| Not Yet Recruiting | Vaginal Sildenafil for Primary Dysmenorrhea NCT07508358 | Kevin Hellman | Phase 1 |
| Not Yet Recruiting | Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents NCT07457957 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea NCT06398990 | Acibadem University | N/A |
| Not Yet Recruiting | The Effect of Sensory Awareness Training Given to Women of Reproductive Age on Dysmenorrhea and Kinesiophobia NCT07097285 | Saglik Bilimleri Universitesi | N/A |
| Not Yet Recruiting | The Good Pain Consultation in Endometriosis. NCT07205614 | Sorlandet Hospital HF | N/A |
| Not Yet Recruiting | Menstrual Pain Intervention Among Students NCT07155291 | University of Potsdam | N/A |
| Recruiting | A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pa NCT07209566 | Azusa Pacific University | N/A |
| Recruiting | IV Magnesium in the Treatment of Acute Dysmenorrhea NCT07248540 | Havva Betül Bacak | N/A |
| Completed | Effectiveness of Post Isometric Relaxation Technique Versus Simple Stretching Exercises for Pain and Physical NCT07052487 | Khyber Medical University Peshawar | N/A |
| Completed | Anastatica Hierochuntica Breathing Exercises Dysmenorrhea NCT07481552 | Çanakkale Onsekiz Mart University | N/A |
| Enrolling By Invitation | The Effect of Physical Activity Levels on Dysmenorrhea Severity, Menstrual Symptoms, and Functional and Emotio NCT07011875 | Karabuk University | — |
| Recruiting | NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL) NCT06861920 | Endeavor Health | Phase 4 |
| Active Not Recruiting | Effectiveness of ST With TENS and Stretching Exercises on Menstrual Pain and QOL With Dysmenorrhea. RCT NCT07036913 | Superior University | N/A |
| Completed | Effectiveness of Pilates Exercises in the Treatment of Dysmenorrhea: A Randomized Controlled Trial NCT06774521 | Uskudar University | N/A |
| Active Not Recruiting | Music and Puzzle Use in Dysmenorrhea Relief NCT07081789 | Burdur Mehmet Akif Ersoy University | N/A |
| Recruiting | Effect of TENS on Pain and Symptoms in Primary Dysmenorrhea NCT06741059 | Osmaniye Korkut Ata University | N/A |
| Not Yet Recruiting | Effect of Bioptron on Primary Dysmenorrhea NCT06729749 | Cairo University | N/A |
| Enrolling By Invitation | Core Stability vs. Traditional Physical Therapy: A Comparative Study on Alleviating Low Back Pain in Dysmenorr NCT06807229 | Delta University for Science and Technology | N/A |
| Completed | A Single Group Study to Evaluate the Effects of a Topical Product on Cramps Associated With the Menstrual Cycl NCT06939972 | Rael | N/A |
| Recruiting | The Effect of Distraction Techniques Used in Intramuscular (IM) Injections on Pain in Adolescents Presenting t NCT06842329 | Duygu MEZDE | N/A |
| Completed | Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea NCT06673537 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | Doppler Ultrasound-Guided Angiopuncture for Dysmenorrhea Pain: A Clinical Trial NCT07176910 | City University of Hong Kong | N/A |
| Recruiting | Effect of Pelvic Floor-Based Training on Dysmenorrhea NCT06600230 | Uskudar University | N/A |
| Recruiting | Electroacupuncture for Dysmenorrhea Secondary to Adenomyosis NCT06364592 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | N/A |
| Withdrawn | Chinese Herbal Medicine for Gynecologic Patients NCT06187376 | Icahn School of Medicine at Mount Sinai | Phase 2 |
| Recruiting | Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort Study NCT06353789 | University of Oxford | — |
| Active Not Recruiting | Cryotherapy in Nulliparous Women with Dysmenorrhea NCT06667440 | University of Malaga | N/A |
| Completed | Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenor NCT05900336 | Mclean Hospital | Phase 4 |
| Active Not Recruiting | The Impact of Oral Probiotics on Improving the Quality of Life in Patients With Dysmenorrhea. NCT07530081 | Glac Biotech Co., Ltd | N/A |
| Completed | The Effect of Su Jok on Dysmenorrhea NCT06896851 | Ankara Medipol University | N/A |
| Unknown | Effects of Breathing Exercises on Women With Primary Dysmenorhea NCT06321224 | Ankara Yildirim Beyazıt University | N/A |
| Completed | Examining the Impact of Aerobic and Core Exercises on Primary Dysmenorrhea in High School Females NCT06394726 | Istanbul Bilgi University | N/A |
| Unknown | The Effect of Mindfulness Practice on Coping With Primary Dysmenorrhea on Pain and Anxiety Level NCT06293313 | Inonu University | N/A |
| Unknown | Pilot Study to Investigate the Effect of a Dysmenorrhoea App NCT06283225 | Endo Health GmbH | N/A |
| Completed | Core Muscle Strength in Women with Primary Dysmenorrhoea NCT06854900 | Derya Azim | — |
