| Not Yet Recruiting | HISMAR: Intraoperative Margin Assessment Using the Histolog® Scanner to Reduce Reoperation in Breast-Conservin NCT07527468 | Hôpital du Valais | N/A |
| Not Yet Recruiting | CAN1012 in Pre-Malignant DCIS and LCIS NCT07408856 | Providence Health & Services | Phase 1 |
| Not Yet Recruiting | Breast Tumour Size Measurement by Field Cycling Imaging NCT07492043 | University of Aberdeen | — |
| Withdrawn | Evaluation of Novel Iron-based Lymphatic Mapping Agent, Magtrace, for Delayed Sentinel Lymph Node Biopsy (SLNB NCT06868238 | University of Florida | Phase 2 |
| Recruiting | Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplast NCT06903468 | University of Florida | N/A |
| Recruiting | A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients. NCT07095114 | Barbara Ann Karmanos Cancer Institute | N/A |
| Recruiting | Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-S NCT06902311 | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
| Active Not Recruiting | Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion NCT06033092 | European Institute of Oncology | Phase 2 |
| Recruiting | DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as T NCT06075953 | QuantumLeap Healthcare Collaborative | Phase 2 |
| Recruiting | Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ NCT06218303 | Finn, Olivera, PhD | Phase 1 |
| Recruiting | Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer NCT06677944 | Yonsei University | Phase 2 |
| Completed | Demographics, Characteristics and Outcomes of Male Breast Cancer Patients at Methodist Health System NCT06133647 | Methodist Health System | — |
| Unknown | Excisional Vacuum-Assisted Breast Biopsy NCT05932758 | European Institute of Oncology | N/A |
| Recruiting | EXploring Inflammation and Social deTerminants Study in Breast Cancer Patients NCT07478016 | Thomas Jefferson University | — |
| Recruiting | Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT) NCT04985032 | RPCR, Inc. | — |
| Withdrawn | An Efficacy Study of the Xoft® Axxent® eBx® IORT System® "Lite" NCT04349111 | Xoft, Inc. | N/A |
| Recruiting | Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ NCT05218044 | Glendale Adventist Medical Center d/b/a Adventist Health Glendale | N/A |
| Completed | Acceptability of Active Monitoring (AM) as a Treatment Option for Ductal Carcinoma in Situ (DCIS) NCT03775213 | Duke University | N/A |
| Recruiting | Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ NCT04666961 | Institut Cancerologie de l'Ouest | Phase 2 |
| Withdrawn | Subzero and Scorpion Trial NCT05032079 | Larkin Community Hospital | N/A |
| Completed | Prospective Registry Trial for Single Port Robot-assisted Nipple Sparing Mastectomy (SPrNSM) NCT04866992 | University of Texas Southwestern Medical Center | — |
| Completed | The Ultrasound-guided Multiple-injection Costotransverse Block for Mastectomy and Primary Reconstructive Surge NCT04248179 | Zealand University Hospital | Phase 4 |
| Withdrawn | BrUOG 351: PRE-OPERATIVE APBI USING NIBB NCT03437915 | Jaroslaw Hepel | N/A |
| Completed | Living Well After Breast Surgery NCT03834532 | University of Texas at Austin | N/A |
| Withdrawn | Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors NCT02856503 | Eli Avisar, MD | Phase 1 / Phase 2 |
| Completed | Patient Outcomes from Second Film-readers and Test Threshold Relaxation in Breast Screening NCT04365114 | University of Warwick | — |
| Completed | Ruxolitinib for Premalignant Breast Disease NCT02928978 | Julie Nangia | Phase 2 |
| Completed | The Use of Deep Inspiration Breath Hold and Prone Irradiation to Decrease Cardiac Radiation Exposure NCT03375892 | Medical College of Wisconsin | N/A |
| Active Not Recruiting | Intraoperative Radiation Therapy (IORT) in DCIS NCT03216421 | Columbia University | N/A |
