| Recruiting | Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-speci NCT07148050 | Seattle Children's Hospital | Phase 1 |
| Recruiting | Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells NCT06198296 | Baylor College of Medicine | Phase 1 |
| Recruiting | Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepat NCT07188311 | Sun Yat-sen University | N/A |
| Active Not Recruiting | A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer NCT06521567 | GlaxoSmithKline | Phase 1 / Phase 2 |
| Not Yet Recruiting | Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models NCT06822842 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Recruiting | Agnostic Therapy in Rare Solid Tumors NCT06638931 | Instituto do Cancer do Estado de São Paulo | Phase 2 |
| Recruiting | A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers NCT06541652 | Federation Francophone de Cancerologie Digestive | — |
| Completed | Evaluation of Lung Metastases Based on Ultrashort Echo Time MRI NCT05763173 | RenJi Hospital | — |
| Unknown | GastroIntestinal Cancer in Children and Adolescents NCT05693519 | Paul G. Kemps, MD | — |
| Recruiting | ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma NCT04634357 | Eureka Therapeutics Inc. | Phase 1 / Phase 2 |
| Recruiting | B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3 NCT04897321 | St. Jude Children's Research Hospital | Phase 1 |
| Unknown | Sequential PD-1/PD-L1 Inhibitor and LENvatinib in TLCT and Refractory Hepatoblastoma After Chemotherapy NCT05322187 | RenJi Hospital | Phase 2 / Phase 3 |
| Completed | Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families NCT05245123 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors NCT05302921 | Children's National Research Institute | Phase 2 |
| Recruiting | Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Sol NCT04337177 | Valent Technologies, LLC | Phase 1 |
| Completed | Diagnostic Efficacy and Prognostic Value of 18F-FDG PET/CT (MR) in Pediatric Solid Blastoma NCT06190574 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Recruiting | A Prospective Multicenter Clinical Study of SCCG Protocol and ctDNA 5hmc in Predicting the Chemotherapy Sensit NCT07300449 | Sun Yat-sen University | Phase 2 |
| Recruiting | A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHI NCT04478292 | Shanghai Children's Medical Center | Phase 3 |
| Terminated | Yttrium-90 (TARE-Y90) in Children, Adolescents, and Young Adults With Liver Tumors NCT04315883 | Nemours Children's Clinic | — |
| Unknown | Deep Learning Magnetic Resonance Imaging Radiomics for Diagnostic Value of Hepatic Tumors in Infants NCT05170282 | West China Hospital | — |
| Active Not Recruiting | B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults NCT04483778 | Seattle Children's Hospital | Phase 1 |
| Withdrawn | T Cells co- Expressing a Second Generation Glypican 3-specific Chimeric Antigen Receptor With Cytokines Interl NCT04093648 | Baylor College of Medicine | Phase 1 |
| Active Not Recruiting | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults NCT03618381 | Seattle Children's Hospital | Phase 1 |
| Completed | PIVKA-II Combined With Alpha-Fetoprotein for Diagnostic and Prognostic Value of Hepatic Tumors in Infants NCT03645655 | Shanghai Children's Medical Center | — |
| Active Not Recruiting | Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Canc NCT03533582 | Children's Oncology Group | Phase 3 |
| Completed | Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or H NCT03220035 | National Cancer Institute (NCI) | Phase 2 |
| Active Not Recruiting | Paediatric Hepatic International Tumour Trial NCT03017326 | University of Birmingham | Phase 3 |
| Active Not Recruiting | Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wi NCT02867592 | National Cancer Institute (NCI) | Phase 2 |
| Recruiting | Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies NCT04308330 | New York Medical College | Phase 1 |
| Unknown | G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tum NCT02933333 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Phase 4 |
| Unknown | Combined Modality Therapy in Hepatoblastoma: South Egypt Cancer Institute Experience NCT02557750 | Assiut University | — |
| Recruiting | Molecular Basis of Pediatric Liver Cancer NCT03959800 | University of Pittsburgh | — |
| Completed | Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors NCT02390843 | Emory University | Phase 1 |
| Withdrawn | Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors NCT02011126 | Children's Oncology Group | Phase 2 |
| Completed | Auto Transplant for High Risk or Relapsed Solid or CNS Tumors NCT01505569 | Masonic Cancer Center, University of Minnesota | N/A |
| Completed | Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors NCT01331135 | Emory University | Phase 1 |
| Completed | Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia NCT01154816 | Children's Oncology Group | Phase 2 |
| Completed | A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminar NCT01125800 | Novartis Pharmaceuticals | Phase 1 / Phase 2 |
| Withdrawn | Hepatoblastoma Biology Study and Tissue Bank NCT00228683 | Emory University | N/A |
| Unknown | Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors NCT00179816 | Ann & Robert H Lurie Children's Hospital of Chicago | Phase 1 / Phase 2 |