Trials / Recruiting
RecruitingNCT07470723
The ORIGIN-FH Study
Opportunity to Reach Individuals With Genetic Dyslipidemia During Infancy and the Newborn Period to Find Familial Hypercholesterolemia
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- Sponsor
- University of Wisconsin, Madison · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this clinical trial is to identify different types of Familial Hypercholesterolemia (FH) in infants and newborns. Participants will: * undergo a cheek swab for genetic testing (parents only) * have 5 blood samples collected Participants can expect to be in the trial for 2 years.
Detailed description
ORIGIN-FH is a two-phase cohort study that will identify and enroll expectant parents where one or both partners has phenotypic and/or genotypic familial hypercholesterolemia in order to prospectively screen and diagnose their newborns with HoFH, HeFH, or are unaffected by FH.
Conditions
- Heterozygous Familial Hypercholesterolemia (HeFH)
- Homozygous Familial Hypercholesterolemia (HoFH)
- Familial Hypercholesterolemia
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Screening for FH | Participants will provide 5 blood samples for screening for FH. |
Timeline
- Start date
- 2026-02-14
- Primary completion
- 2029-02-14
- Completion
- 2029-02-14
- First posted
- 2026-03-13
- Last updated
- 2026-03-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07470723. Inclusion in this directory is not an endorsement.