Trials / Conditions / Homozygous Familial Hypercholesterolemia (HoFH)

Homozygous Familial Hypercholesterolemia (HoFH)

12 registered clinical trials studyying Homozygous Familial Hypercholesterolemia (HoFH) — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administrat NCT07447648	Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)	—
Recruiting	The ORIGIN-FH Study NCT07470723	University of Wisconsin, Madison	N/A
Recruiting	A Dose-exploration Study of EDP167 in HoFH NCT07489209	Eddingpharm (Zhuhai) Co., Ltd.	Phase 2
Not Yet Recruiting	A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients NCT06712771	Visirna Therapeutics HK Limited	Phase 3
Active Not Recruiting	Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients Wit NCT06832371	Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)	—
Recruiting	A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias NCT07491172	CRISPR Therapeutics AG	Phase 1
Completed	Identifying and Genotyping Homozygous Familial Hypercholesterolemia (HoFH) Patients NCT04148001	REGENXBIO Inc.	—
Unknown	A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501 NCT04080050	REGENXBIO Inc.	—
Completed	Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholeste NCT03403374	Amgen	Phase 4
Terminated	A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH) NCT02651675	REGENXBIO Inc.	Phase 1 / Phase 2
Completed	A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hyperchole NCT02434497	AstraZeneca	Phase 3
Completed	A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Famili NCT02226198	AstraZeneca	Phase 3