NCT02237131

Continuous Versus Cyclic Oral Contraceptives for Endometriosis

Continuous Versus Cyclic Use of Oral Contraceptives Following Surgery for Symptomatic Endometriosis

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: University of Athens · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the efficacy of oral contraceptives in a continuous fashion versus the usual cyclic fashion in the recurrence of endometriosis related symptoms and endometriomas following fertility-sparing surgery.

Detailed description

Oral contraceptives containing 0.03 mg ethinyl estradiol and 3mg drospirenone will be administered. One tablet a day for 21 days followed by 7 days pill free (cyclic fashion) or one tablet a day in a continuous fashion.

Conditions

• Dysmenorrhea
• Pelvic Pain
• Dyspareunia
• Endometrioma

Interventions

Type	Name	Description
DRUG	Oral contraceptives cyclic	tables containing Ethinyl estradiol 0.03mg and drospirenone 3mg will be administered in a cyclic fashion 21 days on 7 days off pill for 6 cycles.
DRUG	Oral contraceptives continuous	Patients will be treated with oral contraceptives containing 0.03mg ethinyl estradiol and 3 mg drospirenone per day in a continuous fashion.

Timeline

• Start date: 2014-04-01
• Primary completion: 2015-04-01
• Completion: 2015-12-01
• First posted: 2014-09-11
• Last updated: 2014-09-11

Locations

1 site across 1 country: Greece