| Not Yet Recruiting | Jianpi Lishi Jiedu Granules for Prevention of Postoperative Recurrence in Colorectal Advanced Adenomas NCT07505056 | Nanjing First Hospital, Nanjing Medical University | Phase 3 |
| Not Yet Recruiting | BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention NCT07162337 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | Colorectal Omics and ofCS Proteoglycans (COCO) in Screening and a Diagnostic Pathway NCT07237984 | Nordsjaellands Hospital | — |
| Suspended | Protocol to Validate the Performance of the LifeKit® Prevent Colorectal Neoplasia Test for CRC Screening NCT04693546 | Metabiomics Corp | — |
| Recruiting | Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors NCT07095517 | Massachusetts General Hospital | Phase 1 |
| Not Yet Recruiting | Epigenetic Factors of Colorectal Adenoma in Korean NCT07366554 | Bundang CHA Hospital | — |
| Not Yet Recruiting | Quantitative Fecal Immunochemical Test for Detection of Colorectal Cancer and Precancerous Lesions in Sohag NCT07410546 | Sohag University | — |
| Not Yet Recruiting | Recurrence After Gastric and Intestinal Polyp Resection NCT07314554 | LanZhou University | — |
| Not Yet Recruiting | Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced A NCT05636085 | Mainz Biomed | — |
| Not Yet Recruiting | Evaluating the Clinical Value of Transparent Cap-Assisted Second Examination of the Sigmoid Colon for Improvin NCT07261319 | Fudan University | N/A |
| Not Yet Recruiting | Cold Snare Versus Cold Forceps Polypectomy for Small Lesions NCT06970808 | Azienda USL Modena | N/A |
| Not Yet Recruiting | The Effect of Oral Clostridium Butyricum on the Recurrence After Colonoscopic Resection of Colorectal Adenoma NCT07167342 | The Affiliated Hospital of Qingdao University | Phase 4 |
| Not Yet Recruiting | Development and Validation of an Artificial Intelligence-assisted System for Bowel Cleanliness Assessment Base NCT07150130 | Fudan University | — |
| Recruiting | Enhanced White Light Endoscopy Versus Conventional White Light Endoscopy for Colorectal Adenoma Detection: A R NCT06979232 | Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | Risk of Metachronous Advanced Colorectal Neoplastic Among Individuals With Varying Numbers of Non-Advanced Ade NCT07302139 | Fudan University | — |
| Not Yet Recruiting | Shenbai Granules for Preventing Malignant Transformation of High-risk Colorectal Adenomas NCT07129499 | Jiangsu Famous Medical Technology Co., Ltd. | N/A |
| Not Yet Recruiting | Shenbai Granules for Preventing Recurrence of Low-Risk Colorectal Adenomas NCT07123116 | Jiangsu Famous Medical Technology Co., Ltd. | N/A |
| Not Yet Recruiting | Transparent Cap-Assisted Colonoscopy Combined With Computer-Aided Detection in Improving the Detection Rate of NCT07097350 | Fudan University | N/A |
| Recruiting | New bioMarkers tO straTIfy cOlorectal caNcer Referrals NCT07035691 | Queen Mary University of London | — |
| Not Yet Recruiting | Advanced Adenoma Detection With 3D Imaging Device During Colonoscopy NCT06924489 | Xijing Hospital of Digestive Diseases | N/A |
| Recruiting | PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System NCT06133387 | EndoQuest Robotics, Inc. | N/A |
| Recruiting | Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, NCT06307938 | Helse Nord-Trøndelag HF | — |
| Recruiting | Evaluation of a CAM System for Colorectal Polyp Size Measurement NCT06715384 | Changhai Hospital | N/A |
| Not Yet Recruiting | Phase II Clinical Study of AC591 in Preventing Oxaliplatin-Induced Peripheral Neuropathy NCT06722950 | Shandong New Time Pharmaceutical Co., LTD | Phase 2 |
| Not Yet Recruiting | Clinical Outcomes After EMR or ESD of Colorectal Neoplasms - A Multicenter Registry NCT05653960 | Chinese University of Hong Kong | — |
| Recruiting | Evaluation of Gixam's Performance in a FIT Negative Population NCT06612281 | Jubaan Ltd. | Phase 2 |
| Completed | Spectral Focused Imaging Versus White Light Imaging in Colorectal Adenoma Detection NCT06603948 | Shanghai Jiao Tong University School of Medicine | N/A |
| Recruiting | 6-year Follow-up Data After the Berberine Intervention Trial NCT06629051 | Shanghai Jiao Tong University School of Medicine | — |
| Active Not Recruiting | Evaluation of 'WAYMED Endo CL CS' for Automated Detection and Diagnosis of Colorectal Adenoma and Non-Adenoma NCT07470827 | WAYCEN Inc | — |
