| Not Yet Recruiting | Effect of Virtual Reality on Patient Outcomes and Satisfaction in Total Knee Replacement NCT06933732 | Aykut Turgut | N/A |
| Withdrawn | Investigating the Effect of Dronabinol on Post-surgical Pain NCT04099355 | New York State Psychiatric Institute | EARLY_Phase 1 |
| Recruiting | Investigating Patient Satisfaction With Smart Knee Implants NCT06968143 | University of Chicago | N/A |
| Enrolling By Invitation | Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Pa NCT07362589 | Yeditepe University | N/A |
| Recruiting | The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery NCT07109557 | Niran Çoban | N/A |
| Recruiting | Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement NCT06768762 | University of South Carolina | N/A |
| Completed | Effectiveness of Peri-operative Combined Use of 2 Doses of Dexamethasone With Tranexamic Acid in Lower Limb Jo NCT06653699 | Indus Hospital and Health Network | N/A |
| Completed | Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide NCT06064318 | Rigshospitalet, Denmark | — |
| Completed | Trial of Liposomal Bupivacaine for TKA NCT05635916 | Northern Light Mercy Hospital | Phase 4 |
| Recruiting | The Medacta GMK SpheriKA Post-Marketing Surveillance Study NCT05459948 | Medacta International SA | — |
| Completed | CARINAE for Stress Relief in Perioperative Care NCT05184725 | Adhera Health, Inc. | N/A |
| Unknown | Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty NCT04314505 | Taipei Veterans General Hospital, Taiwan | Phase 4 |
| Unknown | Intelligent Operating Room (InOR) for Orthopaedic Surgery NCT04167787 | Digital Surgery Ltd. | — |
| Completed | Total Knee Replacement With Tourniquet or Aquamantys NCT04016285 | Stephen Duncan | N/A |
| Completed | Efficacy and Safety of Acupuncture Treatment as an Adjunctive Therapy After Knee Replacement NCT03633097 | Gachon University Gil Oriental Medical Hospital | N/A |
| Completed | Survey of Running Following a TKA NCT03848520 | Brigitte Jolles, MD | — |
| Unknown | Prediction of Outcomes Following Total Knee Replacement- Pilot NCT04328701 | Brigham and Women's Hospital | N/A |
| Completed | Physical Therapy Components for Maximum TKR Outcome NCT03120052 | University of Massachusetts, Worcester | — |
| Unknown | Retrospective Evaluation of Clinical and Functional Results and Survivorship of Total Knee Replacement and Tot NCT04199377 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | N/A |
| Unknown | Retrospective Clinical and Functional Evaluation of Patients Undergoing Knee Replacement With Small Implants NCT04198389 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | N/A |
| Completed | A Retrospective Study of the Navio Robotic-assisted Surgical System NCT03072459 | Smith & Nephew, Inc. | — |
| Unknown | Results of a Mobile Unicompartimental Knee Prosthesis NCT03130309 | University Hospital, Strasbourg, France | — |
| Unknown | Survival Rates of Patients With Mobile Bearing Total Knee Arthroplasty After 10 Years NCT02651571 | University Hospital, Strasbourg, France | — |
| Unknown | Study of an All Polyethylene Tibial Component NCT02540902 | Golden Jubilee National Hospital | N/A |
| Unknown | Biomechanical Assessment of a High Congruency Knee Bearing NCT02422251 | Golden Jubilee National Hospital | N/A |
| Completed | Transcranial Direct Current Stimulation for Postoperative Pain in Knee Arthroplasty NCT02704182 | Assiut University | N/A |
| Completed | Effects of Balance Exercises Circuit in Patients With Hip or Knee Arthroplasty NCT02920151 | Grupo de Estudos e Pesquisas Sobre Atividade Física Para Idosos | N/A |
| Completed | Comparison of Oxford UKA and Sigma UKA With RSA. NCT03434600 | Regional Hospital Holstebro | N/A |
| Unknown | C3 Total Joint Patient Registry NCT02188199 | DC2 Healthcare | — |
| Terminated | Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement NCT01743313 | Coxa, Hospital for Joint Replacement | — |
| Completed | A Trial of Mechanical Axis vs Kinematic Alignment in Total Knee Replacement NCT02527148 | Stryker South Pacific | N/A |
| Completed | Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement NCT01021826 | Coxa, Hospital for Joint Replacement | — |
| Completed | Disability and Self-rated Health Following Primary Knee Replacement NCT01236729 | Coxa, Hospital for Joint Replacement | — |
| Completed | ARIXTRA Local Study For Registration In China. NCT00328939 | GlaxoSmithKline | Phase 3 |