| Unknown | Brain Structural and Functional Connectivity Changes in the Period of Dysmenorrhea: a Prospective fMRI Study NCT06178406 | Women's Hospital School Of Medicine Zhejiang University | — |
| Unknown | Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea NCT06294743 | Taichung Armed Forces General Hospital | EARLY_Phase 1 |
| Completed | The Effect of Reiki on Pain, Stress and Comfort Level in Students Experiencing Dysmenorrhea NCT06075784 | Ondokuz Mayıs University | N/A |
| Completed | Effect of Shockwave Therapy on Low Back Pain in Primary Dysmenorrhea NCT06762106 | Deraya University | N/A |
| Completed | MOPEXE and RE in Treating Dysmenorrhea NCT06011928 | Uskudar University | N/A |
| Completed | Listening Music, Drawing on Coping With Dysmenorrhea Complaints of Nursing Students NCT06027489 | Trakya University | N/A |
| Completed | Improving Menstrual Health Through BCC Among Bangladeshi University Students NCT07047222 | Shahjalal University of Science and Technology | N/A |
| Active Not Recruiting | Menstrual Complaints in Adolescents and Adults NCT06921629 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Effect of Myofascial Release on Scoliotic Females With Dysmenorrhea. NCT05817513 | Cairo University | N/A |
| Completed | Translation, Reliability, and Validity of Turkish Version of the Working Ability, Location, Intensity, Days of NCT05829512 | Tokat Gaziosmanpasa University | — |
| Unknown | The Study on the Therapeutic Effect and Mechanism of Transcutaneous Acupoint Electrical Stimulation in Female NCT05799924 | Honglan Zhu | N/A |
| Unknown | Effect of Lavender Inhalation on Dysmenorrhea NCT05995730 | Saglik Bilimleri Universitesi | N/A |
| Unknown | Research and Development of WPAPS Based on the Modern Technology of Traditional Chinese Medicine NCT05815654 | Hong Kong Baptist University | N/A |
| Unknown | Symptoms and Quality of Life of Patients With Suspected Endometriosis NCT05624567 | Medical University of Vienna | — |
| Completed | The Effect of Psychoeducation on Dysmenorrhea in Nursing Students NCT05646238 | Gazi University | N/A |
| Completed | Yoga and Aerobic Exercise Training in Primary Dysmenorrhea NCT05623085 | Hacettepe University | N/A |
| Unknown | Effect of Integrated Neuromuscular Inhibition Technique in Females With Menstrual Low Back Pain NCT05461846 | Cairo University | N/A |
| Completed | Dysmenorrhea Exploration in Teenagers, Their Parents and Caregivers NCT05414825 | University Hospital, Toulouse | — |
| Completed | Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 NCT06227676 | Cornell University | Phase 2 / Phase 3 |
| Unknown | Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therap NCT05770297 | Indonesia University | N/A |
| Withdrawn | Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study NCT05227456 | Saskatchewan Health Authority - Regina Area | Phase 2 |
| Completed | Effects of Kinesiotaping With and Without Pelvic Tilts in Dysmenorrhea NCT05355194 | Riphah International University | N/A |
| Completed | Evaluation of Yoga and Conventional Physical Exercise for Pain and Quality of Life in Women With Endometriosis NCT07424859 | Beneficência Portuguesa de São Paulo | N/A |
| Unknown | The Effects of Exercise and Probiotics on Dysmenorrhea and Microbiome NCT05326217 | National Taipei University of Nursing and Health Sciences | N/A |
| Unknown | Honghuaruyi Wan for Endometriosis Dysmenorrhea NCT04942015 | Beijing University of Chinese Medicine | Phase 4 |
| Completed | Implementation of a Minor Ailment Service in Community Pharmacy Practice NCT05247333 | Universidad de Granada | N/A |
| Completed | Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From NCT04607382 | Bayer | — |
| Terminated | A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirm NCT04140175 | AbbVie | — |
| Completed | Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length NCT04425577 | Children's Mercy Hospital Kansas City | N/A |
| Completed | Kinesiotaping Versus Pilate Exercises NCT04359381 | Cairo University | N/A |
| Unknown | Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea NCT04091789 | Pure Green | Phase 2 |
| Unknown | The Efficacy of Two Types of Acupuncture on Autonomic Nervous Activity and Quality of Life in Women With Dysme NCT04178226 | Taipei City Hospital | N/A |
| Completed | TENS for Primary Dysmenorrhea NCT07521553 | Centro Universitario La Salle | N/A |
| Completed | Effect of Melatonin on Reduction of Pelvic Pain NCT03782740 | Karolinska Institutet | Phase 2 |
