| Recruiting | Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy NCT06483061 | University of Alberta | Phase 2 |
| Recruiting | A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy NCT06422923 | Neurona Therapeutics | Phase 1 / Phase 2 |
| Not Yet Recruiting | Innovative MRI to Localize the Epileptic Zone NCT06057233 | University Hospital, Grenoble | — |
| Recruiting | A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients Wi NCT06492720 | NaviFUS Corporation | N/A |
| Recruiting | Evaluation of the NaviFUS System in Drug Resistant Epilepsy NCT05947656 | Genovate-NaviFUS (Australia) Pty Ltd. | N/A |
| Unknown | A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score NCT06036732 | Istanbul University - Cerrahpasa | — |
| Recruiting | Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resi NCT05339438 | Central Hospital, Nancy, France | N/A |
| Unknown | Self-modulation of the Sense of Agency by Means of Real-time Neurofeedback NCT05214833 | ETH Zurich | N/A |
| Completed | Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy NCT04897776 | Yale University | N/A |
| Recruiting | Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus NCT04717388 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Structural Cartography of the Insula in Temporal Epilepsy Patients NCT04871555 | Central Hospital, Nancy, France | — |
| Recruiting | Localizing Epileptic Networks Using MRI and iEEG NCT04649008 | University of Pennsylvania | EARLY_Phase 1 |
| Unknown | Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy NCT04164056 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 4 |
| Completed | Epilepsy Surgery and Cognitive Outcome NCT04264780 | Oslo University Hospital | — |
| Completed | SEEG Guided RF-TC v.s. ATL for mTLE With HS NCT03941613 | Xuanwu Hospital, Beijing | N/A |
| Unknown | Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy NCT03871842 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging NCT04169581 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Recruiting | Investigating Epilepsy: Screening and Evaluation NCT03478852 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Brain Network Activation Analysis in Epilepsy NCT03265925 | ElMindA Ltd | — |
| Withdrawn | The Utility of NIOM During LITT for Refractory MTLE NCT02913742 | Duke University | N/A |
| Unknown | EASINESS-TRIAL - Enhancing Safety in Epilepsy Surgery NCT04952298 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Treating Deep Seizure Foci With Noninvasive Surface Brain Stimulation NCT02339376 | Beth Israel Deaconess Medical Center | N/A |
| Completed | CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patien NCT02262156 | El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez | N/A |
| Enrolling By Invitation | Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe Epilepsy NCT02151175 | BrainSonix Inc. | N/A |
| Recruiting | Surgery as a Treatment for Medically Intractable Epilepsy NCT01273129 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Terminated | PRX-00023 Therapy in Localization-Related Epilepsy NCT01281956 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Completed | GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression NCT00931619 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Language Mapping in Patients With Epilepsy NCT00706160 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Light Scattering Spectroscopy to Determine Brain Tumors NCT00067418 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Early Surgical Intervention to Treat Epilepsy NCT00040326 | University of California, Los Angeles | Phase 3 |
| Completed | Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy NCT00001672 | National Institute of Neurological Disorders and Stroke (NINDS) | — |