| Completed | Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUME NCT04709016 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Tech-Enabled CM for AUD at Scale NCT04581499 | DynamiCare Health | N/A |
| Completed | Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification NCT04003948 | International Center for Ethnobotanical Education, Research, and Service | Phase 2 |
| Recruiting | Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use Disorder NCT04141202 | St. Olavs Hospital | — |
| Withdrawn | Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical Verification NCT05440721 | Click Therapeutics, Inc. | N/A |
| Completed | Innovative Digital Therapeutic for Smoking Cessation NCT03694327 | My Digital Study | N/A |
| Completed | CBT4CBT for Women in Residential Treatment for Substance Use Disorders NCT03678051 | Virginia Commonwealth University | N/A |
| Active Not Recruiting | CB1R in Synthetic Psychoactive Cannabinoids NCT03539575 | Yale University | N/A |
| Unknown | Transcranial Magnetic Stimulation for Cocaine Addiction NCT03333460 | ITAB - Institute for Advanced Biomedical Technologies | N/A |
| Completed | Clinical Trial of Smoking Cessation Mobile Phone Program NCT02656745 | Click Therapeutics, Inc. | N/A |
| Completed | Improving Treatment Outcomes for Prescription Opioid Dependence NCT02543944 | University of Arkansas | Phase 2 / Phase 3 |
| Completed | Automated Recovery Line for Medication Assisted Treatment NCT02124980 | Yale University | N/A |
| Completed | Targeting Effective Analgesia in Clinics for HIV - Intervention NCT02564341 | Boston Medical Center | N/A |
| Completed | Targeting Effective Analgesia in Clinics for HIV - Patient Cohort NCT02525731 | Boston Medical Center | — |
| Completed | Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks NCT02224508 | Kaiser Permanente | — |
| Completed | Impact of Prevention Awareness Group (PAG) on Treatment Attendance and Drug Abstinence Among Substance User NCT02173041 | Macmillan Research Group UK | N/A |
| Completed | How to Ease the Withdrawal of Tranquilizers Among Older Consumers? NCT02281175 | Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal | N/A |
| Completed | Enhancing the Role of Commune Health Workers in HIV and Drug Control: A Randomized Controlled Trial NCT02130921 | University of California, Los Angeles | N/A |
| Completed | HIV, Buprenorphine, and the Criminal Justice System (STRIDE2) NCT03583138 | Yale University | — |
| Completed | Extended Release Naltrexone for Opioid-Dependent Youth NCT01843023 | Friends Research Institute, Inc. | Phase 4 |
| Completed | HIV, Buprenorphine, and the Criminal Justice System NCT01550341 | Yale University | N/A |
| Completed | Development and Testing of Adolescent Twelve-Step Facilitation NCT01449981 | Massachusetts General Hospital | N/A |
| Withdrawn | Testing a Primary Care Model for the Treatment of Opioid Dependence Using Long-acting Injectable Naltrexone (V NCT00675532 | Yale University | N/A |
| Completed | Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders NCT01338506 | Medical University of South Carolina | N/A |
| Completed | Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populat NCT01246401 | Yale University | Phase 1 / Phase 2 |
| Completed | Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits NCT01171677 | NYU Langone Health | N/A |
| Completed | Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans NCT00706901 | VA Office of Research and Development | N/A |
| Completed | Intensive Outpatient Versus Outpatient Treatment With Buprenorphine Among African Americans NCT01096550 | Friends Research Institute, Inc. | N/A |
| Completed | Drug Discrimination in Methadone-Maintained Humans Study 3 NCT01068847 | University of Arkansas | Phase 1 |
| Completed | Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia NCT02396979 | Yale University | Phase 4 |
| Completed | Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use NCT00876941 | Boston Medical Center | Phase 3 |
| Completed | The Effect of Fetal Gender on Maternal Substance Abuse Treatment NCT00882648 | Johns Hopkins University | — |
| Terminated | Oxytocin and Cognitive Behavioral Therapy in Drug Dependence NCT00975416 | National Institute on Drug Abuse (NIDA) | Phase 4 |
| Completed | A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subj NCT00605033 | Indivior Inc. | Phase 4 |
| Completed | A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED) NCT00604188 | Merck Sharp & Dohme LLC | Phase 4 |
| Completed | Pharmacological, Clinical and Statistical Assessment of a New Tool Available for Pharmacodependence Report Eva NCT01052675 | Nantes University Hospital | — |
| Completed | LINK: Aftercare Monitoring Project NCT00265512 | VA Office of Research and Development | N/A |
| Completed | Drug Discrimination in Methadone-Maintained Humans Study 1 NCT00593463 | University of Arkansas | Phase 1 |
| Completed | Addiction Health Evaluation And Disease Management (AHEAD) Study NCT00278447 | Boston Medical Center | Phase 3 |
| Completed | Prometa Pharmacotherapy for Methamphetamine Dependence NCT00260481 | University of California, Los Angeles | Phase 2 / Phase 3 |
| Completed | Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) NCT00798538 | Yale University | Phase 4 |
| Completed | Making Alcoholics Anonymous Easier NCT01382316 | Alcohol Research Group | Phase 3 |
| Completed | Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment) NCT00183118 | Boston Medical Center | Phase 1 / Phase 2 |
| Completed | Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MI NCT00579267 | University of South Florida | — |
| Completed | Automatic Versus Evaluative Components of Cue Reactivity NCT01036126 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Treatment of Polydrug-Using Opiate Dependents During Withdrawal NCT00367874 | Sorlandet Hospital HF | Phase 4 |
| Completed | Brain Function in Response to Motivational Stimuli NCT00047866 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Behavioral Economics of Human Drug Self-Administration NCT00005765 | National Center for Research Resources (NCRR) | — |