| Not Yet Recruiting | Sublobar Wedge Resection or Stereotactic Radiotherapy Treatment of High-risk Patients With Early-stage Lung Ca NCT07432802 | Aarhus University Hospital | N/A |
| Not Yet Recruiting | Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLC NCT07405190 | Massachusetts General Hospital | Phase 2 |
| Not Yet Recruiting | Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutat NCT07436858 | The Netherlands Cancer Institute | Phase 1 |
| Not Yet Recruiting | Postoperative Pulmonary Function Assessment Based on Deep Learning Study NCT07256457 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | Phase 1B Trial of Intratumoral Cisplatin for Stage IV Lung Cancer NCT07495098 | University of Vermont | Phase 1 |
| Not Yet Recruiting | Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 NCT07450183 | Henry Ford Health System | Phase 2 |
| Not Yet Recruiting | Osimertinib Plus Capivasertib in NSCLC With PIK3CA/AKT1/PTEN Alterations Following Prior 1L Osimertinib NCT07486648 | Shanxi Province Cancer Hospital | Phase 1 / Phase 2 |
| Not Yet Recruiting | Immune Response to Immunotherapy in Lung Cancer: Study of Sputum and Blood Samples NCT07163507 | University Hospital, Tours | N/A |
| Not Yet Recruiting | Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanc NCT07489066 | Pfizer | Phase 2 |
| Not Yet Recruiting | GCC 2546- Motion Management NCT07398209 | University of Maryland, Baltimore | N/A |
| Not Yet Recruiting | Tunlametinib Combination Therapy in KRAS-Mutated Unresectable Locally Advanced or Metastatic Non-Small Cell Lu NCT07463677 | Sun Yat-sen University | Phase 2 |
| Not Yet Recruiting | Phase II Neoadjuvant Study of Garsorasib Followed by Ivonescimab Plus Chemotherapy in Resectable Stage IIA-III NCT07472478 | Guangdong Provincial People's Hospital | Phase 2 |
| Not Yet Recruiting | Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural Effusion NCT07482605 | Jiangmen Central Hospital | Phase 2 |
| Not Yet Recruiting | Study of Three Endpoints to Assess the Benefit of Rehabilitation in Patients With Advanced Non-small Cell Lung NCT07434947 | University Hospital, Grenoble | — |
| Recruiting | Engagement of Veterans With Lung Cancer NCT07219251 | Palo Alto Veterans Institute for Research | N/A |
| Recruiting | Local Ablative Therapy to Oligoresidual Metastasis in EGFR Mutated Non-small Cell Lung Cancer NCT07379476 | Chinese University of Hong Kong | Phase 2 |
| Not Yet Recruiting | PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor NCT07442292 | Peking University Cancer Hospital & Institute | — |
| Not Yet Recruiting | SL-28 for Advanced Solid Tumours NCT07341737 | Second Life Therapeutics | Phase 1 / Phase 2 |
| Recruiting | Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors NCT07349537 | Revolution Medicines, Inc. | Phase 1 |
| Recruiting | A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint NCT07103395 | Sun Yat-sen University | Phase 2 |
| Not Yet Recruiting | Prediction of Targeted Therapy Efficacy in EGFR-mutant Lung Cancer Patients Using AI-based Multimodal Data NCT07287904 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Recruiting | The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and NCT06717295 | Javier Toledo | — |
| Completed | easyEndoTM Powered in Thoracic Surgery NCT07353489 | Ezisurg Medical Co. Ltd. | N/A |
| Recruiting | Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC NCT07120282 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 2 |
| Not Yet Recruiting | A Real-World Study of IBI351 for KRAS G12C+ NSCLC in China NCT07198620 | Guangdong Association of Clinical Trials | — |
| Not Yet Recruiting | An Open-label, Single-arm Clinical Study of Stapokibart Injection in Combination with Tislelizumab Injection i NCT06883552 | Sichuan University | Phase 2 |
| Recruiting | A Study of PHN-012 in Patients With Advanced Solid Tumors NCT07127874 | Pheon Therapeutics | Phase 1 |
| Recruiting | Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects NCT06800586 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Recruiting | Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study NCT07042724 | Universita di Verona | N/A |
| Recruiting | High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Seg NCT07213375 | Rigshospitalet, Denmark | Phase 2 / Phase 3 |
| Recruiting | A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic So NCT07181473 | Phrontline Biopharma | Phase 1 |
| Not Yet Recruiting | Lorlatinib in ROS1+ NSCLC With Brain Metastasis NCT07083687 | Hunan Cancer Hospital | Phase 2 |
