCT01617772
Tehran University of Medical SciencesPhase 2
CompletedA Study to Investigate How the Study Drug SHP626 is Eliminated From the Body After One Dose
NCT02571192
Mirum Pharmaceuticals, Inc.Phase 1
CompletedThe Effect of HIT in Patients With Non-alcoholic Fatty Liver Disease/Steatohepatitis
NCT02528305
University of BathN/A
TerminatedThe Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) in Adults
NCT03142867
The Geneva Foundation
WithdrawnClinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepat
NCT02541045
Hospital General de MexicoPhase 3
CompletedA Study of BMS-986036 in Subjects With Non-Alcoholic Steatohepatitis (NASH)
NCT02413372
Bristol-Myers SquibbPhase 2
CompletedA Sub-study of BMS-986036 in Subjects With Non-Alcoholic Steatohepatitis (NASH)
NCT03400163
Bristol-Myers SquibbPhase 2
CompletedA Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NAS
NCT02279524
Galmed Research and Development, Ltd.Phase 2
CompletedEffect of Non-Alcoholic Steatohepatitis (NASH) on the Pharmacokinetics of 99mTechnetium-Mebrofenin
NCT02235233
University of North Carolina, Chapel HillPhase 1
CompletedBREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH
NCT02314026
Meridian Bioscience, Inc.Phase 2
CompletedSafety and Tolerability Study of SHP626 in Overweight and Obese Adults
NCT02287779
Mirum Pharmaceuticals, Inc.Phase 1
UnknownThe Effect of Synbiotics Supplement on Lipid Profile, Liver Enzymes, Inflammatory Factors and Hepatic Fibrosis
NCT02530138
National Nutrition and Food Technology InstitutePhase 2 / Phase 3
CompletedThe Effects of Flaxseed Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic F
NCT02395900
National Nutrition and Food Technology InstitutePhase 2 / Phase 3
CompletedThe Efficacy of S-adenosyl Methionine (SAMe) Versus Pentoxiphylline in Patients With Non-alcoholic Steatohepat
NCT02231333
Institute of Liver and Biliary Sciences, IndiaN/A
UnknownUnravelling Mechanisms of Fructose vs Glucose Consumption in the Pathogenesis and Progression of NAFLD
NCT02075164
Prof. Michael Trauner, MDN/A
CompletedEzetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis
NCT01766713
University of California, San DiegoPhase 2
CompletedNon Invasive Measurements of Fibrosis, Inflammation and Steatohepatitis in Morbidly Obese Patients
NCT01695083
Assistance Publique - Hôpitaux de Paris
CompletedThe Effects of Synbiotics Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic
NCT01791959
National Nutrition and Food Technology InstitutePhase 2 / Phase 3
CompletedImpact of Fructose Consumption on Intestinal Permeability in Non-alcoholic Fatty Liver Disease (NAFLD) - a Pil
NCT01696487
Medical University of ViennaN/A
WithdrawnVitamin E Versus Vitamin E Plus Pentoxiphyllin in Patients With Nonalcoholic Steatohepatitis: A Prospective Ra
NCT01279434
Institute of Liver and Biliary Sciences, IndiaN/A
WithdrawnPentoxiphylline and Vitamin E Versus Vitamin E in Patients With Non- Alcoholic Steatohepatitis
NCT01384578
Institute of Liver and Biliary Sciences, IndiaPhase 3
CompletedGlucose-induced Glucagon-like Peptide 1 (GLP-1) Secretion in NAFLD Patients Compared to Healthy Controls
NCT01674972
University Hospital, Basel, Switzerland
CompletedThe Impact of Deferasirox on Non-Alcoholic-Steatohepatitis
NCT01278056
Crolll GmbhPhase 1 / Phase 2
CompletedEffect of Fish-oil on Non-alcoholic Steatohepatitis (NASH)
NCT01056133
Johane AllardPhase 2
CompletedThe Effect of Protandim on Non-alcoholic Steatohepatitis
NCT00977730
University of Colorado, DenverN/A
TerminatedEltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocyto
NCT00678587
GlaxoSmithKlinePhase 3
WithdrawnDevelopment of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children
NCT00677183
Medical College of Wisconsin
CompletedPhase II Trial of Silymarin for Non-Cirrhotic Patients With Non-Alcoholic Steatohepatitis
NCT00680407
Madaus IncPhase 2
CompletedA Proof-of-principle Study of Oral Treatment of Non-alcoholic Steatohepatitis With a Novel PDE4 Inhibitor ASP9
NCT00668070
Astellas Pharma IncPhase 2
CompletedOmega 3 Fish Oil Supplements vs. Placebo for Patients With Non-alcoholic Steatohepatitis (NASH)
NCT00681408
University of VirginiaPhase 2 / Phase 3
CompletedIntragastric Balloon for Treatment of Non Alcoholic Steatohepatitis (NASH)
NCT01761370
National University Hospital, SingaporeN/A
CompletedA One-Year, Randomized, Double-Blind, Placebo-Controlled Trial of Rosiglitazone in Non-Alcoholic Steatohepatit
NCT00492700
Association pour la Recherche sur les Maladies Hépatiques ViralesPhase 2