| Not Yet Recruiting | Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy NCT06067620 | Jeremy Meyer | N/A |
| Recruiting | Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Reducing Recurrence of Colorectal Adenoma (CR NCT06205862 | Shenzhen Hospital of Southern Medical University | Phase 2 |
| Completed | Artificial-intelligence-based QUAntification of Size measuremeNts of Adenoma in Routine Endoscopy NCT06040710 | Wuerzburg University Hospital | — |
| Recruiting | Epigenetic Regulation of Colorectal Polyps and Cancer NCT06206603 | Region Skane | — |
| Not Yet Recruiting | Integrated Chinese and Western Medicine Specialized Disease Cohort for Colorectal Cancer NCT06136026 | Jiangsu Famous Medical Technology Co., Ltd. | — |
| Recruiting | Application Evaluation Research on the Artificial Intelligence-assisted Support System for the Diagnosis of Co NCT07073430 | Renmin Hospital of Wuhan University | — |
| Recruiting | Performance and Safety of MiWEndo-assisted Colonoscopy (MiWEndo II) NCT05988645 | MiWEndo Solutions S.L. | N/A |
| Recruiting | Colonoscopy vs Stool Testing for Older Adults With Colon Polyps NCT05612347 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | IMPACT OF SEDENTARY BEHAVIOR IN THE HOMEOSTASIS OF THE DIGESTIVE ECOSYSTEM NCT07398820 | Clínica Universidad de los Andes | — |
| Unknown | the Serum Metabolite Based PrecogColo Dx Test for Advanced Colorectal Neoplasia Screening NCT05870696 | Peking University Third Hospital | — |
| Recruiting | Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Col NCT06957626 | Peking Union Medical College Hospital | — |
| Enrolling By Invitation | Validation of the Global Polypectomy Assessment Tool (GPAT) NCT05877456 | University Hospital, Ghent | — |
| Withdrawn | Impact of Hybrid-ESD+ and LiftUp® on the en Bloc/R0 Rate in Colorectal Adenomas Between 2 and 3 cm NCT05517369 | Wuerzburg University Hospital | N/A |
| Recruiting | A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacter NCT05592886 | Chinese University of Hong Kong | N/A |
| Completed | Technical Failure During Colorectal Endoscopic Full Thickness Resection (EFTR): The "Through Thick and Thin" S NCT05913453 | Azienda Unità Sanitaria Locale della Romagna | — |
| Completed | A Study on a Blood-based Dual-target Test for CRC Detection NCT05508503 | Changhai Hospital | — |
| Completed | Feasibility and Safety of MiWEndo-assisted Colonoscopy NCT05477836 | MiWEndo Solutions S.L. | N/A |
| Completed | Application of Hyperspectral Imaging Analysis Technology in the Diagnosis of Colorectal Cancer Based on Colono NCT05576506 | Shandong University | — |
| Completed | Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy NCT05740137 | Ismail Gögenur | N/A |
| Unknown | Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy NCT05754229 | Ismail Gögenur | N/A |
| Withdrawn | Predicting Risk for Post-polypectomy Colorectal Cancer NCT05606081 | Kaiser Permanente | N/A |
| Recruiting | Serial Gut Microbiome and Bacterial Gene Markers Changes After Endoscopic Resection of Colorectal Advanced Neo NCT05381792 | Chinese University of Hong Kong | — |
| Withdrawn | Molecular Effects of Aspirin & Metformin on Colonic Epithelium NCT05158374 | University of Edinburgh | N/A |
| Unknown | Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Trac NCT05247346 | University Medical Center Groningen | N/A |
| Unknown | The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) Study NCT05402124 | University of Calgary | Phase 2 |
| Recruiting | Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia NCT05405673 | Chinese University of Hong Kong | — |
| Completed | Evaluation of CAD-EYE/SCALE-EYE for Detection, Classification, and Measurement of Colorectal Polyps: a Prospec NCT05236790 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Optimal Selenium for Bowel Polyps (OSCAR) NCT04952129 | University of Auckland, New Zealand | Phase 1 |
| Unknown | Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence NCT05587452 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | — |
| Unknown | Fecal Immunochemical Test for Advanced Adenoma Detection in Colorectal Cancer Screening NCT05200611 | Shandong University | — |
| Recruiting | Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA) NCT05144152 | Chinese University of Hong Kong | — |
