Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT05606081

Predicting Risk for Post-polypectomy Colorectal Cancer

Status
Withdrawn
Phase
N/A
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Kaiser Permanente · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Accepted

Summary

This originated as an observational study of Kaiser Permanente Northern California (KPNC) patients with a history of adenoma diagnosed by colonoscopy who received a subsequent surveillance colonoscopy between 2014 and 2019. The original goal of the study was to develop a risk prediction model that would help identify patients at highest risk for a diagnosis of advanced neoplasia (colorectal cancer and/or advanced adenoma) at or within 6 months following their surveillance colonoscopy. Candidate predictors of interest included patient demographics, medical history, and details related to the index colonoscopy. The investigators are now at the implementation stage and applying the risk prediction model to patients awaiting surveillance colonoscopy at select KPNC service areas to help identify those at highest risk for colorectal cancer based on their risk scores.

Detailed description

In the implementation stage, the risk prediction model is being applied to patients who are awaiting surveillance colonoscopy at select KPNC service areas to help identify those at highest risk for colorectal cancer based on their risk scores. The prediction model is being used in 2-3 service area to identify about 60-80 patients per month who are at highest risk for colorectal cancer based on their risk scores. Risk scores represent one of a number of factors being considered for prioritizing patients for colonoscopy.

Conditions

Interventions

TypeNameDescription
DEVICELogistic regression risk modelLogistic regression model to assign risk score, plus time overdue and PROMPT risk category

Timeline

Start date
2022-09-01
Primary completion
2023-09-01
Completion
2023-12-31
First posted
2022-11-04
Last updated
2023-02-28

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05606081. Inclusion in this directory is not an endorsement.