| Not Yet Recruiting | Effects of Meal Macronutrients on Postprandial Lipids NCT07313787 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Recruiting | Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD) NCT05996536 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Recruiting | Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE" NCT06236932 | Federico II University | N/A |
| Completed | Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management NCT05930106 | TJ Plast Advanced Center for Plastic Surgery | N/A |
| Completed | Performance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling Treatment NCT06089759 | Aesthetic Group | — |
| Unknown | Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects NCT06107439 | Centre Hospitalier Universitaire de la Réunion | N/A |
| Recruiting | Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients NCT05789251 | Centre Hospitalier Universitaire de la Réunion | N/A |
| Recruiting | Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodyst NCT05419037 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Intraoperative Fluid Management of Liposuction , Cardiometry Versus Rohrich Formula NCT05402982 | Ahmed Abdel Wahed Ali | N/A |
| Unknown | Evaluating the Performance and Safety of the Medical Device Plenhyage® in the Treatment of Dermal Tissue Defec NCT05239117 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Unknown | Evaluating the Performance and Safety of the Medical Device Auralya® in the Treatment of Facial Dermal Tissue NCT05239130 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Evaluating the Performance and Safety of the Medical Device Janesse in the Treatment of Facial Dermal Tissue D NCT05239156 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue NCT05239351 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Exploratory Study of the Relationships Between the Biomarkers of Inflammation, Lipidome and Insulin Resistance NCT05424913 | Centre Hospitalier Universitaire de la Réunion | N/A |
| Unknown | Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in P NCT04860063 | Hospital Civil de Guadalajara | Phase 3 |
| Completed | Hemoglobin Level, Coagulopathy Profile and Electrolyte Balance NCT04656054 | Alaa Hassan M. Elhawary | — |
| Recruiting | Low Energy Diet and Familial Partial Lipodystrophy NCT03900286 | Cambridge University Hospitals NHS Foundation Trust | N/A |
| Completed | The PREFORM Study: Rotational Fractional Resection for Submental Contouring NCT03966924 | Recros Medica, Inc. | N/A |
| Completed | Insulin Regulated Amino Peptidase in Patients With Familial Lipodystrophy of DUNNIGAN NCT04578379 | Centre Hospitalier Universitaire de la Réunion | — |
| Completed | Growth Hormone Dynamics and Cardiac Steatosis in HIV NCT03826160 | Massachusetts General Hospital | — |
| Completed | CONFORM: Rotational Fractional Resection for Submental Contouring NCT03407313 | Recros Medica, Inc. | N/A |
| Completed | Shock Waves for Treatment of Gynoid Lipodystrophy and Localized Fat NCT03275259 | Indústria Brasileira Equipamentos Médicos - IBRAMED | N/A |
| Completed | The Cleveland Cardiometabolic Cohort NCT03059121 | University Hospitals Cleveland Medical Center | — |
| Completed | Prevalence of Lipodystrophy Syndrome and Its Role as Cause of Metabolic Disturbances NCT02614027 | Asociacion para el Estudio de las Enfermedades Infecciosas | — |
| Completed | Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Exten NCT02639286 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Unknown | Role of Mesenchymal Stem Cells in Fat Grafting NCT02494752 | King Edward Medical University | N/A |
| Terminated | Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference NCT02492997 | Venus Concept | N/A |
| Completed | Factors Mediating Gut Microbiota Dysbiosis and Metabolic Disease in HIV Patients. NCT02258685 | University of Colorado, Denver | — |
| Active Not Recruiting | Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy NCT02262806 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Active Not Recruiting | Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy NCT02262832 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers NCT02647853 | Topokine Therapeutics, Inc. | Phase 1 |
| Completed | Lipodystrophy Connect Patient Registry NCT02577952 | PatientCrossroads | — |
| Completed | Identification of a New Gene Involved in Hereditary Lipodystrophy NCT02056912 | University Hospital, Bordeaux | N/A |
| Completed | Short-term Effects of Leptin in People With Lipodystrophy NCT01778556 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Quality of Life, Sleep, and Biomarkers in People With HIV/AIDS NCT03445351 | JULIANY DE SOUZA ARAUJO | N/A |
| Completed | Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steato NCT01679197 | University of Michigan | Phase 2 |
| Withdrawn | Egrifta Replacement and Sleep Disordered Breathing NCT01788462 | Johns Hopkins University | — |
| Completed | Metabolic Abnormalities in HIV-infected Persons NCT01612858 | Tufts Medical Center | Phase 4 |
| Completed | Adipocyte, Insulin-resistance and Immunity : Evaluation of Interleukin-7 in Lipodystrophy, Diabetes and Obesit NCT01784289 | University Hospital, Lille | — |
| Unknown | Exercise for Patients With HIV Infections NCT00910936 | Charite University, Berlin, Germany | Phase 2 / Phase 3 |