| Completed | Heat Application on Depression, Anxiety, Menstrual Attitude and Dysmenorrhea NCT04572555 | Balikesir University | N/A |
| Completed | Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy NCT03972917 | University of Campania Luigi Vanvitelli | — |
| Unknown | Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea NCT03697746 | Pamukkale University | N/A |
| Unknown | Iyengar Yoga Therapy for Dysmenorrhea and Endometriosis NCT03784976 | University of Illinois at Urbana-Champaign | N/A |
| Unknown | The Efficacy of Different Doses of Acupuncture in Dysmenorrhea NCT03881319 | Taipei City Hospital | N/A |
| Completed | Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain NCT03697720 | Endeavor Health | Phase 4 |
| Completed | Intravenous Tramadol Versus Intravenous Paracetamol in Patients With Dysmenorrhea NCT03509740 | Cairo University | Phase 4 |
| Completed | A Study to Assess Menstrual Cramp Pain Associated With Primary Dysmenorrhea NCT03448536 | Bayer | Phase 4 |
| Withdrawn | Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis NCT03325868 | Vanderbilt University Medical Center | Phase 4 |
| Unknown | Pulsed Electromagnetic Field Treatment for Painful Periods NCT03394547 | Birmingham Women's NHS Foundation Trust | N/A |
| Unknown | Cooperative Adenomyosis Network NCT03230994 | Peking Union Medical College Hospital | — |
| Completed | The Effectiveness and Safety of LIVIA® Transcutaneous Electrical Nerve Stimulation (TENS) in Women Suffering F NCT03064945 | iPulse Medical Ltd. (Livia) | Phase 2 |
| Terminated | Efficacy of Manual Therapy to Improve Quality of Life and Decrease Pain in Subjects With Endometriosis NCT03118154 | Clear Passage Therapies, Inc | — |
| Completed | Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N i NCT02910167 | Boehringer Ingelheim | — |
| Terminated | Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in the Treatment of Women With Pri NCT02668822 | Organon and Co | Phase 3 |
| Unknown | The Effect of Kinesio Taping Application for Dysmenorrhea NCT02663050 | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi | N/A |
| Completed | Electromagnetic Field Versus Diclofenac Drugs on Primary Dysmenorrhea NCT03269591 | Cairo University | N/A |
| Completed | Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilater NCT03761862 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Completed | Neural Therapy Effect and Bilateral Tubal Ligation NCT03891537 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Withdrawn | To Investigate Efficacy of YAZ in the Treatment of Dysmenorrhea NCT02617537 | Bayer | Phase 3 |
| Unknown | Menorrhagia, Dysmenorrhea and Iron Deficiency Among Young Women Soldiers and Effect on Activity NCT02685501 | Hadassah Medical Organization | — |
| Completed | Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrhea NCT02362711 | Nobelpharma | Phase 3 |
| Completed | The Efficacy of Viburnum Opulus 3X in the Treatment of Primary Dysmenorrhea NCT02467543 | University of Johannesburg | Phase 2 |
| Completed | The Effect of Connective Tissue Massage in Women With Primary Dysmenorrhoea NCT02372123 | Hacettepe University | N/A |
| Unknown | IV Paracetamol Versus IV Dexketoprofen in Dysmenorrhea NCT02373514 | Akdeniz University | Phase 4 |
| Completed | Chronic Pain Risk Associated With Menstrual Period Pain NCT02214550 | Endeavor Health | Phase 4 |
| Terminated | Norwegian Adenomyosis Study III: Peristalsis NCT02197936 | Oslo University Hospital | — |
| Completed | Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrhea NCT02255045 | Laboratorios Andromaco S.A. | Phase 2 / Phase 3 |
| Unknown | Continuous Versus Cyclic Oral Contraceptives for Endometriosis NCT02237131 | University of Athens | Phase 4 |
| Completed | Pulse Diagnoses in Patients While Dysmenorrhea is Attacking NCT03187782 | Taipei Hospital, Taiwan | — |
| Unknown | Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis NCT02031523 | Jiangsu Kanion Pharmaceutical Co., Ltd | Phase 4 |
| Completed | Comparative Study of BAY86-5300 With a Flexible Extended Regimen for Dysmenorrhea NCT01892904 | Bayer | Phase 3 |
| Completed | A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342 NCT01670656 | Organon and Co | Phase 2 |
| Active Not Recruiting | The Women's Health Study: From Adolescence to Adulthood NCT01738204 | Boston Children's Hospital | — |
| Unknown | A Randomized, Sham Device Controlled, Single Blinded Trial of Portable Transcutaneous Electrical Nerve Stimula NCT01662934 | Seoul National University Hospital | Phase 3 |
| Completed | AMPED Outcomes Registry of Post-ED Pain Management NCT01626235 | Radnor Registry Research, Inc | — |