| Unknown | Research on Endoscopic Precision Biopsy. NCT05261932 | Beijing Tsinghua Chang Gung Hospital | — |
| Completed | Evaluation of a New Blood-based Test to Detect Colorectal Cancer and Its Precursors NCT04980443 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | Establishment and Validation of a Predictive Model for the Risk of Colorectal Advanced Adenomas NCT05152082 | The First Affiliated Hospital with Nanjing Medical University | — |
| Unknown | Fecal DNA Methylation Test for Colorectal Cancer Screening NCT04823793 | Tri-Service General Hospital | — |
| Completed | COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy? NCT04723758 | South Tyneside and Sunderland NHS Foundation Trust | N/A |
| Completed | Investigating the Gut Microbiota of Individuals With Adenoma, Advanced Adenoma and Colorectal Cancer NCT07321548 | Chinese University of Hong Kong | — |
| Completed | Clinical Trial Evaluating External Evaluation and Training on the Incomplete Resection (POLIPEVA Study) NCT04636619 | Hospital del Rio Hortega | N/A |
| Completed | 9 Minutes for Tandem Colonoscopy Withdrawal NCT04797065 | Changhai Hospital | N/A |
| Completed | PRevention Using EPA Against coloREctal Cancer NCT04216251 | Massachusetts General Hospital | Phase 1 / Phase 2 |
| Completed | Reducing Colonoscopies in Patients Without Significant Bowel Disease NCT04516785 | University Hospitals Coventry and Warwickshire NHS Trust | — |
| Completed | A Prospective Investigation of the ColubrisMX ELS System NCT04192565 | ColubrisMX | N/A |
| Completed | A New Quantitative Fecal Immunochemical Test in Detecting Colorectal Advanced Adenoma NCT04473677 | Shandong University | — |
| Unknown | Metformin for the Prevention of CRA Recurrence NCT04885426 | Jing-yuan Fang, MD, Ph. D | N/A |
| Unknown | Efficacy and Safety of Cold Snare Polypectomy (CSP) of Intermediate Sized Colorectal Polyps 10-15 mm NCT04464837 | Technical University of Munich | N/A |
| Unknown | To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard NCT04196088 | Docbot, Inc. | N/A |
| Unknown | Development and Validation of an Artificial Intelligence-assisted Strategy Selection System for Colonoscopy Cl NCT04444908 | Renmin Hospital of Wuhan University | — |
| Completed | FIT and Fecal Calprotectin in Patients With Chronic Lower GI Symptoms NCT05514561 | Mahidol University | — |
| Completed | Panoramic Screening by Complete Colonoscopy in the Management of Colorectal Adenomas NCT03961893 | Institut Paoli-Calmettes | N/A |
| Unknown | Computer-aided Detection During Screening Colonoscopy NCT05734820 | Instituto Ecuatoriano de Enfermedades Digestivas | N/A |
| Recruiting | COLO-COHORT (Colorectal Cancer Cohort) Study NCT04185779 | South Tyneside and Sunderland NHS Foundation Trust | — |
| Completed | Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controll NCT04490551 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Active Not Recruiting | Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer NCT03796884 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | Phase 2 |
| Completed | Comparisons of Endo-Wing-assisted Colonoscopy Versus Standard Colonoscopy in Improving Adenoma Detection Rate NCT06859125 | Universiti Kebangsaan Malaysia Medical Centre | N/A |
| Recruiting | Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile NCT06452745 | Institut Investigacio Sanitaria Pere Virgili | — |
| Completed | a Low-residue Diet for Bowel Preparation NCT03943758 | Changhai Hospital | N/A |
| Completed | Ginger and Gut Microbiome (GINGER) NCT03268655 | University of Minnesota | N/A |
| Completed | Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy NCT03560128 | Indiana University | N/A |
| Unknown | Adenoma Detection Rate With Endocuff-Assisted Colonoscopy - an Italian Trial NCT03612674 | Cancer Prevention and Research Institute, Italy | N/A |
| Completed | Three Arm Rand Trial of HD Light vs Reveal® Cap vs Endocuff Cap for Detection of Colorectal Adenomas (TRACE) NCT03952611 | Midwest Biomedical Research Foundation | N/A |
| Completed | Use of iFOBT in Patients Presenting With Alarm Symptoms of Colorectal Cancer NCT03367611 | University of Aarhus | N/A |
| Completed | EndoRings Colonoscopy vs Standard Colonoscopy NCT03418662 | Indiana University | N/A |
