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Not Yet RecruitingNCT06057233

Innovative MRI to Localize the Epileptic Zone

Quantitative MRI and GABA Spectroscopy to Localize the Epileptic Zone

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
40 (estimated)
Sponsor
University Hospital, Grenoble · Academic / Other
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The goal of EPI-CATCHER is to outline the clinical potential of multiparametric quantitative MRI (mqMRI) and of GABA-edited magnetic resonance spectroscopy (GABA-MRS), combined with machine learning tools, as imaging biomarkers to localize and delineate the EZ.

Detailed description

After informed consent, patient candidate to resection surgery will undergo two extra MRI sessions before surgery: one for multiparametric quantitative MRI (mqMRI) and one for GABA-edited magnetic resonance spectroscopy (GABA-MRS) In parallel, a group of healthy volunteers will also undergo the two MRI sessions described above, to collect reference data.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTmqMRI and GABA-MRSmultiparametric quantitative MRI (mqMRI) and of GABA-edited magnetic resonance spectroscopy (GABA-MRS)

Timeline

Start date
2024-10-01
Primary completion
2028-11-01
Completion
2028-11-01
First posted
2023-09-28
Last updated
2024-08-23

Source: ClinicalTrials.gov record NCT06057233. Inclusion in this directory is not an endorsement.

Innovative MRI to Localize the Epileptic Zone (NCT06057233) · Clinical Trials Directory