| Completed | An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertri NCT00677313 | Bristol-Myers Squibb | N/A |
| Completed | Lopinavir/r Monotherapy Versus Abacavir/Lamivudine and Lopinavir/r for Limb Fat Recovery in Persons With Lipoa NCT00865007 | Fundacion SEIMC-GESIDA | Phase 4 |
| Completed | Raltegravir Therapy for Women With HIV and Fat Accumulation NCT00656175 | University of California, Los Angeles | Phase 2 |
| Unknown | Autologous Adipose-Derived Stem Cell Transplantation in Patients With Lipodystrophy NCT00715546 | Irmandade Santa Casa de Misericórdia de Porto Alegre | Phase 1 |
| Completed | TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy NCT00608023 | Theratechnologies | Phase 3 |
| Completed | Corticosteroid-induced Lipodystrophy and Adipokines NCT00822042 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | SHARE: Simple HAART With Abacavir, Reyataz, and Epivir NCT00426296 | Clinical Alliance for Research & Education - Infectious Diseases, LLC. | Phase 4 |
| Completed | TH9507 in Patients With HIV-Associated Lipodystrophy NCT00123253 | Theratechnologies | Phase 3 |
| Completed | Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adult NCT00119379 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 2 |
| Completed | Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRT NCT00119405 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients NCT00119769 | Hvidovre University Hospital | Phase 4 |
| Unknown | White Light Scanning to Aid Body Contouring: A Pilot Project NCT01093950 | Eastern Virginia Medical School | — |
| Completed | Exercise and Pioglitazone for HIV-Metabolic Syndromes NCT00639457 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | N/A |
| Completed | Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Com NCT00192621 | Kirby Institute | Phase 4 |
| Completed | Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients NCT00082628 | EMD Serono | Phase 3 |
| Unknown | Proton Magnetic Resonance Spectroscopy (1H MRS) in Evaluating the Bone Marrow, Muscle and Adipose Tissue on No NCT00172315 | National Taiwan University Hospital | — |
| Completed | A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth NCT00069004 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | Study to Evaluate Changes in Limb Fat When Switching From a Thymidine Analogue NCT00647946 | Gilead Sciences | Phase 2 |
| Completed | Therapeutic Approaches to HAART-Induced Lipodystrophy NCT00461552 | University of Texas Southwestern Medical Center | Phase 2 |
| Completed | Lactate Metabolism Study in HIV Infected Persons NCT00202228 | Queen's University | Phase 4 |
| Completed | Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients NCT00028314 | National Institute of Allergy and Infectious Diseases (NIAID) | N/A |
| Completed | Leptin to Treat Lipodystrophy NCT00025883 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Pravastatin for Hyperlipidaemia in HIV. NCT00227500 | Kirby Institute | Phase 4 |
| Completed | A Study to Determine How and Why HIV-Infected Subjects on Anti-viral Treatment Develop Lipodystrophy NCT00006190 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 4 |
| Completed | The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children NCT00006064 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | Leptin to Treat Lipodystrophy NCT00005905 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Unknown | Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected Adults NCT00331448 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | A Study of Increased Lactic Acid and Abnormal Fat Distribution in HIV-Positive Patients NCT00005764 | Glaxo Wellcome | Phase 4 |
| Completed | Study of Alpha-2 Adrenergic Receptor Dysfunction in Regional Lipoatrophy NCT00004329 | National Center for Research Resources (NCRR) | — |
| Completed | Metabolism and Body Shape of Healthy Children and Children With Chronic Infections NCT00001142 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Completed | Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome NCT00006185 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 1 |
| Completed | The Effects of Anabolic Steroids and Protease Inhibitors on People Living With HIV/AIDS NCT00202241 | Queen's University | N/A |
| Completed | Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalit NCT00015691 | National Institute of Allergy and Infectious Diseases (NIAID) | N/A |
| Available | Expanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin Signaling NCT04710056 | Regeneron Pharmaceuticals | — |
| Completed | Changing to Nonprotease Inhibitor Treatment to Improve Side Effects NCT00021463 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 2 |
| Completed | Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids NCT00006412 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 3 |
| Completed | Perceived Changes in Body Build and Image in Patients Who Are Now Taking or Recently Have Stopped Taking Anti- NCT00006290 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs NCT00017758 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Withdrawn | Clinical Trial to Determine the Efficacy of Sculptra™ Dermal Filler for the Correction of Contour Deformities NCT00360139 | Dermatology Cosmetic Laser Medical Associates of La Jolla, Inc. | Phase 4 |