| Recruiting | Impact of Capillaroscopy in the Investigation of Diffuse Interstitial Pneumonias NCT07283081 | University Hospital, Bordeaux | N/A |
| Not Yet Recruiting | Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases NCT07329556 | Bursa City Hospital | — |
| Recruiting | The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services NCT06455384 | Unity Health Toronto | N/A |
| Not Yet Recruiting | Study for Patients With Connective Tissue Diseases Who Suffer From Pleuropulmonary Symptoms Clinically and Rad NCT07117552 | Sohag University | — |
| Recruiting | Clinical Study on the Safety and Efficacy of CD19-BCMA CAR-T Cell Therapy for Connective Tissue Diseases NCT07152223 | Guangzhou Bio-gene Technology Co., Ltd | N/A |
| Recruiting | Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic Diseases NCT06732674 | Oslo University Hospital | N/A |
| Recruiting | A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease NCT06716606 | GlaxoSmithKline | Phase 3 |
| Recruiting | ADSCs Therapy in Patients With CTD-ILD NCT06574581 | China Medical University Hospital | Phase 1 / Phase 2 |
| Recruiting | 129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH) NCT06104228 | Bastiaan Driehuys | Phase 2 |
| Recruiting | Telitacicept for the Treatment of Connective Tissue Disease-associated Thrombocytopenia NCT05998759 | Beijing Hospital | Phase 2 |
| Not Yet Recruiting | Connective Tissue Disease Patients With Pulmonary Hypertension NCT05980728 | The First Affiliated Hospital with Nanjing Medical University | — |
| Recruiting | Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture NCT05440240 | Regionshospitalet Silkeborg | Phase 4 |
| Recruiting | REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE) NCT05665556 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | — |
| Terminated | A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis NCT05516758 | Eli Lilly and Company | Phase 2 |
| Unknown | Efficacy and Safety of Pirfenidone in CTD-ILD NCT05505409 | Qilu Hospital of Shandong University | Phase 4 |
| Recruiting | Precision Diagnosis and Care for Families With Pulmonary Fibrosis in Ireland NCT06702228 | Royal College of Surgeons, Ireland | — |
| Recruiting | Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies NCT04993885 | Institute of Hematology & Blood Diseases Hospital, China | Phase 2 |
| Unknown | TPO-RAs Combined With Anti-CD20 Antibody in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies NCT04915482 | Institute of Hematology & Blood Diseases Hospital, China | Phase 2 / Phase 3 |
| Completed | Gene First Approach to Connective Tissue Disease NCT04664478 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Unknown | ERN ReCONNET Study on COVID-19 Vaccination in Rare and Complex Connective Tissue Disease (VACCINATE) NCT04702295 | University of Pisa | — |
| Unknown | Laryngeal Manifestations of Connective Tissue Diseases NCT04582292 | Assiut University | — |
| Unknown | Connective Tissue Diseases and Vitamin D Deficiency NCT05065814 | Gazi University | N/A |
| Unknown | Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD NCT04197050 | RenJi Hospital | Phase 4 |
| Unknown | Telemonitoring of Treatment Effects in Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD NCT04428957 | Medical University of Lodz | N/A |
| Recruiting | Connective Tissue Diseases and Lung Manifestations NCT04095351 | Medical University Innsbruck | — |
| Completed | Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective T NCT03929120 | Mayo Clinic | Phase 1 |
| Enrolling By Invitation | A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Exten NCT03683186 | United Therapeutics | Phase 3 |
| Unknown | Immunosuppressant Combined With Pirfenidone in CTD-ILD NCT04928586 | Qilu Hospital of Shandong University | Phase 4 |
| Completed | The Effect of Connective Tissue Massage in Patients With Migraine NCT04171362 | Ankara Yildirim Beyazıt University | N/A |
| Unknown | Prognostic Value of Anti-Ro52 Antibodies in Connective Tissue Diseases (a-Ro52) NCT03565601 | Central Hospital, Nancy, France | — |
| Recruiting | The Clinical Features and Pregnancy Outcomes of CTD Patients NCT04918524 | Qilu Hospital of Shandong University | — |
| Completed | A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients NCT03626688 | United Therapeutics | Phase 3 |
| Enrolling By Invitation | University of Virginia Natural History Study NCT04896138 | University of Virginia | — |
| Completed | Effect of Synbiotic on Immune Response, Gut Permeability and Microbiota in Patient With Connective Tissue Dise NCT03494036 | Fakultas Kedokteran Universitas Indonesia | N/A |
| Unknown | Study of Sirolimus in CTD-TP in China NCT03688191 | Peking Union Medical College Hospital | Phase 4 |
| Unknown | Pulmonary Hypertension Screening for Rheumatology Patients (SOPHIE) NCT03446339 | The University of Hong Kong | — |
| Active Not Recruiting | Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypert NCT02682511 | Cumberland Pharmaceuticals | Phase 2 |
| Completed | Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid Arthritis NCT03337165 | Russian Academy of Medical Sciences | Phase 1 |
| Unknown | Prevalence of Pulmonary Arterial Hypertension in Patients With Connective Tissue Diseases in Egyptian Patients NCT02768259 | Cairo University | — |
| Unknown | Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Dis NCT03214263 | Rigshospitalet, Denmark | — |
| Completed | A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy NCT02392130 | LEO Pharma | Phase 1 |
| Completed | Early Detection of Cardiac Impairment and Prediction of RV Hypertrophy in Patients With CTD NCT04297371 | RenJi Hospital | — |
| Completed | Efficacy and Safety of Eltrombopag for Refractory Thrombocytopenia Associated With Connective Tissue Disease NCT06458803 | Tongji Hospital | — |
| Completed | An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis NCT01656278 | Professor of Rheumatology, MD, DMSci, Kim Horslev-Petersen | N/A |
| Unknown | Novel Form of Acquired Long QT Syndrome NCT04169100 | Narrows Institute for Biomedical Research | Phase 4 |
| Terminated | Collection of Tissue Specimens for Analysis and Establishment of Cell Cultures NCT00802607 | National Institute of Dental and Craniofacial Research (NIDCR) | — |
| Completed | CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study NCT00522002 | George Washington University | — |
| Completed | Oral Type I Collagen for Relieving Scleroderma NCT00005675 | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Phase 2 |
| Completed | Absorption of Corticosteroids in Children With Juvenile Dermatomyositis NCT00004357 | Northwestern University | Phase 2 |
| Completed | Study of Silicone-Associated Connective Tissue Diseases NCT00001330 | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | — |