NCT06768762

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 336 (estimated)
• Sponsor: University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Detailed description

All participants will receive a 6-month, fully automated online behavioral exercise program (Energize! Exercise Program). This program is designed to increase moderate-intensity physical activity among individuals who engage in little to no physical activity at baseline. Over the course of the program, participants are given a physical activity goal which starts at 75 minutes per week and gradually progresses to 200 minutes per week. Participants are instructed to view a 10-15-minute video lesson weekly, during months 1-3, and monthly during months 4-6. These lessons teach behavioral principles for increasing exercise and maintaining physical activity long-term. Participants are also asked to complete an 'Apply Your Knowledge' activity after watching each video lesson. These activities are designed to help the participant engage more with the lesson content, with a particular emphasis on applying the content to their lives. Within this program, participants are also asked to plan and report their exercise each week, and automated feedback is provided based upon their weekly physical activity reports. In addition to receiving the Energize! Exercise Program, participants will be randomly assigned to receive 0-4 supplemental intervention components (phone coaching, progress reports to providers, 'Hear From Others' videos, and individualized feedback) which are each described in more detail below.

Conditions

• Knee Replacement

Interventions

Type	Name	Description
BEHAVIORAL	Phone Coaching	Participants will receive 11 coaching calls with a health coach. Calls will occur weekly during the first month, twice/month during months 2-3, and once/month during months 4-6. Each call is expected to last 10-15 minutes.
BEHAVIORAL	Progress reports to providers	Progress reports on physical activity and program adherence will be sent to participants providers at 3 and 6 months.
BEHAVIORAL	'Hear from Others' Videos	Participants will receive monthly 'Hear From Others' videos. The videos will include other adults with knee replacement discussing the challenges they have faced and strategies to overcome barriers to activity.
BEHAVIORAL	Individualized Feedback	Participants will receive individualized feedback from a coach via email. The feedback will specifically focus on participant responses to the 'Apply Your Knowledge' activities and will correspond with the video lessons. Feedback will be weekly during months 1-3 and monthly during months 4-6.
BEHAVIORAL	Online exercise program	MOST Energized! Online Exercise Program

Timeline

• Start date: 2025-01-21
• Primary completion: 2028-12-30
• Completion: 2029-07-31
• First posted: 2025-01-10
• Last updated: 2025-03-07

Locations

1 site across 1 country: United States