| Completed | Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-06 NCT01462370 | Organon and Co | Phase 3 |
| Completed | Effectiveness of Nanoone Woman Underwear Using in the Management of Dysmenorrhea NCT01449305 | Chen Yi Enterprise, Co., Ltd. | N/A |
| Completed | YAZ Post-marketing Surveillance in Japan NCT01375998 | Bayer | — |
| Unknown | Long Term Outcomes Following Total Laparoscopic Hysterectomy and Laparoscopic Supracervical Hysterectomy NCT01289314 | Oslo University Hospital | N/A |
| Completed | Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea NCT01250587 | PDC Biotech GmbH | Phase 1 |
| Completed | A Feasibility Study Designed to Assess the Efficacy of the ActiLady Device in Adult Female Subjects With Dysme NCT00855829 | Hadassah Medical Organization | Phase 1 |
| Completed | Randomized Controlled Trial of Acupuncture for Dysmenorrhea NCT01116453 | National Taiwan University Hospital | Phase 3 |
| Completed | Efficacy and Safety Study of NPC-01 to Treat Dysmenorrhea NCT01129102 | Nobelpharma | Phase 3 |
| Unknown | Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation NCT01103518 | Fundação Educacional Serra dos Órgãos | Phase 4 |
| Completed | A Pilot Study of Acupoint Injection for Primary Dysmenorrhea NCT00995917 | University of California, San Francisco | N/A |
| Completed | Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With Endometriosis NCT00902746 | Nobelpharma | Phase 3 |
| Completed | VA111913 TS: First in Human Study NCT00769964 | Vantia Ltd | Phase 1 |
| Completed | Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary Dysmenorrhea NCT00746096 | Nobelpharma | Phase 3 |
| Completed | Prevalence of Menstrual Cycle Related Pain Complains in Adolescents and Young Adults NCT00590811 | University Hospital, Gasthuisberg | — |
| Completed | Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea NCT00517556 | Milton S. Hershey Medical Center | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods) NCT00651313 | Juniper Pharmaceuticals, Inc. | Phase 2 |
| Completed | SH T00186 Phase II/ III Optimal Drospirenone (DRSP) Dose Finding and Placebo-controlled Comparative Study NCT00511797 | Bayer | Phase 2 / Phase 3 |
| Completed | Viagra in the Treatment of Primary Dysmenorrhea NCT00123162 | Milton S. Hershey Medical Center | Phase 1 / Phase 2 |
| Completed | The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic Endometrio NCT00455845 | Mahidol University | Phase 3 |
| Completed | Pertubation With Lignocaine in Endometriosis NCT01329796 | Isifer AB | Phase 2 |
| Completed | Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrhea NCT00461305 | Bayer | Phase 2 / Phase 3 |
| Completed | A Comparison Study of Pain Relief From Dysmenorrhea Between the Vipon Tampon and Ibuprofen NCT00951561 | Another Way Products | N/A |
| Completed | Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in NCT00318500 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 2 |
| Terminated | Drotaverine in Dysmenorrhoea Treatment NCT00292747 | Sanofi | Phase 4 |
| Completed | A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain NCT00196313 | Duramed Research | Phase 2 |
| Completed | Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea. NCT00212277 | Nobelpharma | Phase 3 |
| Completed | A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain NCT00196365 | Duramed Research | Phase 3 |
| Completed | Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrhea NCT00212342 | Nobelpharma | Phase 3 |
| Completed | Vitamin K Injections for the Treatment of Painful Menstruation NCT00104546 | National Center for Complementary and Integrative Health (NCCIH) | Phase 1 |
| Unknown | Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist NCT00458458 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 3 |
| Completed | A Double Blind, Double Dummy, Randomized, Comparative Study Of The Efficacy And Safety Of Valdecoxib 40 Mg Twi NCT00649415 | Pfizer | Phase 4 |
| Completed | An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064) NCT00092729 | Organon and Co | Phase 3 |
| Completed | Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrhea NCT02183025 | Boehringer Ingelheim | Phase 2 |
| Completed | Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants NCT00011388 | National Institute of Environmental Health Sciences (NIEHS) | — |
| Withdrawn | Continuous Use of the Contraceptive Patch and the Personal Economic Impact. NCT00357981 | University of California, San Francisco | N/A |
| Completed | Effectiveness of the Transcutaneous Electrical Nerve Stimulation in Dysmenorrhea NCT01455285 | Universidade Federal do Piauí | N/A |