| Not Yet Recruiting | Zusanli (ST36) Electroacupuncture Treatment for Neoadjuvant Immunotherapy in Non-Small Cell Lung Cancer NCT07076836 | West China Hospital | N/A |
| Completed | Tubeless VATS for Lung Cancer Surgery NCT07057531 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Active Not Recruiting | THE EFFECT OF CALISTHENIC EXERCISES ON FATIGUE AND EXERCISE ATTITUDES IN PATIENTS WITH LUNG CANCER NCT07237503 | Hasan Kalyoncu University | N/A |
| Active Not Recruiting | Generation of Reactive T Cells Based on Tumor Whole Cell Antigen Nanovaccines NCT07239544 | The First Affiliated Hospital of Soochow University | — |
| Active Not Recruiting | Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung NCT07202260 | The Christie NHS Foundation Trust | — |
| Not Yet Recruiting | AI-Based Ultrasound Prediction Model for Intracranial Pressure and Prognosis in Lung Cancer Patients With Lept NCT07005791 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Recruiting | Neoadjuvant Sugemalimab + Chemotherapy Followed by Adjuvant Sugemalimab for Patients With Resectable Stage II- NCT06987734 | Shanghai Pulmonary Hospital, Shanghai, China | Phase 2 |
| Not Yet Recruiting | Physical Activity During Chemo- and/or Immunotherapy for Lung Cancer NCT06993896 | University Hospital Schleswig-Holstein | — |
| Recruiting | Application Research of Methylation Markers in Early-stage Lung Cancer Patients Treated With Co-ablation Syste NCT07257471 | Beijing Haidian Hospital | — |
| Recruiting | Inflammation, Cachexia and Therapeutic Response in Lung Cancer Treated With Immune Checkpoint Inhibitors: Expl NCT07004868 | University Hospital, Tours | — |
| Not Yet Recruiting | A Prospective Study: the Impact of Sleep Disturbances on Immunotherapy in Patients With Lung Cancer NCT06953765 | Shanghai Zhongshan Hospital | — |
| Recruiting | Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Ra NCT06987890 | Brigham and Women's Hospital | N/A |
| Recruiting | A Study of SH009 Injection in Patients With Advanced Solid Tumors. NCT07390838 | Nanjing Sanhome Pharmaceutical, Co., Ltd. | Phase 1 |
| Not Yet Recruiting | Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGF NCT06918782 | The University of Hong Kong | Phase 2 |
| Not Yet Recruiting | MWA With or Without Furmonertinib for Early-Stage Non-Small Cell Lung Cancer NCT06969781 | Shanghai Chest Hospital | N/A |
| Withdrawn | Predictive Value of PET/CT for Efficacy of Neoadjuvant Immunotherapy in Non-small Cell Lung Cancer NCT06895941 | Shanghai Pulmonary Hospital, Shanghai, China | — |
| Recruiting | A Study of Orally Administered JBI-802 Alone or in Combination With Pembrolizumab for Patients With Non-small NCT07207395 | The Christ Hospital | Phase 2 |
| Recruiting | Postoperative EGFR-TKI Therapy forContralateral Pulmonary Nodules in Patients With EGFR-Mutant NSCLC（ARMOR2501 NCT06924398 | Sun Yat-sen University | Phase 2 |
| Active Not Recruiting | Interventional Ablation for Early-stage Lung Cancer NCT07005999 | Guangzhou Institute of Respiratory Disease | — |
| Recruiting | Application of Methylation Markers in Early Detection and MRD Monitoring of Lung Cancer NCT07257458 | Beijing Haidian Hospital | — |
| Recruiting | Ultrasound-guided Cryobiopsy of Mediastinal/Hilar Lymph Nodes NCT06921681 | University of Zurich | N/A |
| Not Yet Recruiting | Effectiveness of Respiratory Muscle Training with a Mobile Application After Lobectomy NCT06813144 | Hacettepe University | N/A |
| Active Not Recruiting | A Clinical Study of Furmonertinib in the Treatment of EGFR-Mutated NSCLC With Leptomeningeal Metastases NCT06926803 | Qiming Wang | — |
| Recruiting | Study of Longitudinal Plasma PD-L1 Testing With Immunotherapy in Lung Cancer NCT06849518 | Ballad Health | N/A |
| Recruiting | Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC NCT06771960 | Guangdong Provincial People's Hospital | — |
| Recruiting | Prehabilitation for Patients Undergoing Lung Cancer Surgery NCT06716437 | University of Melbourne | N/A |
| Recruiting | TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients NCT06455917 | University Hospital, Basel, Switzerland | Phase 2 |
| Recruiting | Liquid Biopsy Assay of EBUS-TBNA Supernatant Fluid for Diagnosing Lung Cancer NCT06889467 | Barzilai Medical Center | — |
| Enrolling By Invitation | Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature NCT06332131 | Abramson Cancer Center at Penn Medicine | — |
