| Not Yet Recruiting | The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients NCT05279937 | Tulane University | Phase 3 |
| Not Yet Recruiting | Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients NCT06336473 | GCS Ramsay Santé pour l'Enseignement et la Recherche | N/A |
| Enrolling By Invitation | Group Coaching Study for Life Goals NCT07083713 | Thomas Jefferson University | N/A |
| Recruiting | FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases NCT06539169 | xCures | — |
| Unknown | RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders NCT06325345 | University Health Network, Toronto | N/A |
| Active Not Recruiting | Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes NCT05389865 | Golden Jubilee National Hospital | — |
| Completed | Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation NCT06105541 | Medical University of South Carolina | N/A |
| Recruiting | Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research NCT04806620 | Brain Inflammation Collaborative | — |
| Active Not Recruiting | Analysis of Muscular Properties in Patients With MFS and EDS NCT05720923 | IRCCS Policlinico S. Donato | — |
| Recruiting | Light Exposure on Pain in Hypermobile Ehlers-Danlos Syndrome NCT05561270 | New York Institute of Technology | N/A |
| Active Not Recruiting | Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers NCT05603741 | University of Calgary | Phase 4 |
| Unknown | Characterization of Bleeding Disorders in EDS NCT05434728 | University Health Network, Toronto | — |
| Unknown | Ultrastructural Collagen Markers in Ehlers Danlos Syndromes NCT05429996 | University Health Network, Toronto | — |
| Unknown | Vision-based Assessment of Joint Extensibility in Ehlers Danlos Syndrome NCT05366114 | University Health Network, Toronto | — |
| Unknown | Impact of Oxygen Therapy on Fatigue in Patients With Hypermobile-type Ehlers-Danlos Syndrome NCT04890431 | Hospital St. Joseph, Marseille, France | Phase 4 |
| Completed | Safety and Performance of POLYTHESE® Vascular Prosthesis NCT05516043 | Perouse Medical | — |
| Completed | Evaluation of a Cohort of Patients With Ehlers-Danlos Syndrome Treated With Orthopedic Surgery (SED-eval) NCT05137379 | Ramsay Générale de Santé | — |
| Completed | Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS) NCT04734041 | National University of Natural Medicine | N/A |
| Completed | Effects of a Multidisciplinary Outpatient Rehabilitation Program in Patients With Ehlers-Danlos Syndrome. NCT04680793 | Hakimi Adrien | N/A |
| Active Not Recruiting | Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers NCT04036305 | Vanderbilt University Medical Center | — |
| Completed | Evaluation of the Effect of Custom Compression Garments on Standing Static Balance in Ehlers Danlos Syndrome NCT03986229 | University Hospital, Toulouse | N/A |
| Unknown | Study of Arterial Properties by Ultra-high Frequency Ultrasound in Fibromuscular Dysplasia and Vascular Ehlers NCT03596437 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Gait Retraining in Patients With Joint Hypermobility Syndrome/Hypermobile Ehlers Danlos Syndrome NCT03575182 | University of South Florida | N/A |
| Completed | Opioid-Free Anesthesia for Patients With Joint Hypermobility Syndrome Undergoing Craneo-Cervical Fixation: A C NCT04437589 | Servei Central d'Anestesiologia | — |
| Completed | Standing Cognition and Co-morbidities of POTS Evaluation NCT03602482 | Milton S. Hershey Medical Center | N/A |
| Unknown | Efficiency Clinical Study of NOVATEX MEDICAL Compression Garments in Patients With Ehlers-Danlos Syndrome NCT03330977 | Novatex Medical | N/A |
| Completed | Genetics of Ehlers-Danlos Syndrome NCT03093493 | Boston University | — |
| Unknown | Origins and Impact of EDS in Connective Tissues and Skin NCT02721797 | University College, London | — |
| Completed | Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies NCT03681080 | RWTH Aachen University | N/A |
| Completed | Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan NCT02985710 | Massachusetts General Hospital | N/A |
| Completed | Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome NCT02435745 | University of Zurich | — |
| Recruiting | Registry of Ehlers-Danlos Syndrome NCT04133272 | Luca Sangiorgi | — |
| Recruiting | Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices NCT02050113 | Andres Schanzer | N/A |
| Completed | Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life NCT01367977 | Genetic Disease Investigators | — |
| Completed | Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI NCT01356134 | Genetic Disease Investigators | — |
| Completed | National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions NCT01322165 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Studies of Heritable Disorders of Connective Tissue NCT00270686 | National Institute on Aging (NIA) | — |
| Completed | Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome NCT00001966 | National Human Genome Research Institute (NHGRI) | Phase 2 |
| Completed | Study of Heritable Connective Tissue Disorders NCT00001641 | National Human Genome Research Institute (NHGRI) | — |