| Active Not Recruiting | Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS NCT02926911 | Alliance Foundation Trials, LLC. | N/A |
| Completed | Comparative Effectiveness of Sentinel Lymph Node Biopsy for Ductal Carcinoma In Situ NCT02908178 | Yale University | — |
| Withdrawn | Study to Assess Breast Sensation Before and After Breast Cancer Treatment NCT02817607 | Duke University | N/A |
| Active Not Recruiting | Hong Kong Breast Cancer Study NCT02889458 | The University of Hong Kong | — |
| Unknown | The Mammography and Ultrasonography STudy for Breast Cancer Screening Effectiveness NCT02909426 | Soonchunhyang University Hospital | — |
| Completed | Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy NCT03430765 | Katherine Hadlandsmyth | N/A |
| Terminated | Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer NCT02127073 | Montefiore Medical Center | Phase 2 |
| Completed | Effects of Diet and Exercise on Ductal Carcinoma in Situ NCT02224807 | University of Alabama at Birmingham | N/A |
| Terminated | Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer NCT02137252 | Dana-Farber Cancer Institute | Phase 2 |
| Completed | The Prone Breast Radiation Therapy Trial NCT01815476 | Toronto Sunnybrook Regional Cancer Centre | N/A |
| Completed | A Pilot Pre-operative Window Trial of Black Cohosh in Women With Ductal Carcinoma in Situ NCT01628536 | Yale University | N/A |
| Active Not Recruiting | Safety and Efficacy Study of the Xoft® Axxent® eBx® IORT System® NCT01644669 | Xoft, Inc. | N/A |
| Terminated | Diagnostic Study of Early Breast Cancer Using Ultrasound NCT01391039 | Sunnybrook Health Sciences Centre | N/A |
| Completed | The Breast Duct: Pilot Study of Genomic Sequencing of Exfoliated Ductal Cells Obtained Through Endoscopy and L NCT02121873 | Atossa Therapeutics, Inc. | — |
| Terminated | Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor NCT01372618 | NYU Langone Health | Phase 1 / Phase 2 |
| Completed | Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms NCT01194440 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Terminated | Preoperative Testing of the Anti-Progesterone Mifepristone in Early Stage Breast Cancer NCT01138553 | University of California, San Diego | EARLY_Phase 1 |
| Terminated | A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ NCT01060345 | University of Chicago | Phase 2 |
| Completed | Effect of Pharmacogenomics Differences in Phase I and II Metabolism of Tamoxifen on Efficacy and Toxicity NCT00886535 | Milton S. Hershey Medical Center | — |
| Completed | Selective Omission of Sentinel Lymph Node Biopsy in Mastectomy for Ductal Carcinoma in Situ: Identifying Eligi NCT05961280 | Gangnam Severance Hospital | — |
| Completed | Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial) NCT01023477 | Inova Health Care Services | Phase 1 / Phase 2 |
| Completed | Phase IV Trial to Evaluate Breast Brachytherapy Using the Mammosite-Ml® NCT01448447 | Mercy Research | N/A |
| Terminated | Lapatinib for Treatment of Ductal Carcinoma In Situ (DCIS) of the Breast NCT00857714 | Indiana University | N/A |
| Completed | Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Stagi NCT01060085 | Dartmouth-Hitchcock Medical Center | — |
| Completed | Intraoperative Gamma Camera for Breast Cancer Surgery NCT00757302 | University Hospital, Strasbourg, France | Phase 3 |
| Completed | Electronic Xoft Intersociety Brachytherapy Trial: Electronic Brachytherapy (EBT) For Treatment of Early Stage NCT00742222 | Xoft, Inc. | Phase 4 |
| Unknown | Study Of Intraductal Carboplatin In Women With Ductal Carcinoma In Situ (DCIS) NCT00669747 | Windy Hill Medical, Inc. | Phase 2 |
| Completed | Breast MRI as a Preoperative Tool for DCIS NCT00605982 | Memorial Sloan Kettering Cancer Center | N/A |
| Completed | Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast NCT00496808 | M.D. Anderson Cancer Center | N/A |