| Recruiting | Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Centrally Located Early-stag NCT06730295 | Sun Yat-sen University | Phase 2 |
| Recruiting | Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC NCT06663306 | Shanghai Chest Hospital | Phase 1 |
| Active Not Recruiting | Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery. NCT07002788 | Hacettepe University | N/A |
| Recruiting | Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeuti NCT06926179 | Peking University Cancer Hospital & Institute | — |
| Completed | Comparison of SPECT/CT Perfusion and Volumetric CT Volume NCT06600204 | Central Hospital, Nancy, France | — |
| Recruiting | Preoperative Amivantamab or Amivantamab and Carboplatin/Pemetrexed Treatment in Patients With Resectable Non-s NCT06784791 | University Hospital, Essen | Phase 2 |
| Enrolling By Invitation | Cryobiopsy Vs. Forceps Biopsy for Peripheral Pulmonary Lesions NCT06752395 | Pusan National University Hospital | N/A |
| Recruiting | Stereotactic Body Radiotherapy Followed by Tislelizumab Plus Platinum-based Chemotherapy Versus Tislelizumab P NCT06598527 | Yang Hong | Phase 3 |
| Not Yet Recruiting | A Clinical Trial of Furmonertinib Combination Therapy As Neoadjuvant Treatment in Resectable EGFR-Mutated NSCL NCT06585644 | Shanghai Pulmonary Hospital, Shanghai, China | Phase 2 |
| Not Yet Recruiting | Microplastics in the Human Respiratory System NCT06603675 | Wielkopolskie Centrum Pulmonologii i Torakochirurgii | — |
| Not Yet Recruiting | Association Between Microbiome and the Efficacy and Safety of PD-1/PD-L1 Blockade in Resectable NSCLC NCT06613308 | Capital Medical University | — |
| Active Not Recruiting | Advance Care Planning Impact on the Consistency of Older Adults With Lung Cancer and Their Potential Surrogate NCT06616909 | National Taiwan University Hospital | N/A |
| Completed | Mobilization Before and After Video-Assisted Thoracoscopic Surgery Lobectomy/Segmentectomy NCT07338474 | Rigshospitalet, Denmark | — |
| Completed | Real-Time Non-Invasive Localization for Multiple Lung Nodules NCT07257549 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Recruiting | Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter NCT06634979 | Fudan University | N/A |
| Recruiting | A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs NCT06228326 | Krystal Biotech, Inc. | Phase 1 / Phase 2 |
| Recruiting | Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-sma NCT06786468 | Mahidol University | N/A |
| Recruiting | Establishing a Longitudinal Cohort Study of Lung Cancer Using Tissue and Peripheral Blood Metabolomics. NCT06843707 | The First Affiliated Hospital of Guangzhou Medical University | — |
| Recruiting | XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. NCT06792435 | Evopoint Biosciences Inc. | Phase 1 / Phase 2 |
| Recruiting | Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform NCT05520099 | Elephas | — |
| Active Not Recruiting | Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery NCT06663020 | Caner İşevi, MD | — |
| Recruiting | Oral Metronomic Vinorelbine and PD-1 Inhibitors in Elderly Non-small Cell Lung Cancer NCT07041320 | Anhui Chest Hospital | — |
| Active Not Recruiting | Comprehensive Prospective Comparison Of Two Robotic Platforms In Anatomical Lung Resections: Clinical Outcomes NCT07537556 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | — |
| Recruiting | DC/NK Cell Therapy NCT07202611 | National Taiwan University Clinical Trial Center | Phase 2 |
| Completed | Perioperative and Postoperative Circulating Tumor Cell Monitoring in Different Stage of NSCLC NCT07186855 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | — |
| Recruiting | Magnetic Resonance Imaging of the Lung: Oncological Applications NCT07486219 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Active Not Recruiting | Survival Analysis and Prognostic Biomarker Exploration of Postoperative Adjuvant Therapy Patterns in Patients NCT07256002 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | — |
| Recruiting | Development of New Methodologies and Innovative Tools for the diagnoSi and Therapeutic Treatment of uMAni Epit NCT06939049 | ASL Lecce | — |
| Completed | Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors NCT02552121 | Seagen Inc. | Phase 1 / Phase 2 |
| Completed | Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Plus Paclitaxel and Carbopl NCT02279732 | Bristol-Myers Squibb | Phase 3 |
| Completed | Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors NCT02001623 | Seagen Inc. | Phase 1 / Phase 2 |