| Active Not Recruiting | Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma NCT02965703 | National Cancer Institute (NCI) | Phase 2 |
| Completed | ObeSity Related Colorectal Adenoma Risk NCT03663062 | South Tyneside and Sunderland NHS Foundation Trust | — |
| Completed | Standard Colonoscopy Versus Colonoscopy With Endocuff Vision NCT03361917 | Indiana University | N/A |
| Unknown | Examining Techniques on Adenoma Miss Rate in Proximal Colon NCT03355443 | Changhai Hospital | N/A |
| Unknown | Volatiles in Breath and Headspace Analysis - Diagnostic Markers NCT03228095 | University of Latvia | — |
| Terminated | Adenoma Detection Rate in Colonoscopy Performed With EndoRings NCT03219918 | Zealand University Hospital | N/A |
| Terminated | Lifestyle Change for Better Health NCT03286699 | University of Pittsburgh | N/A |
| Unknown | Novel Blood-based Colorectal Cancer Screening Method Using Natural Killer Cell Activity and Gene Panel Express NCT03289988 | Yonsei University | — |
| Unknown | Comparison of Detection and Miss Rates of Blue Laser Imaging Versus Conventional White Light Colonoscopy NCT02982447 | Yangzhou No.1 People's Hospital | N/A |
| Unknown | Evaluation of the Resection of Adenoma and Colic Adenocarcinoma by EMR Piecemeal or EMR/ESD Hybrid Technique NCT02935049 | Institut Paoli-Calmettes | — |
| Completed | Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial NCT03234725 | Bács-Kiskun County Teaching Hospital | — |
| Completed | To Investigate Risk of Colorectal Neoplasms in First-degree Relatives of Patients With Non-advanced Adenomas NCT02521727 | Chinese University of Hong Kong | — |
| Completed | Evaluation of the Colonoscope With Vision to 330 ° (Full Spectrum Endoscopy) in the Detection of Colorectal Ad NCT02859870 | Institut Paoli-Calmettes | — |
| Unknown | Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Pol NCT05638542 | Seoul National University Bundang Hospital | — |
| Unknown | Intubation Techniques on Colonoscopy Quality (SINOCOLO2013) NCT01919463 | Changhai Hospital | N/A |
| Completed | Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence NCT02226185 | Shanghai Jiao Tong University School of Medicine | Phase 2 / Phase 3 |
| Active Not Recruiting | Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps NCT02134925 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Evaluation of Flexible Sigmoidoscopy Screening as an Adjunct to the National FOBT Screening Programme in Scotl NCT02560194 | University of Dundee | N/A |
| Completed | Anthocyanin Extract and Phospholipid Curcumin in Colorectal Adenoma NCT01948661 | Ente Ospedaliero Ospedali Galliera | N/A |
| Unknown | Study of Calcium Plus Vitamin D Supplementation in Prevention of Colorectal Adenomas Recurrence NCT02143505 | Shanghai Jiao Tong University School of Medicine | Phase 2 / Phase 3 |
| Completed | Volatile Markers in Digestive Cancer NCT02332213 | University of Latvia | — |
| Unknown | Endocuff Adenoma Detection Rate Pilot Study NCT01761097 | Cambridge University Hospitals NHS Foundation Trust | N/A |
| Unknown | Efficacy Combined Fecal Immunochemical Test-Sigmoidoscopy for the Detection of Advanced Colorectal Neoplasia NCT01767870 | Yonsei University | Phase 4 |
| Completed | Molecular Imaging of Epidermal Growth Factor Receptor in Colorectal Neoplasia Using Confocal Laser Endomicrosc NCT01372189 | Shandong University | — |
| Unknown | Familial Colorectal Cancer Registry in Hispanics NCT00927680 | University of Puerto Rico | — |
| Completed | Effect of Vitamin D and Calcium on Genes in the Colon NCT00298545 | Rockefeller University | Phase 1 |
| Completed | Evaluation of Surgically Resected Colorectal Adenomas and Carcinomas After 7 Days Pretreatment With Celecoxib NCT00582660 | University of Alabama at Birmingham | Phase 2 |
| Completed | Prevention of Colorectal Sporadic Adenomatous Polyps (PRESAP) NCT00141193 | Pfizer | Phase 3 |
| Completed | Colorectal Neoplasia Screening w Colonoscopy in Asymptomatic Women at Regional Navy/Army Medical Ctrs: The CON NCT00339950 | National Cancer Institute (NCI) | — |
| Completed | A Study to Evaluate the Effect of MK0966 (Rofecoxib) on the Recurrence of Colorectal Adenomas (0966-122) NCT00282386 | Merck Sharp & Dohme LLC | Phase 3 |
| Unknown | Detection of Colorectal Adenomas in Côte-d'Or NCT02859714 | Centre Hospitalier Universitaire Dijon | — |